Northwestern University Feinberg School of Medicine

Kathleen Green Lab

Publications

Learn more about the work that we do in the Green laboratory through our recent publications.

  1. Hegazy M, Cohen-Barak E, Koetsier JL, Najor NA, Arvanitis C, Sprecher E, Green KJ, Godsel LM  Proximity Ligation Assay for Detecting Protein-Protein Interactions and Protein Modifications in Cells and Tissues in Situ.  Curr Protoc Cell Biol  2020 Dec;89(1):e115. doi:10.1002/cpcb.115
  2. Green KJ, Roth-Carter Q, Niessen CM, Nichols SA  Tracing the Evolutionary Origin of Desmosomes.  Curr Biol  2020 May 18;30(10):R535-R543. pii:S0960-9822(20)30417-6
  3. Broussard JA, Jaiganesh A, Zarkoob H, Conway DE, Dunn AR, Espinosa HD, Janmey PA, Green KJ  Scaling up single-cell mechanics to multicellular tissues - the role of the intermediate filament-desmosome network.  J Cell Sci  2020 03 16;133(6). pii:jcs228031
  4. Green KJ, Jaiganesh A, Broussard JA  Desmosomes:  Essential contributors to an integrated intercellular junction network.  F1000Res  2019;8. pii:F1000 Faculty Rev-2150
  5. Arnette CR, Roth-Carter QR, Koetsier JL, Broussard JA, Burks HE, Cheng K, Amadi C, Gerami P, Johnson JL, Green KJ  Keratinocyte cadherin desmoglein 1 controls melanocyte behavior through paracrine signaling.  Pigment Cell Melanoma Res  2020 03;33(2):305-317. doi:10.1111/pcmr.12826
  6. Cohen-Barak E, Godsel LM, Koetsier JL, Hegazy M, Kushnir-Grinbaum D, Hammad H, Danial-Farran N, Harmon R, Khayat M, Bochner R, Peled A, Rozenblat M, Krausz J, Sarig O, Johnson JL, Ziv M, Shalev SA, Sprecher E, Green KJ  The Role of Desmoglein 1 in Gap Junction Turnover Revealed through the Study of SAM Syndrome.  J Invest Dermatol  2020 03;140(3):556-567.e9. pii:S0022-202X(19)33151-3
  7. Elliott PM, Anastasakis A, Asimaki A, Basso C, Bauce B, Brooke MA, Calkins H, Corrado D, Duru F, Green KJ, Judge DP, Kelsell D, Lambiase PD, McKenna WJ, Pilichou K, Protonotarios A, Saffitz JE, Syrris P, Tandri H, Te Riele A, Thiene G, Tsatsopoulou A, van Tintelen JP  Definition and treatment of arrhythmogenic cardiomyopathy: an updated expert panel report.  Eur J Heart Fail  2019 08;21(8):955-964. doi:10.1002/ejhf.1534
  8. Valenzuela-Iglesias A, Burks HE, Arnette CR, Yalamanchili A, Nekrasova O, Godsel LM, Green KJ  Desmoglein 1 Regulates Invadopodia by Suppressing EGFR/Erk Signaling in an Erbin-Dependent Manner.  Mol Cancer Res  2019 05;17(5):1195-1206. doi:10.1158/1541-7786.MCR-18-0048
  9. Maruthappu T, Posafalvi A, Castelletti S, Delaney PJ, Syrris P, O'Toole EA, Green KJ, Elliott PM, Lambiase PD, Tinker A, McKenna WJ, Kelsell DP  Loss-of-function desmoplakin I and II mutations underlie dominant arrhythmogenic cardiomyopathy with a hair and skin phenotype.  Br J Dermatol  2019 05;180(5):1114-1122. doi:10.1111/bjd.17388
  10. Yang R, Broussard JA, Green KJ, Espinosa HD  Techniques to stimulate and interrogate cell-cell adhesion mechanics.  Extreme Mech Lett  2018 Apr;20:125-139. doi:10.1016/j.eml.2017.12.002
  11. Kam CY, Dubash AD, Magistrati E, Polo S, Satchell KJF, Sheikh F, Lampe PD, Green KJ  Desmoplakin maintains gap junctions by inhibiting Ras/MAPK and lysosomal degradation of connexin-43.  J Cell Biol  2018 09 03;217(9):3219-3235. doi:10.1083/jcb.201710161
  12. Mohamad J, Sarig O, Godsel LM, Peled A, Malchin N, Bochner R, Vodo D, Rabinowitz T, Pavlovsky M, Taiber S, Fried M, Eskin-Schwartz M, Assi S, Shomron N, Uitto J, Koetsier JL, Bergman R, Green KJ, Sprecher E  Filaggrin 2 Deficiency Results in Abnormal Cell-Cell Adhesion in the Cornified Cell Layers and Causes Peeling Skin Syndrome Type A.  J Invest Dermatol  2018 08;138(8):1736-1743. pii:S0022-202X(18)31969-9
  13. Polivka L, Hadj-Rabia S, Bal E, Leclerc-Mercier S, Madrange M, Hamel Y, Bonnet D, Mallet S, Lepidi H, Ovaert C, Barbet P, Dupont C, Neven B, Munnich A, Godsel LM, Campeotto F, Weil R, Laplantine E, Marchetto S, Borg JP, Weis WI, Casanova JL, Puel A, Green KJ, Bodemer C, Smahi A  Epithelial barrier dysfunction in desmoglein-1 deficiency.  J Allergy Clin Immunol  2018 08;142(2):702-706.e7. pii:S0091-6749(18)30616-X
  14. Nekrasova O, Harmon RM, Broussard JA, Koetsier JL, Godsel LM, Fitz GN, Gardel ML, Green KJ  Desmosomal cadherin association with Tctex-1 and cortactin-Arp2/3 drives perijunctional actin polymerization to promote keratinocyte delamination.  Nat Commun  2018 03 13;9(1):1053. doi:10.1038/s41467-018-03414-6
  15. Vodo D, O'Toole EA, Malchin N, Lahav A, Adir N, Sarig O, Green KJ, Smith FJD, Sprecher E  Striate palmoplantar keratoderma resulting from a missense mutation in DSG1.  Br J Dermatol  2018 09;179(3):755-757. doi:10.1111/bjd.16320
  16. Broussard JA, Green KJ  Research Techniques Made Simple: Methodology and Applications of Förster Resonance Energy Transfer (FRET) Microscopy.  J Invest Dermatol  2017 11;137(11):e185-e191. pii:S0022-202X(17)32952-4
  17. Quinlan RA, Schwarz N, Windoffer R, Richardson C, Hawkins T, Broussard JA, Green KJ, Leube RE  A rim-and-spoke hypothesis to explain the biomechanical roles for cytoplasmic intermediate filament networks.  J Cell Sci  2017 Oct 15;130(20):3437-3445. doi:10.1242/jcs.202168
  18. Rübsam M, Broussard JA, Wickström SA, Nekrasova O, Green KJ, Niessen CM  Adherens Junctions and Desmosomes Coordinate Mechanics and Signaling to Orchestrate Tissue Morphogenesis and Function: An Evolutionary Perspective.  Cold Spring Harb Perspect Biol  2018 11 01;10(11). pii:a029207
  19. Najor NA, Fitz GN, Koetsier JL, Godsel LM, Albrecht LV, Harmon R, Green KJ  Epidermal Growth Factor Receptor neddylation is regulated by a desmosomal-COP9 (Constitutive Photomorphogenesis 9) signalosome complex.  Elife  2017 09 11;6. doi:10.7554/eLife.22599
  20. Broussard JA, Yang R, Huang C, Nathamgari SSP, Beese AM, Godsel LM, Hegazy MH, Lee S, Zhou F, Sniadecki NJ, Green KJ, Espinosa HD  The desmoplakin-intermediate filament linkage regulates cell mechanics.  Mol Biol Cell  2017 Nov 07;28(23):3156-3164. doi:10.1091/mbc.E16-07-0520
  21. Eskin-Schwartz M, Drozhdina M, Sarig O, Gat A, Jackman T, Isakov O, Shomron N, Samuelov L, Malchin N, Peled A, Vodo D, Hovnanian A, Ruzicka T, Koshkin S, Harmon RM, Koetsier JL, Green KJ, Paller AS, Sprecher E  Epidermolytic Ichthyosis Sine Epidermolysis.  Am J Dermatopathol  2017 Jun;39(6):440-444. doi:10.1097/DAD.0000000000000674
  22. Jones JC, Kam CY, Harmon RM, Woychek AV, Hopkinson SB, Green KJ  Intermediate Filaments and the Plasma Membrane.  Cold Spring Harb Perspect Biol  2017 Jan 03;9(1). pii:a025866
  23. Samuelov L, Li Q, Bochner R, Najor NA, Albrecht L, Malchin N, Goldsmith T, Grafi-Cohen M, Vodo D, Fainberg G, Meilik B, Goldberg I, Warshauer E, Rogers T, Edie S, Ishida-Yamamoto A, Burzenski L, Erez N, Murray SA, Irvine AD, Shultz L, Green KJ, Uitto J, Sprecher E, Sarig O  SVEP1 plays a crucial role in epidermal differentiation.  Exp Dermatol  2017 05;26(5):423-430. doi:10.1111/exd.13256
  24. Green KJ, Niessen CM  Degrees of Freedom: Your Future in Biomedical Research.  J Invest Dermatol  2016 06;136(6):1073-1076. pii:S0022-202X(16)31015-6
  25. Dubash AD, Kam CY, Aguado BA, Patel DM, Delmar M, Shea LD, Green KJ  Plakophilin-2 loss promotes TGF-β1/p38 MAPK-dependent fibrotic gene expression in cardiomyocytes.  J Cell Biol  2016 Feb 15;212(4):425-38. doi:10.1083/jcb.201507018
  26. Arnette C, Koetsier JL, Hoover P, Getsios S, Green KJ  In Vitro Model of the Epidermis: Connecting Protein Function to 3D Structure.  Methods Enzymol  2016;569:287-308. doi:10.1016/bs.mie.2015.07.015
  27. Boyden LM, Kam CY, Hernández-Martín A, Zhou J, Craiglow BG, Sidbury R, Mathes EF, Maguiness SM, Crumrine DA, Williams ML, Hu R, Lifton RP, Elias PM, Green KJ, Choate KA  Dominant de novo DSP mutations cause erythrokeratodermia-cardiomyopathy syndrome.  Hum Mol Genet  2016 Jan 15;25(2):348-57. doi:10.1093/hmg/ddv481
  28. McAleer MA, Pohler E, Smith FJ, Wilson NJ, Cole C, MacGowan S, Koetsier JL, Godsel LM, Harmon RM, Gruber R, Crumrine D, Elias PM, McDermott M, Butler K, Broderick A, Sarig O, Sprecher E, Green KJ, McLean WH, Irvine AD  Severe dermatitis, multiple allergies, and metabolic wasting syndrome caused by a novel mutation in the N-terminal plakin domain of desmoplakin.  J Allergy Clin Immunol  2015 Nov;136(5):1268-76. doi:10.1016/j.jaci.2015.05.002
  29. Sassano A, Mavrommatis E, Arslan AD, Kroczynska B, Beauchamp EM, Khuon S, Chew TL, Green KJ, Munshi HG, Verma AK, Platanias LC  Human Schlafen 5 (SLFN5) Is a Regulator of Motility and Invasiveness of Renal Cell Carcinoma Cells.  Mol Cell Biol  2015 Aug;35(15):2684-98. doi:10.1128/MCB.00019-15
  30. Albrecht LV, Zhang L, Shabanowitz J, Purevjav E, Towbin JA, Hunt DF, Green KJ  GSK3- and PRMT-1-dependent modifications of desmoplakin control desmoplakin-cytoskeleton dynamics.  J Cell Biol  2015 Mar 02;208(5):597-612. doi:10.1083/jcb.201406020
  31. Broussard JA, Getsios S, Green KJ  Desmosome regulation and signaling in disease.  Cell Tissue Res  2015 Jun;360(3):501-12. doi:10.1007/s00441-015-2136-5
  32. Moy I, Todorović V, Dubash AD, Coon JS, Parker JB, Buranapramest M, Huang CC, Zhao H, Green KJ, Bulun SE  Estrogen-dependent sushi domain containing 3 regulates cytoskeleton organization and migration in breast cancer cells.  Oncogene  2015 Jan 15;34(3):323-33. doi:10.1038/onc.2013.553
View all publications by Dr. Kathleen J. Green listed in the National Library of Medicine (PubMed).