Northwestern University Feinberg School of Medicine

Kathleen J. Green Lab

Publications

Learn more about the work that we do in the Green laboratory through our recent publications.

  1. Roth-Carter QR, Koetsier JL, Broussard JA, Green KJ  Organotypic Human Skin Cultures Incorporating Primary Melanocytes.  Curr Protoc  2022 Sep;2(9):e536. doi:10.1002/cpz1.536
  2. Green KJ, Niessen CM, Rübsam M, Perez White BE, Broussard JA  The Desmosome-Keratin Scaffold Integrates ErbB Family and Mechanical Signaling to Polarize Epidermal Structure and Function.  Front Cell Dev Biol  2022;10:903696. doi:10.3389/fcell.2022.903696
  3. Broussard JA, Green KJ  Plectin pulls it together, coupling the cortical actin and intermediate filament cytoskeletons.  J Cell Biol  2022 03 07;221(3). pii:e202201054
  4. Godsel LM, Roth-Carter QR, Koetsier JL, Tsoi LC, Huffine AL, Broussard JA, Fitz GN, Lloyd SM, Kweon J, Burks HE  et al.  Translational implications of Th17-skewed inflammation due to genetic deficiency of a cadherin stress sensor.  J Clin Invest  2022 02 01;132(3). doi:10.1172/JCI144363
  5. Hegazy M, Perl AL, Svoboda SA, Green KJ  Desmosomal Cadherins in Health and Disease.  Annu Rev Pathol  2022 01 24;17:47-72. doi:10.1146/annurev-pathol-042320-092912
  6. Indra I, Troyanovsky RB, Green KJ, Troyanovsky SM  Plakophilin 3 and Par3 facilitate desmosomes' association with the apical junctional complex.  Mol Biol Cell  2021 09 01;32(19):1824-1837. doi:10.1091/mbc.E21-01-0001
  7. Broussard JA, Koetsier JL, Hegazy M, Green KJ  Desmosomes polarize and integrate chemical and mechanical signaling to govern epidermal tissue form and function.  Curr Biol  2021 08 09;31(15):3275-3291.e5. pii:S0960-9822(21)00680-1
  8. Raya-Sandino A, Luissint AC, Kusters DHM, Narayanan V, Flemming S, Garcia-Hernandez V, Godsel LM, Green KJ, Hagen SJ, Conway DE  et al.  Regulation of intestinal epithelial intercellular adhesion and barrier function by desmosomal cadherin desmocollin-2.  Mol Biol Cell  2021 04 15;32(8):753-768. doi:10.1091/mbc.E20-12-0775
  9. Hegazy M, Cohen-Barak E, Koetsier JL, Najor NA, Arvanitis C, Sprecher E, Green KJ, Godsel LM  Proximity Ligation Assay for Detecting Protein-Protein Interactions and Protein Modifications in Cells and Tissues in Situ.  Curr Protoc Cell Biol  2020 12;89(1):e115. doi:10.1002/cpcb.115
  10. Green KJ, Roth-Carter Q, Niessen CM, Nichols SA  Tracing the Evolutionary Origin of Desmosomes.  Curr Biol  2020 05 18;30(10):R535-R543. pii:S0960-9822(20)30417-6
  11. Broussard JA, Jaiganesh A, Zarkoob H, Conway DE, Dunn AR, Espinosa HD, Janmey PA, Green KJ  Scaling up single-cell mechanics to multicellular tissues - the role of the intermediate filament-desmosome network.  J Cell Sci  2020 03 16;133(6). pii:jcs228031
  12. Green KJ, Jaiganesh A, Broussard JA  Desmosomes:  Essential contributors to an integrated intercellular junction network.  F1000Res  2019;8. pii:F1000 Faculty Rev-2150
  13. Arnette CR, Roth-Carter QR, Koetsier JL, Broussard JA, Burks HE, Cheng K, Amadi C, Gerami P, Johnson JL, Green KJ  Keratinocyte cadherin desmoglein 1 controls melanocyte behavior through paracrine signaling.  Pigment Cell Melanoma Res  2020 03;33(2):305-317. doi:10.1111/pcmr.12826
  14. Cohen-Barak E, Godsel LM, Koetsier JL, Hegazy M, Kushnir-Grinbaum D, Hammad H, Danial-Farran N, Harmon R, Khayat M, Bochner R  et al.  The Role of Desmoglein 1 in Gap Junction Turnover Revealed through the Study of SAM Syndrome.  J Invest Dermatol  2020 03;140(3):556-567.e9. pii:S0022-202X(19)33151-3
  15. Elliott PM, Anastasakis A, Asimaki A, Basso C, Bauce B, Brooke MA, Calkins H, Corrado D, Duru F, Green KJ  et al.  Definition and treatment of arrhythmogenic cardiomyopathy: an updated expert panel report.  Eur J Heart Fail  2019 08;21(8):955-964. doi:10.1002/ejhf.1534
  16. Valenzuela-Iglesias A, Burks HE, Arnette CR, Yalamanchili A, Nekrasova O, Godsel LM, Green KJ  Desmoglein 1 Regulates Invadopodia by Suppressing EGFR/Erk Signaling in an Erbin-Dependent Manner.  Mol Cancer Res  2019 05;17(5):1195-1206. doi:10.1158/1541-7786.MCR-18-0048
  17. Maruthappu T, Posafalvi A, Castelletti S, Delaney PJ, Syrris P, O'Toole EA, Green KJ, Elliott PM, Lambiase PD, Tinker A  et al.  Loss-of-function desmoplakin I and II mutations underlie dominant arrhythmogenic cardiomyopathy with a hair and skin phenotype.  Br J Dermatol  2019 05;180(5):1114-1122. doi:10.1111/bjd.17388
  18. Yang R, Broussard JA, Green KJ, Espinosa HD  Techniques to stimulate and interrogate cell-cell adhesion mechanics.  Extreme Mech Lett  2018 Apr;20:125-139. doi:10.1016/j.eml.2017.12.002
  19. Kam CY, Dubash AD, Magistrati E, Polo S, Satchell KJF, Sheikh F, Lampe PD, Green KJ  Desmoplakin maintains gap junctions by inhibiting Ras/MAPK and lysosomal degradation of connexin-43.  J Cell Biol  2018 09 03;217(9):3219-3235. doi:10.1083/jcb.201710161
  20. Mohamad J, Sarig O, Godsel LM, Peled A, Malchin N, Bochner R, Vodo D, Rabinowitz T, Pavlovsky M, Taiber S  et al.  Filaggrin 2 Deficiency Results in Abnormal Cell-Cell Adhesion in the Cornified Cell Layers and Causes Peeling Skin Syndrome Type A.  J Invest Dermatol  2018 08;138(8):1736-1743. pii:S0022-202X(18)31969-9
  21. Polivka L, Hadj-Rabia S, Bal E, Leclerc-Mercier S, Madrange M, Hamel Y, Bonnet D, Mallet S, Lepidi H, Ovaert C  et al.  Epithelial barrier dysfunction in desmoglein-1 deficiency.  J Allergy Clin Immunol  2018 08;142(2):702-706.e7. pii:S0091-6749(18)30616-X
  22. Nekrasova O, Harmon RM, Broussard JA, Koetsier JL, Godsel LM, Fitz GN, Gardel ML, Green KJ  Desmosomal cadherin association with Tctex-1 and cortactin-Arp2/3 drives perijunctional actin polymerization to promote keratinocyte delamination.  Nat Commun  2018 03 13;9(1):1053. doi:10.1038/s41467-018-03414-6
  23. Vodo D, O'Toole EA, Malchin N, Lahav A, Adir N, Sarig O, Green KJ, Smith FJD, Sprecher E  Striate palmoplantar keratoderma resulting from a missense mutation in DSG1.  Br J Dermatol  2018 09;179(3):755-757. doi:10.1111/bjd.16320
  24. Broussard JA, Green KJ  Research Techniques Made Simple: Methodology and Applications of Förster Resonance Energy Transfer (FRET) Microscopy.  J Invest Dermatol  2017 11;137(11):e185-e191. pii:S0022-202X(17)32952-4
  25. Quinlan RA, Schwarz N, Windoffer R, Richardson C, Hawkins T, Broussard JA, Green KJ, Leube RE  A rim-and-spoke hypothesis to explain the biomechanical roles for cytoplasmic intermediate filament networks.  J Cell Sci  2017 Oct 15;130(20):3437-3445. doi:10.1242/jcs.202168
  26. Rübsam M, Broussard JA, Wickström SA, Nekrasova O, Green KJ, Niessen CM  Adherens Junctions and Desmosomes Coordinate Mechanics and Signaling to Orchestrate Tissue Morphogenesis and Function: An Evolutionary Perspective.  Cold Spring Harb Perspect Biol  2018 11 01;10(11). pii:a029207
  27. Najor NA, Fitz GN, Koetsier JL, Godsel LM, Albrecht LV, Harmon R, Green KJ  Epidermal Growth Factor Receptor neddylation is regulated by a desmosomal-COP9 (Constitutive Photomorphogenesis 9) signalosome complex.  Elife  2017 09 11;6. doi:10.7554/eLife.22599
  28. Broussard JA, Yang R, Huang C, Nathamgari SSP, Beese AM, Godsel LM, Hegazy MH, Lee S, Zhou F, Sniadecki NJ  et al.  The desmoplakin-intermediate filament linkage regulates cell mechanics.  Mol Biol Cell  2017 Nov 07;28(23):3156-3164. doi:10.1091/mbc.E16-07-0520
  29. Eskin-Schwartz M, Drozhdina M, Sarig O, Gat A, Jackman T, Isakov O, Shomron N, Samuelov L, Malchin N, Peled A  et al.  Epidermolytic Ichthyosis Sine Epidermolysis.  Am J Dermatopathol  2017 Jun;39(6):440-444. doi:10.1097/DAD.0000000000000674
  30. Jones JC, Kam CY, Harmon RM, Woychek AV, Hopkinson SB, Green KJ  Intermediate Filaments and the Plasma Membrane.  Cold Spring Harb Perspect Biol  2017 Jan 03;9(1). pii:a025866
  31. Samuelov L, Li Q, Bochner R, Najor NA, Albrecht L, Malchin N, Goldsmith T, Grafi-Cohen M, Vodo D, Fainberg G  et al.  SVEP1 plays a crucial role in epidermal differentiation.  Exp Dermatol  2017 05;26(5):423-430. doi:10.1111/exd.13256
View all publications by Dr. Kathleen J. Green listed in the National Library of Medicine (PubMed).