Read about Yuki Aoi's et al., Molecular Cell 2020 paper from the Shilatifard laboratory.
Christie Sze has been chosen for the Eighth Annual Driskill Scholar Award. Congratulations Christie!
Northwestern University Feinberg School of Medicine's Breakthroughs Podcast features Ali Shilatifard.
The regulation of gene expression by RNA polymerase II is essential for development and differentiation, and its misregulation contributes to the pathogenesis of many forms of cancers. The goal of our laboratory is to define the molecular mechanisms underlying cancer pathogenesis and to identify potential targets for therapy. These studies have been done through detailed understanding of proteins and protein complexes that regulate chromatin modifications, transcriptional initiation, and transcriptional elongation. Several of such findings from our lab our now under clinical studies for the treatment of bladder cancer and pediatric brain tumors.
“Northwestern isn’t just a compass point on a map. Here, it’s a mindset. A Northwestern Direction is a journey that each one of us creates and defines as our own. There’s always a new adventure, a new idea, and a new discovery—no matter what path you pursue.”