Meet the Burridge lab team members. We welcome requests for information about our work and collaboration opportunities.
Paul Burridge, PhD
Assistant Professor, Department of Pharmacology and Center for Pharmacogenomics
Dr. Burridge is an assistant professor in the Department of Pharmacology at Northwestern University Feinberg School of Medicine and a founding faculty member of the Center for Pharmacogenomics. Dr. Burridge began his career in genomics and bioinformatics at the Sanger Institute working on the human and mouse genome projects. He completed a PhD in Human Stem Cell Biology at the University of Nottingham before pursuing postdoctoral fellowships at Johns Hopkins University in Pediatric Oncology and then at Stanford University in Cardiology before becoming an Instructor in Cardiovascular Medicine at Stanford. For more than 15 years, Dr. Burridge has worked on the applications of human pluripotent stem cells (both hESC and hiPSC), concentrating on culture and differentiation methodologies, regenerative medicine, and disease modeling, specifically the pharmacogenomic and molecular mechanisms of chemotherapy-induced cardiomyopathy and heart failure. Dr. Burridge is the recipient of the NIH NHLBI Pathway to Independence Award and a Fellow of the American Heart Association in Genomic and Precision Medicine.
View Northwestern University Feinberg School of Medicine faculty profile
Malorie Blancard, PhD
Training: Malorie earned her PhD in Human Genetics from Sorbonne University in Paris in 2018. There, she focused on the identification of new variants causing cardiac arrhythmias with a risk of sudden death by using exome sequencing analysis and functional studies on calcium channels. She is interested to pursue her career on rare cardiac arrhythmias using other relevant technologies such as genome sequencing and hiPSC. She started her first postdoctoral research in Burridge Lab in February of 2019 and works on hiPSC models of sudden cardiac death.
Hananeh Fonoudi, PhD
Training: Hananeh earned her PhD in Stem Cells and Developmental Biology from the St. Vincent’s Clinical School of Medicine at the University of New South Wales, Sydney, Australia. During her PhD work she studied the genetics of hypoplastic left heart syndrome (HLHS) using human induced pluripotent stem cells under supervision of Dr. Richard Harvey at the Victor Chang Cardiac Research Institute. She joined Burridge lab at Northwestern University in February 2019 and works on human cardiac organoids and modeling pediatric congenital heart disease.
Mariam Jouni, PhD
Mariam earned her PhD. in Electrophysiology and Stem cell biology in 2015 from the University of Nantes in France. During her PhD, she worked at L'unité de recherche de l'institut du thorax and got trained to perform electrophysiological characterization of hiPSC-derived cardiomyocytes. She was further interested in translational medicine, so following her PhD., she started her first postdoctoral fellowship at UHN, Toronto General Hospital under the supervision of Dr. Michael Laflamme. She joined Burridge Lab at Northwestern University in July 2018 and works on novel variants causing long QT syndrome.
Davi Lyra-Leite, PhD
Davi earned his Ph.D. in Biomedical Engineering from the University of Southern California in 2019 under the supervision of Dr. Megan McCain. During his doctoral training, he studied the role of matrix rigidity, matrix protein composition, and tissue architecture on the regulation of mitochondrial function and structure in cardiomyocytes. He joined the Burridge lab in November 2019 and is interested in the role of metabolism in cardiac development and pathophysiology.
Tarek Mohamed, PhD
Tarek Mohamed earned his PhD in pharmacogenomics from the School of Pharmacy, Eberhard Karls University of Tuebingen in Germany. While earning his PhD, he worked as an early-stage researcher within a European Union sponsored research programme entitled “FightingDrugFailure” as a part of Marie Curie Initial Training Network (ITN) at the Dr. Margarete Fischer-Bosch institute of clinical pharmacology in Stuttgart, Germany. He started his postdoctoral studies in Burridge Lab at Northwestern University in September of 2015.
Mennat Gharib, BS
Mennat graduated magna cum laude from the University of Illinois Chicago in May 2019 with a BS in Biological Sciences. As an undergraduate she worked as a research assistant in the Molecular, Cell and Developmental Biology Research group in the Dept. of Biological Sciences at UIC as well as in the Dept of Psychiatry at the UIC College of Medicine. In the future, she hopes to pursue a medical career while still being actively involved in research.
K. Ashley Fetterman, BA
PhD Student (DGP)
Ashley is a PhD student in the Driskill Graduate Program (DGP) at Northwestern. She received her BA in Biological Sciences from Mount Holyoke College. Before joining the Burridge lab, she worked in drug discovery and clinical research. She is focusing on calmodulinopathies, chemotherapy-induced arrhythmias, cardiomyocyte subtype specification, and maturation in the Burridge lab.
Emily Pinheiro, BA
MD/PhD Student (MSTP)
Emily is an MD/PhD student in the Medical Scientist Training Program and Driskill Graduate Program (DGP) at Northwestern University. She received her B.A. from the University of Illinois at Urbana-Champaign. Before joining the Burridge lab, she worked in clinical research with a focus on pharmacotherapy for pregnant women. Her research focuses on pluripotent stem cell modeling of vascular disease.
Marisol Romero Tejeda, AB
PhD Student (DGP)
Marisol is a PhD student in the Driskill Graduate Program (DGP) at Northwestern University. She received her AB in Human Developmental and Regenerative Biology from Harvard University. Before joining the Burridge lab, she worked as a technician at the Ragon Institute of MGH, MIT, and Harvard. She currently works on direct reprogramming.
Carly Weddle, BS
PhD Student (DGP)
Carly is a PhD student in the Driskill Graduate Program (DGP) at Northwestern, where she is studying hiPSC models of breast cancer. She received her BS in Biochemistry from Elon University while conducting research in analytical chemistry.
Conrad Epting, MD
Attending Physician, Critical Care and Cardiology, Associate Professor of Pediatrics and Pathology
Strategies to promote cell and tissue regeneration remain at the forefront of cardiovascular biology. I have a scientific background in myogenic stem cells and skeletal muscle regeneration. At Northwestern University, I spent some years studying myocardial targeting by pathogens, specifically T. cruzi, the leading cause of myocarditis and heart failure in endemic regions of Latin American. However, as a practicing cardiac intensivist, my research program has shifted to the study of pediatric heart failure. I am interested in the response of resident progenitor cells to aging and heart failure. We suspect an epigenetic basis for cardiac progenitor cell activation in patients with premature ventricular failure secondary to exposure from neurohormonal axis activation. In partnership with the pediatric cardiovascular surgeons we created a cardiac biorepository to further translational research across the institution. Through collaboration with the Burridge laboratory I hope to determine the differentiation potential of resident cardiac cell populations and optimize direct reprograming of primary cardiac fibroblasts. We hope that knowledge of the phenotype of resident cells and their reprograming potential will enable clinical cryobanking, ex vivo reprogramming, and in situ cell manipulation to extend the lives of children and young adults with progressive heart failure from cardiomyopathy and congenital heart disease. We have implementing the Fontan Futures Initiative to optimize atrial tissue cryopreservation and enable clinical grade biobanking on behalf of patients with single ventricle physiology who are likely to progress to end-stage heart failure through a generous endowment from the Mathews Center for Cellular Therapy at Northwestern Medicine.