Key Publications

- Sharma TT, Edassery SL, Rajinikanth N, Karra V, Bury MI, Sharma AK. Proteomic profiling of regenerated urinary bladder tissue in a non-human primate augmentation model. Sci Rep. 2024 Jul 9;14(1):15757. 

- Kim J, Bury MI, Kwon K, Yoo JY, Halstead NV, Shin HS, Li S, Won SM, Seo MH, Wu Y, Park DY, Kini M, Kwak JW, Madhvapathy SR, Ciatti JL, Lee JH, Kim S, Ryu H, Yamagishi K, Yoon HJ, Kwak SS, Kim B, Huang Y, Halliday LC, Cheng EY, Ameer GA, Sharma AK*, Rogers JA*. A wireless, implantable bioelectronic system for monitoring urinary bladder function following surgical recovery. Proc Natl Acad Sci U S A. 2024 Apr 2;121(14):e2400868121 Epub 2024 Mar 28.

- Ameer G, Keate R, Bury M, Mendez-Santos M, Gerena A, Goedegebuure M, Rivnay J, Sharma A. Cell-free biodegradable electroactive scaffold for urinary bladder regeneration. Res Sq [Preprint]. 2024 Jan 29:rs.3.rs-3817836. doi:

- Goedegebuure M, Bury M, Wang X, San Felice P, Cammarata F, Wang L, Sharma T, Rajinikanth N, Karra V, Siddha V, Sharma A*, Ameer GA.* biodegradable microgrooved and tissue mechanocompatible citrate-based scaffold improves bladder tissue regeneration. bioRxiv [Preprint]. 2024 Feb 18:2024.02.15.580554.

- Madhvapathy SR, Bury MI, Wang LW, Ciatti JL, Avila R, Huang Y, Sharma AK*, Rogers JA*. Miniaturized implantable temperature sensors for the long-term monitoring of chronic intestinal inflammation. Nat Biomed Eng. 2024 Mar 18.

- Bury MI, Fuller NJ, Wang X, Chan YY, Sturm RM, Oh SS, Sofer LA, Arora HC, Sharma TT, Nolan BG, Feng W, Rabizadeh RR, Barac M, Edassery SS, Goedegebuure MM, Wang LW, Ganesh B, Halliday LC, Seniw ME, Edassery SL, Mahmud NB, Hofer MD, McKenna KE, Cheng EY, Ameer GA, Sharma AK. Multipotent bone marrow cell-seeded polymeric composites drive long-term, definitive urinary bladder tissue regeneration. PNAS Nexus. 2024 Jan 30;3(2):pgae038.

- Gunasekaran M, Bury MI, Tiffany T. Sharma TT, Wang L, Fuller NJ, Krishnan ST, Kaushal S,  Sharma AK. Multipotent human neonatal cardiac-derived mesenchymal stem cells modulate ileitis in vivo. Advanced Therapeutics 06 July 2023

- Sharma TT, Rabizadeh RR, Prabhakar VS, Bury MI, Sharma AK. Evolving Experimental Platforms to Evaluate Ulcerative Colitis. Adv Biol (Weinh). 2022 Oct;6(10):e2200018.

- Chan YY, Bury MI, Fuller NJ, Nolan BG, Gerbie EY, Hofer MD, Sharma AK. Effects of Anti-Inflammatory Nanofibers on Urethral Healing. Macromol Biosci. 2021 May;21(5):e2000410.

- Bury MI, Fuller NJ, Clemons TD, Sturm RM, Morrrison CD, Lisy-Snow DC, Nolan BG, Tarczynski C, Ayello EMT, Boyce A, Muckian B, Ahmad N, Hunter CJ, Karver MR, Stupp SI, Sharma AK. Self-assembling nanofibers inhibit inflammation in a murine model of Crohn's-disease-like ileitis. Adv Therap. 2000274. [Epub 2021 Feb 5]

- Yura Gerbie E, Bury MI, Chan YY, Morey AF, Sharma AK, Hofer MD. Testosterone and Estrogen Repletion in a Hypogonadal Environment Improves Post-operative Angiogenesis. Urology. 2021 Jun;152:9.e1-9.e6.

- Bury MI, Fuller NJ, Sturm RM, Rabizadeh RR, Nolan BG, Barac N, Edassery SS, Chan YY, Sharma AK. The effects of bone marrow stem and progenitor cell seeding on urinary bladder tissue regeneration. Sci Rep. 2021 Jan 27;11(1):2322.

- Yura EM, Bury MI, Chan Y, Morey AF, Sharma AK, Hofer MD. Reversing urethral hypovascularity through testosterone and estrogen supplementation. Urology 2020 Dec;146:242-247.

- Chan YY, Bury MI, Yura EM, Hofer MD, Cheng EY, Sharma AK. The current state of tissue engineering in the management of hypospadias. Nat Rev Urol. 2020 Mar;17(3):162-175.

- Iannaccone PM, Galat V, Bury MI, Ma YC, Sharma AK. The utility of stem cells in pediatric urinary bladder regeneration. Pediatr Res. 2018 Jan;83(1-2):258-266.

- Liu JS, Bury MI, Fuller NJ, Sturm RM, Ahmad N, Sharma AK. Bone marrow stem/progenitor cells attenuate the inflammatory milieu following substitution urethroplasty. Sci Rep. 2016 Oct 20;6:35638.

- Hofer MD, Morey AF, Sheth K, Tausch TJ, Siegel J, Cordon BH, Bury MI, Cheng EY, Sharma AK, Gonzalez CM, Kaplan WE, Kavoussi NL, Klein A, Roehrborn CG. Low serum testosterone level predisposes to artificial urinary sphincter cuff erosion. Urology. 2016 Jul 20. pii: S0090-4295(16)30422-8.

- Snow-Lisy DC, Diaz EC, Bury MI, Fuller NJ, Hannick JH, Ahmad N, Sharma AK. The role of genetically modified mesenchymal stem cells in urinary bladder regeneration. PLoS One. 2015 Sep 23; 10(9): e0138643.

- Bury MI, Fuller NJ, Wethekam L, Sharma AK. Bone marrow stem and progenitor cells facilitate urinary bladder regeneration by attenuating tissue inflammatory response. Cent European J Urol. 2015; 68(1): 115-120.

- Hofer MD, Cheng EY, Bury MI, Xu W, Hong SJ, Kaplan WE, Sharma AK. Androgen supplementation in rats increases the inflammatory response and prolongs urethral healing. Urology. 2015 Mar;85(3):691-7.

- Sharma AK, Cheng EY. Growth factor and small molecule influence on urological tissue regeneration utilizing cell seeded scaffolds. Adv Drug Deliv Rev. 2014 Nov 15. pii: S0169-409X(14)00271-3.

- Bury MI, Fuller NJ, Meisner JW, Hofer MD, Webber MJ, Chow LW, Prasad S, Thaker H, Yue X, Menon VS, Diaz EC, Stupp SI, Cheng EY, Sharma AK. The promotion of functional urinary bladder regeneration using anti-inflammatory nanofibers. Biomaterials. 2014 Nov;35(34):9311-9321.

- Hofer MD, Cheng EY, Bury MI, Park E, Xu W, Hong SJ, Kaplan WE, Sharma AK. Analysis of primary urethral wound healing in the rat. Urology. 2014 Jul;84(1):246.e1-7.

- Pokrywczynska M, Adamowicz J, Sharma AK, Drewa T. Human urinary bladder regeneration through tissue engineering - an analysis of 131 clinical cases. Exp Biol Med (Maywood). 2014 Mar;239(3):264-71.

- Sharma AK. Is a functional urinary bladder attainable through current regenerative medicine strategies? Cent European J Urol. 2013;66(2):207-8.

- Thaker H, Sharma AK. Regenerative medicine based applications to combat stress urinary incontinence. World J Stem Cells. 2013 Oct 26;5(4):112-123.

- Sharma AK, Bury MI, Fuller NJ, Marks AJ, Kollhoff DM, Rao MV, Hota PV, Matoka DJ, Edassery SL, Thaker H, Sarwark JF, Janicki JA, Ameer GA, Cheng EY. Cotransplantation with specific populations of spina bifida bone marrow stem/progenitor cells enhances urinary bladder regeneration. Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):4003-8.

- Thaker H, Sharma AK. Engaging stem cells for customized tendon regeneration. Stem Cells Int. 2012;2012:309187.

- Drewa T, Adamowicz J, Sharma A. Tissue engineering for the oncologic urinary bladder. Nat Rev Urol. 2012 Oct;9(10):561-72.

- Sharma AK, Bury MI, Fuller NJ, Rozkiewicz DI, Hota PV, Kollhoff DM, Webber MJ, Tapaskar N, Meisner JW, Lariviere PJ, Destefano S, Wang D, Ameer GA, Cheng EY. Growth factor release from a chemically modified elastomeric poly(1,8-octanediol-co-citrate) thin film promotes angiogenesis in vivo. J Biomed Mater Res A. 2012 Mar;100(3):561-70.

- Kollhoff DM, Cheng EY, Sharma AK. Urologic applications of engineered tissue. Regen Med. 2011 Nov;6(6):757-65.

- Sharma AK. An examination of regenerative medicine-based strategies for the urinary bladder. Regen Med. 2011 Sep;6(5):583-98.

- Sharma AK, Bury MI, Marks AJ, Fuller NJ, Meisner JW, Tapaskar N, Halliday LC, Matoka DJ, Cheng EY. A Non-Human Primate Model for Urinary Bladder Regeneration Utilizing Autologous Sources of Bone Marrow Derived Mesenchymal Stem Cells. Stem Cells. 2011 Feb;29(2):241-50. Epub 2010 Nov 23.

- Chow LW, Bitton R, Webber MJ, Carvajal D, Shull KR, Sharma AK, Stupp SI. A bioactive self-assembled membrane to promote angiogenesis. Biomaterials. 2011 Feb;32(6):1574-82. Epub 2010 Nov 18.

- Sharma AK, Hota PV, Matoka DJ, Fuller NJ, Jandali D, Thaker H, Ameer GA, Cheng EY. Urinary bladder smooth muscle regeneration utilizing bone marrow derived mesenchymal stem cell seeded elastomeric poly(1,8-octanediol-co-citrate) based thin films. Biomaterials. 2010 Aug;31(24):6207-17. Epub 2010 May 21.

- Sharma AK, Fuller NJ, Sullivan RR, Fulton N, Hota PV, Harrington DA, Villano J, Hagerty JA, Cheng EY. Defined populations of bone marrow derived mesenchymal stem and endothelial progenitor cells for bladder regeneration. J Urol. 2009 Oct;182(4 Suppl):1898-905. Epub 2009 Aug 20.

- Sharma AK, Donovan JL, Hagerty JA, Sullivan RR, Edassery SL, Harrington DA, Cheng EY. Do current bladder smooth muscle cell isolation procedures result in a homogeneous cell population? Implications for bladder tissue engineering. World J Urol. 2009 Oct;27(5):687-94. Epub 2009 Feb 21.

- Sharma A, Belna J, Espat J, Rodriguez G, Cannon VT, Hurteau JA. Effects of omega-3 fatty acids on components of the transforming growth factor beta-1 pathway: implication for dietary modification and prevention in ovarian cancer. Am J Obstet Gynecol. 2009 May;200(5):516.e1-6. Epub 2009 Mar 9.

- Bedi R, Du J, Sharma AK, Gomes I, Ackerman SJ. Human C/EBP-epsilon activator and repressor isoforms differentially reprogram myeloid lineage commitment and differentiation. Blood. 2009 Jan 8;113(2):317-27. Epub 2008 Oct 2.

- Harrington DA, Sharma AK, Erickson BA, Cheng EY. Bladder tissue engineering through nanotechnology. World J Urol. 2008 Aug;26(4):315-22. Epub 2008 Jun 7.

- Sharma A, Belna J, Logan J, Espat J, Hurteau JA. The effects of Omega-3 fatty acids on growth regulation of epithelial ovarian cancer cell lines. Gynecol Oncol. 2005 Oct;99(1):58-64.

- Gussin HA, Sharma AK, Elias S. Culture of cells from maternal circulation, in conditions favoring fetal endothelial cell expansion, does not facilitate the preferential expansion of circulating fetal cells. Fetal Diagn Ther. 2005 Jan-Feb;20(1):64-9.

- Gussin HA, Sharma AK, Elias S. Culture of endothelial cells isolated from maternal blood using anti-CD105 and CD133. Prenat Diagn. 2004 Mar;24(3):189-93.

- Sharma AK, Nelson MC, Brandt JE, Wessman M, Mahmud N, Weller KP, Hoffman R. Human CD34(+) stem cells express the hiwi gene, a human homologue of the Drosophila gene piwi. Blood. 2001 Jan 15;97(2):426-34.