On the forefront of regenerative medicine.
The Sharma Laboratory
Our research focus is regenerative medicine, specifically tissue engineering and biomaterials in urologic, gastrointestinal and vascular regeneration models.
We study the regenerative applications of combining novel elastomeric scaffolds with specific stem and progenitor cell populations, and utilize nanomolecules and small molecules to customize microenvironments suited to specific regenerative processes.
The Latest From the Lab
Sensor Monitors Bladder Fullness
At A Glance
- A collaboration of researchers at Northwestern University developed a wireless implantable device that can monitor bladder filling and emptying in real time and send data to a smartphone.
- With further development, this type of device could help monitor recovery after bladder surgery and aid patients who have compromised bladder function.
Synthetic ‘bladder patch’ promotes tissue regeneration, restores function
A research team led by SQI member Arun Sharma has developed a synthetic, flexible “bladder patch” that outperformed the current standard surgery for severe bladder dysfunction in a long-term, large-animal model — the last step before beginning clinical trials.
Novel injectable therapy shows promise in treating Crohn’s disease
A team of Simpson Querrey Institute (SQI) researchers led by Arun Sharma has demonstrated that a direct injection of anti-inflammatory peptide amphiphiles (PAs) into intestinal lesions can reduce lesion size and inflammation in an animal model of Crohn’s disease, a chronic condition that is notoriously difficult to treat.