Research
Our research focus is regenerative medicine, specifically tissue engineering and biomaterials in urologic, gastrointestinal and vascular regeneration models.
We study the regenerative applications of combining novel elastomeric scaffolds with specific stem and progenitor cell populations, and utilize nanomolecules and small molecules to customize microenvironments suited to specific regenerative processes.
Our goals are translational - we work closely with our clinical partner, Dr Earl Cheng, MD, and collaborate across multiple disciplines. (View Collaborations)
Key Publications
"Effects of anti-inflammatory nanofibers on urethral healing." (Macromolecular Bioscience)
"Self-assembling nanofibers inhibit inflammation in a murine model of Crohn's-disease-like ileitis." (Advanced Therapeutics)
"The current state of tissue engineering in the management of hypospadias." (Nature Reviews Urology)
"The promotion of functional urinary bladder regeneration using anti-inflammatory nanofibers." (Biomaterials)
News and Awards
"Novel injectable therapy shows promise in treating Crohn's disease"(News, Simpson Querrey Institute)
"Promising Approach to Urinary Bladder Tissue Regeneration"
(News, Ann & Robert H. Lurie Children's Hospital of Chicago)
Society for Biomaterials
2021 Annual Meeting
Abstracts accepted for presentation:
Bury et al. Supramolecular Nanomolecules Abrogate Inflammation in a Mouse Model of Ulcerative Colitis.
Nguyen et al. Characterization of a Highly Elastic, Biodegradable, Citrate-Based Elastomer for Tissue Engineering.
Wang et al. Characterization of a Tubular Synthetic Elastomeric Scaffold for the Potential Use in Urethral Substitution.
Falk Medical Research Trust Award
(News, Ann & Robert H. Lurie Children's Hospital of Chicago)
Dr Arun Sharma received the Catalyst Research Award from the Dr Ralph and Marian Falk Medical Research Trust.
Collaborative projects discussed in Dr Guillermo Ameer's article, "Emerging Field of Regenerative Engineering Potential Game Changer for Tissue, Organ Repair"
(R&D Magazine).
Hartwell Biomedical Research Award
(Hartwell Foundation Announcement)
Dr Arun Sharma, "Anti-inflammatory Nanomolecules for the Treatment of Crohn's Disease"
The Hartwell Foundation grants awards to individuals for innovative and cutting-edge biomedical applied research that will potentially benefit children.
"Northwestern Scientists Win Hartwell Research Awards"(News, Northwestern University)
