Northwestern University Feinberg School of Medicine

Krainc Laboratory

About Us

The overarching goal of our research is to define key molecular pathways in the pathogenesis of neurodegeneration. We have focused on pathogenic mechanisms that occur across neurodegenerative disorders such as accumulation and deficient degradation of aggregation-prone proteins and mitochondrial dysfunction. As a general strategy, our lab is studying rare genetic diseases, such as Huntington’s and genetic forms for Parkinson’s, in particular those with mutations in genes that play a role in these common pathogenic pathways (e.g. PINK1, LRRK2, Parkin, ATP13A2, DJ-1, Gaucher) with a goal of identifying converging pathways and specific targets for therapeutic development in neurodegeneration.

Contact Us

The Krainc Lab welcomes your questions and comments. For general feedback and inquries, please contact us for more information via our office information below.

Elizabeth Smart
Program Assistant to the Office of the Chairman

303 East Chicago Avenue, Ward 12-140
Chicago, Illinois  60611-4296
Phone: 312-503-3936