Northwestern University Feinberg School of Medicine

Alan Hauser Laboratory

Lab Members

Meet the Hauser Lab team members. We welcome requests for information about our work and collaboration opportunities.

Principal Investigator

 
Alan Hauser

Alan Hauser, MD/PhD
ahauser( at )northwestern.edu
Professor in Microbiology-Immunology and Medicine-Infectious Diseases
312-503-1044
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Our laboratory investigates the pathogenesis of the multidrug resistant gram-negative bacteria Pseudomonas aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae. We focus on virulence factors such as the type III secretion, an apparatus that injects toxins directly into host cells. Other interests are the use of genomic approaches for the identification of novel virulence determinants and the development of novel translational approaches to treat bacterial infections. Our studies utilize a broad range of techniques, including molecular and cellular assays as well as animal models and epidemiologic studies on human populations.

Research Collaborators

 
Larry Kociolek

Larry Kociolek, MD
larry-kociolek( at )northwestern.edu
Instructor in Pediatrics-Infectious Diseases
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My research interests are in the areas of healthcare epidemiology and infection prevention and control, particularly Clostridium difficile infections. I am exploring various aspects of C. difficile infection, including clinical and molecular epidemiology, antibiotic resistance, and host immune response.

Egon Ozer

Egon Ozer, MD/PhD
e-ozer( at )northwestern.edu
Assistant Professor in Medicine-Infectious Diseases
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My research is focused on uncovering mechanisms of bacterial pathogenesis in Pseudomonas aeruginosa infection and other clinically relevant bacterial diseases. We are using comparative bacterial genomics to identify new genes and other factors that contribute to worse outcomes in patients infected with these bacteria.

 
MaulinSoneji, MD

Maulin Soneji, MD
maulin.soneji( at )northwestern.edu
MD Fellow

I completed medical school at Saint Louis University School of Medicine and then completed a residency in Internal Medicine and Pediatrics at Loma Linda University. I joined the Hauser Lab in August of 2016 during my second year of fellowship. My research focuses on genomic characterization of Pseudomonas aeruginosa from the lungs of patients with Cystic Fibrosis with the goal of evaluating how different genetic traits may lead to non-eradication of Pseudomonas aeruginosa.

Postdoctoral Fellows

 
Jonathan Allen

Jonathan Allen, PhD
jonathan.allen( at )northwestern.edu
Postdoctoral Research Fellow

My research focuses on the pathogenesis of Pseudomonas aeruginosa. I helped implement an innovative genomics-based approach to identify novel virulence determinants in the accessory genome of this important pathogen. I am currently investigating the role of several of these factors (identified in our screen) to determine their specific pathogenic function. I enjoy playing soccer and basketball, and finding the best whiskey bars Chicago has to offer.

KellyBachta, MD/PhD

Kelly Bachta, MD/PhD
kelly.bachta( at )northwestern.edu
Postdoctoral Fellow

Following my MD/PhD at the University of Chicago, I completed a residency in Internal Medicine at the University of Washington in Seattle followed by an Infectious Disease Fellowship at Massachusetts General Hospital in Boston. I moved back to Chicago in July of 2016 as an instructor in the Infectious Diseases Division and a post-doctoral fellow in the Hauser laboratory. My research focuses on understanding the pathogenesis of Pseudomonas aeruginosa bacteremia and understanding in vivo infection dynamics. In my free time, I enjoy cheering for my alma mater, the University of Maryland (GO TERPS!), a good local microbrew, and spending time with my husband and daughters re-exploring the windy city that we all love.

 
TravisKochan, PhD

Travis Kochan, PhD
travis.kochan( at )northwestern.edu
Postdoctoral Fellow

I earned my bachelor’s degree in 2010 from Wayne State University in Detroit, Michigan. I worked as a technician for ~3 years in Dr. Suzanne Dawid's lab at the University of Michigan studying the regulation of bacteriocin production in Streptococcus pneumoniae. I then started my graduate training in 2013 at the University of Michigan. I completed my thesis work investigating the role of calcium in germination of Clostridium difficile spores in June 2018. I moved from Ann Arbor to Chicago to join the Hauser lab as a Postdoctoral Fellow in August 2018. My research in the Hauser lab focuses on identification and characterization of accessory genomic elements that are associated with pathogenesis in the opportunistic pathogen, Klebsiella pneumoniae.

TimTurner, PhD

Tim Turner, PhD
tim( at )northwestern.edu
Postdoctoral Fellow

I earned my Bachelor of Science degree in Family and Consumer Sciences at Illinois State University in 2011 and my Ph.D. in Food Microbiology at the University of Illinois at Urbana-Champaign in 2016. I have investigated a variety of microbiological areas of research including treatment of parasitic Leishmania spp. and engineering of yeast for renewable chemical production. I joined the Hauser lab as a Postdoctoral Fellow in October 2016 studying pathogenic Pseudomonas spp. In my free time, I enjoy telling my wife about all the cute dogs I saw on my walk to/from the lab.

Graduate Students

 
Mallory Agard

Mallory Agard
mallory.agard( at )northwestern.edu
Graduate Student (DGP)

I earned my bachelor’s degree in 2009 from University of Wisconsin-Madison in Bacteriology. I then earned a master’s degree from Tulane University in 2012 in Medical Microbiology and Immunology. I joined the Hauser lab in 2014 to identify novel virulence determinants in contemporary clinical Acinetobacter baumannii isolates using comparative genomics approaches. In my free time, I love discovering new music and enjoying wilderness activities such as rock climbing, backpacking, kayaking, and canoeing.

NathanPincus

Nathan Pincus
nathan.pincus( at )northwestern.edu
Graduate Student

I earned my BS in Molecular and Cellular Biology from the University of Puget Sound in 2013. I started in the Medical Scientist Training Program at Northwestern University in 2014 and joined the Hauser lab in 2016. My research focuses on using comparative genomics to uncover factors important in determining disease severity of Pseudomonas aeruginosa infections in humans.

 
Angelica Zhang

Angelica Zhang
angelica-zhang( at )fsm.northwestern.edu
Graduate Student

I work on the Pseudomonas aeruginosa Type III secreted protein ExoU and its cytotoxic effects on mammalian cells. Some say I'm a decent classical musician. I also know magic.

Undergraduate Students

 
OliviaPura

Olivia Pura
OliviaPura2020( at )u.northwestern.edu
Undergraduate Research Assistant

My work focuses on analyzing exoU and exoS strain prevalence in Pseudomonas aeruginosa isolated from healthcare facilities. I began my work in the Hauser Lab as a freshman in October of 2016. When not in lab, I enjoy going to concerts, picking up a new crafting hobby, or exploring the food scene in Chicago.

Research Staff

 
MeganMurphy

Megan Murphy
megan.murphy( at )northwestern.edu
Laboratory Manager

I received my B.S. in Ecology and Evolution from Yale University where my research focused on using phage therapy to counter infection by drug resistant Pseudomonas aeruginosa. I continue to pursue this interest with the Hauser Lab, as of June 2018. In my free time, I enjoy traveling and backpacking with my husband, one-year-old daughter, and golden retriever.