Investigating the pathogenesis of multidrug-resistant gram-negative bacteria.

Our laboratory investigates the pathogenesis of the multidrug resistant gram-negative bacteria Pseudomonas aeruginosa, Acinetobacter baumannii and Klebsiella pneumoniae. We focus on virulence factors such as the type III secretion system. Other interests are the use of genomic approaches for the identification of novel virulence determinants and the development of novel translational approaches to treat bacterial infections.