Publications

High throughput single cell long-read sequencing analyses of same-cell genotypes and phenotypes in human tumors (2023)
Cheng-Kai Shiau, Lina Lu, Rachel Kieser, Kazutaka Fukumura, Timothy Pan, Hsiao-Yun Lin, Jie Yang, Eric L. Tong, GaHyun Lee, Yuanqing Yan, Jason T. Huse, Gao R
Nature Communications, 14 (1): 4124

Anaplastic transformation in thyroid cancer revealed by single cell transcriptomics (2023)
Lu L, Wang JR,Lu L, Wang JR, Ying HC, Bai S, Yan Y, Shiau CK, Kieser Rachel K, Hu M, Zhao X, Wang J, Williams M, Zafereo M, Cabanillas M, Navin N, Lai S, Gao R
Journal of Clinical Investigation, 133 (11): e169653 

Delineating copy number and clonal substructure in human tumors from single cell transcriptomes (2021)
Gao R, Bai S, Henderson Y, Lin Y, Schalck A, Yan Y, Kumar T, Hu M, Davis A, Wang F, Shaitelman S, Wang R, Chen K, Moulder S, Lai S, Navin N
Nature Biotechnology, 39 (5): 599-608

SCOPIT: sample size calculations for single-cell sequencing experiments (2019)
Davis A, Gao R, Navin N
BMC Bioinformatics, 20 (1): 566

Multiclonal invasion in DCIS identified by topographic single cell DNA sequencing (2018)
Casasent A, Schalck A, Gao R, Sei E, Long A, Pangburn W, Casasent T, Meric-Bernstam F, Edgerton M, Navin N
Cell, 172: 205-217

Chemoresistance evolution in triple-negative breast cancer delineated by single cell sequencing (2018)
Kim C*, Gao R*, Sei E, Brandt R, Hartman J, Hatschek T, Crosetto N, Foukakis T, Navin N (* co-first authors)
Cell, 173:879-893

Tumor evolution: linear, branched, neutral or punctuated? (2017)
Davis A, Gao R, Navin N
BBA-Rev on Cancer, 1867 (2): 151-161

Single cell DNA sequencing reveals a late dissemination model in metastatic colorectal cancer (2017)
Leung M, Davis A, Gao R, Casasent A, Wang Y, Sei E, Vilar E, Maru D, Kopetz S, Navin N
Genome Res, 27: 1287-99

Punctuated copy number evolution and clonal stasis in triple-negative breast cancer (2016)
Gao R, Davis A, McDonald T, Sei E, Shi X, Wang Y, Tsai PC, Casasent A, Waters J, Zhang H, Meric-Bernstam F, Michor F and Navin N
Nat Genet, 48: 1119-30