HPV Activates the ATM DNA Damage ResponseHPV Activates both SMC-1 and H2AX throughout differentiation.HPV Activates the ATM DNA Damage ResponseHPV Activates both SMC-1 and H2AX throughout differentiation.
HPV Activates the ATM DNA Damage ResponseHPV Activates the ATM DNA Damage Response throughout its differentiation dependent lifecycleHPV Activates the ATM DNA Damage ResponseHPV Activates the ATM DNA Damage Response throughout its differentiation dependent lifecycle
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The mission of our laboratory is to conduct basic research on human papillomavirus pathogenesis and facilitate the development of effective treatments against cervical cancer.
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Recent Publications
Hong, S., Li, Y., Kaminski, P., Andrade, J., and Laimins, L.A. Pathogenesis of human papillomaviruses requires the ATR/p62 autophagy-related pathway. mBio. 2020 Aug 12;11(4):e01628-20. doi: 10.1128/mBio.01628-20.
Kaminski P, Hong S, Kono T, Hoover P, Laimins L. 1. Topoisomerase 2β Induces DNA Breaks To Regulate Human Papillomavirus Replication. mBio. 2021 Feb 9;12(1):e00005-21. doi: 10.1128/mBio.00005-21.
Gusho, E. Laimins L. Human Papillomaviruses Target the DNA Damage Repair and Innate Immune Response Pathways to Allow for Persistent Infection. Viruses 2021-1299070; doi: 10.3390/v13071390.
