The mission of our laboratory is to conduct basic research on human papillomavirus pathogenesis and facilitate the development of effective treatments against cervical cancer.
Mehta K, Gunasekharan V, Satsuka A, Laimins LA Human papillomaviruses activate and recruit SMC1 cohesin proteins for the differentiation-dependent life cycle through association with CTCF insulators. PLoS Pathog 2015 Apr;11(4):e1004763. doi:10.1371/journal.ppat.1004763
Hong S, Dutta A, Laimins LA The acetyltransferase Tip60 is a critical regulator of the differentiation-dependent amplification of human papillomaviruses.J Virol 2015 Apr;89(8):4668-75. doi:10.1128/JVI.03455-14