Publications
For a full list of our publications, please visit PubMed.
- Xu C, Chen G, Yu B, Sun B, Zhang Y, Zhang M, Yang Y, Xiao Y, Cheng SY, Li Y et al. TRIM24 Cooperates with Ras Mutation to Drive Glioma Progression through snoRNA Recruitment of PHAX and DNA-PKcs. Adv Sci (Weinh) 2024 Aug;11(29):e2400023. pii:2400023
- Song X, Tiek D, Miki S, Huang T, Lu M, Goenka A, Iglesia R, Yu X, Wu R, Walker M et al. RNA splicing analysis deciphers developmental hierarchies and reveals therapeutic targets in adult glioma. J Clin Invest 2024 Apr 25;134(11). pii:e173789
- Kim DR, Orr MJ, Yu X, Munshi HH, Wang A, Trudeau C, Kwong AJ, Cheng SY, Scheidt KA Synthesis and Structural Optimization of ATG4B Inhibitors for the Attenuation of Autophagy in Glioblastoma. ACS Med Chem Lett 2024 Feb 08;15(2):258-264. doi:10.1021/acsmedchemlett.3c00505
- Bhutada I, Khambati F, Cheng SY, Tiek DM, Duckett D, Lawrence H, Vogelbaum MA, Mo Q, Chellappan SP, Padmanabhan J CDK7 and CDK9 inhibition interferes with transcription, translation, and stemness, and induces cytotoxicity in GBM irrespective of temozolomide sensitivity. Neuro Oncol 2024 Jan 05;26(1):70-84. doi:10.1093/neuonc/noad143
- Sun MA, Yang R, Liu H, Wang W, Song X, Hu B, Reynolds N, Roso K, Chen LH, Greer PK et al. Repurposing Clemastine to Target Glioblastoma Cell Stemness. Cancers (Basel) 2023 Sep 18;15(18). pii:4619
- Goenka A, Song X, Tiek D, Iglesia RP, Lu M, Zeng C, Horbinski C, Zhang W, Hu B, Cheng SY Oncogenic long noncoding RNA LINC02283 enhances PDGF receptor A-mediated signaling and drives glioblastoma tumorigenesis. Neuro Oncol 2023 Sep 05;25(9):1592-1604. doi:10.1093/neuonc/noad065
- Zeng C, Song X, Zhang Z, Cai Q, Cai J, Horbinski C, Hu B, Cheng SY, Zhang W Dissection of transcriptomic and epigenetic heterogeneity of grade 4 gliomas: implications for prognosis. Acta Neuropathol Commun 2023 Aug 14;11(1):133. pii:133
- Cai Q, Zhang Z, Cui X, Zeng C, Cai J, Cai J, Wu K, Zhang X, Shi Y, Arvanitakis Z et al. PETCH-DB: a Portal for Exploring Tissue-specific and Complex disease-associated 5-Hydroxymethylcytosines. Database (Oxford) 2023 Jun 10;2023. pii:baad042
- Getu AA, Zhou M, Cheng SY, Tan M The mammalian Sterile 20-like kinase 4 (MST4) signaling in tumor progression: Implications for therapy. Cancer Lett 2023 Jun 01;563:216183. doi:10.1016/j.canlet.2023.216183
- Tiek D, Wells CI, Schröder M, Song X, Alamillo-Ferrer C, Goenka A, Iglesia R, Lu M, Hu B, Kwarcinski F et al. SGC-CLK-1: A chemical probe for the Cdc2-like kinases CLK1, CLK2, and CLK4. Curr Res Chem Biol 2023;3. pii:100045
- McCord M, Bartom E, Burdett K, Baran A, Eckerdt FD, Balyasnikova IV, McCortney K, Sears T, Cheng SY, Sarkaria JN et al. Modeling Therapy-Driven Evolution of Glioblastoma with Patient-Derived Xenografts. Cancers (Basel) 2022 Nov 09;14(22). pii:5494
- Goenka A, Cheng SY Targeting neddylation in cancer. Neuro Oncol 2022 Nov 02;24(11):1869-1870. doi:10.1093/neuonc/noac159
- Goenka A, Tiek DM, Song X, Iglesia RP, Lu M, Hu B, Cheng SY The Role of Non-Coding RNAs in Glioma. Biomedicines 2022 Aug 20;10(8). pii:2031
- Tiek DM, Erdogdu B, Razaghi R, Jin L, Sadowski N, Alamillo-Ferrer C, Hogg JR, Haddad BR, Drewry DH, Wells CI et al. Temozolomide-induced guanine mutations create exploitable vulnerabilities of guanine-rich DNA and RNA regions in drug-resistant gliomas. Sci Adv 2022 Jun 24;8(25):eabn3471. pii:eabn3471
- Iglesia RP, Prado MB, Alves RN, Escobar MIM, Fernandes CFL, Fortes ACDS, Souza MCDS, Boccacino JM, Cangiano G, Soares SR et al. Unconventional Protein Secretion in Brain Tumors Biology: Enlightening the Mechanisms for Tumor Survival and Progression. Front Cell Dev Biol 2022;10:907423. pii:907423
- Tiek D, Cheng SY DNA damage and metabolic mechanisms of cancer drug resistance. Cancer Drug Resist 2022;5(2):368-379. doi:10.20517/cdr.2021.148
- Tiek DM, Cheng SY New life for an old therapy: ELTD1 as a downstream target of angiogenesis. Neuro Oncol 2022 Mar 12;24(3):412-413. doi:10.1093/neuonc/noab286
- Yu B, Luo F, Sun B, Liu W, Shi Q, Cheng SY, Chen C, Chen G, Li Y, Feng H KAT6A Acetylation of SMAD3 Regulates Myeloid-Derived Suppressor Cell Recruitment, Metastasis, and Immunotherapy in Triple-Negative Breast Cancer. Adv Sci (Weinh) 2021 Oct;8(20):e2100014. pii:2100014
- Song L, Lin C, Gong H, Wang C, Liu L, Wu J, Tao S, Hu B, Cheng SY, Li M et al. Author Correction: miR-486 sustains NF-κB activity by disrupting multiple NF-κB-negative feedback loops. Cell Res 2021 Oct;31(10):1138. doi:10.1038/s41422-021-00549-y
- Cai J, Zeng C, Hua W, Qi Z, Song Y, Lu X, Li D, Zhang Z, Cui X, Zhang X et al. An integrative analysis of genome-wide 5-hydroxymethylcytosines in circulating cell-free DNA detects noninvasive diagnostic markers for gliomas. Neurooncol Adv 2021;3(1):vdab049. pii:vdab049
- Huang T, Cheng SY Targeting phospholipid metabolism for glioblastoma therapy. Neuro Oncol 2021 Mar 25;23(3):343-344. doi:10.1093/neuonc/noaa309
- Huang T, Yang Y, Song X, Wan X, Wu B, Sastry N, Horbinski CM, Zeng C, Tiek D, Goenka A et al. PRMT6 methylation of RCC1 regulates mitosis, tumorigenicity, and radiation response of glioblastoma stem cells. Mol Cell 2021 Mar 18;81(6):1276-1291.e9. doi:10.1016/j.molcel.2021.01.015
- Gao X, Xia X, Li F, Zhang M, Zhou H, Wu X, Zhong J, Zhao Z, Zhao K, Liu D et al. Circular RNA-encoded oncogenic E-cadherin variant promotes glioblastoma tumorigenicity through activation of EGFR-STAT3 signalling. Nat Cell Biol 2021 Mar;23(3):278-291. doi:10.1038/s41556-021-00639-4
- Goenka A, Tiek D, Song X, Huang T, Hu B, Cheng SY The Many Facets of Therapy Resistance and Tumor Recurrence in Glioblastoma. Cells 2021 Feb 24;10(3). pii:484
- Luo JH, Liu S, Tao J, Ren BG, Luo K, Chen ZH, Nalesnik M, Cieply K, Ma T, Cheng SY et al. Pten-NOLC1 fusion promotes cancers involving MET and EGFR signalings. Oncogene 2021 Feb;40(6):1064-1076. doi:10.1038/s41388-020-01582-8
- Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1. Autophagy 2021 Jan;17(1):1-382. doi:10.1080/15548627.2020.1797280