Northwestern University Feinberg School of Medicine

Shi-Yuan Cheng Lab

Lab Members


Meet the Lab team members. We welcome requests for information about our work and collaboration opportunities.

Principal Investigator


Shi-Yuan Cheng, PhD
Postdoctoral Fellowship, UCSD & LICR, Signal Transduction & Tumor Angiogenesis (1999)

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I love creative research and collaborating with colleagues within Northwestern and throughout the world. I also enjoy interacting with students and postdoctoral fellows. Outside my office, I enjoy my family, friendships and traveling.

Research Associate Professor


Bo Hu, PhD
Postdoctoral Fellowship, UCSD, Biochemistry (1997)

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I love what I do everyday in the lab and my office. I enjoy my family and traveling.

Postdoctoral Fellow

Xiao (Lisa) Song

Xiao (Lisa) Song, MD, PhD
PhD, Peking University (2016)

My work includes the study of epigenetic and epitranscriptomic regulation, onco-metabolism, and cancer stem cell biology in gliomas. I am also interested in establishing human iPSC-derived glioma models and improving the three-dimensional organoid culture system for studying glioma biology and screening anti-glioma therapeutics.


Anshika Goenka, PhD
PhD, Indian Institute of Technology, Kanpur (2017)

I am interested to study the mechanisms of long non-coding RNA (lncRNA) regulation in the oncogenesis of Glioblastoma (GBM) tumors using Glioma Stem Cell-like and adherent cell models of glioma. In particular, I am working to understand the regulation of a novel lncRNA in PDGFRA-signaling in GBM and the effect of their inter-regulation in driving tumorigenicity in the PDGFRA-driven cohort of GBM tumors. Also, I am interested to understand the mechanisms of resistance to the treatment drug, Temozolomide in clinically relevant PDX models of GBM.


Deanna Tiek, PhD
PhD, Georgetown University (2019)

I'm curious to learn how post-translational modifications, specifically PAR, regulate the localization and aggregation of RNA binding proteins in drug resistant GBM. Once better understood, it would be interesting to see how specific inhibitors of PTM regulators affect both RBP localization and splicing. In my free time I love exploring new restaurants/coffee shops, and baking/cooking!


Rebeca Iglesia, PhD
PhD, Universidade de São Paulo, Brazil (2017)

I am Rebeca Iglesia, bacharel in Biomedical Scien es and PhD in Cell Biology by University of São Paulo. My research englobes the study of celullar prion protein in the biology of glioblastoma stem cells, through its interaction with the chaperone heat shock organizing protein.

Graduate Student


Minghui Lu

I am from China and am currently a master's student in the Master of Biotechnology Program. I am interested in utilizing RNA-related therapy for cancer treatment. Besides lab, I love traveling and reading books.