Northwestern University Feinberg School of Medicine

Shi-Yuan Cheng Lab

Lab Members


Meet the Lab team members. We welcome requests for information about our work and collaboration opportunities.

Principal Investigator


Shi-Yuan Cheng, PhD
Postdoctoral Fellowship, UCSD & LICR, Signal Transduction & Tumor Angiogenesis (1999)

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I love creative research and collaborating with colleagues within Northwestern and throughout the world. I also enjoy interacting with students and postdoctoral fellows. Outside my office, I enjoy my family, friendships and traveling.

Research Associate Professor


Bo Hu, PhD
Postdoctoral Fellowship, UCSD, Biochemistry (1997)

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I love what I do everyday in the lab and my office. I enjoy my family and traveling.

Postdoctoral Fellow


Deanna Tiek, PhD
PhD, Georgetown University (2019)

I'm curious to learn how post-translational modifications, specifically PAR, regulate the localization and aggregation of RNA binding proteins in drug resistant GBM. Once better understood, it would be interesting to see how specific inhibitors of PTM regulators affect both RBP localization and splicing. In my free time I love exploring new restaurants/coffee shops, and baking/cooking!


Anshika Goenka, PhD
PhD, Indian Institute of Technology, Kanpur (2017)

I am interested to study the Immunosuppresive mechanisms known to be manifested in Glioblastoma (GBM) tumor. In particular, I am working to understand the polarisation of macrophages to a form which ensues immunosuppression in GBM. Also, my research work involves understanding the resistance mechanisms of Temozolomide treatment in clinically relevant models of GBM.

Xiao (Lisa) Song

Xiao (Lisa) Song, MD, PhD
PhD, Peking University (2016)

My work includes the study of epigenetic and epitranscriptomic regulation, onco-metabolism, and cancer stem cell biology in glioblastomas. I am also interested in improving the three-dimensional organoid culture system for studying glioma biology and screening anti-glioma therapeutics.​


Tianzhi Huang, PhD
PhD, Zhejiang University (2013)

My current research program is to understand molecular mechanisms of glioma stem cells (GSCs) including the regulation of Wnt Signaling by microRNAs, and the mechanisms of autophagy in control of GSC stemness and tumorigenicity.

Neurology Fellow

Bingli Wu

Bingli Wu, PhD
PhD, Shantou University (2011)

My main research interest is the application of both molecular experiments and bioinformatics, using of the biological data (microarray and RNA-seq) from our research group and public database, to analyze the biological functions, expression and regulation mechanisms, and cell signaling pathways of genes involved in the proliferation, invasion and metastasis of cancers.

Graduate Student


Namratha Sastry, BS
BS, West Virginia University (2012)

I'm studying how proteins that are differentially expressed in proneural versus mesenchymal glioma stem cells lead to aberrant signaling, and the consequences of this on tumorigenicity. When I'm not working in lab, I love outdoorsy activities (hiking, kayaking, biking) and baking!