Northwestern University Feinberg School of Medicine

Karen Ridge Lab

Publications

Learn more about the work that we do in the Ridge Lab through our recent publications.

 

The cGAS-STING pathway: The role of self-DNA sensing in inflammatory lung disease

Ma R, Ortiz Serrano TP, Davis J, Prigge AD, Ridge KM

FASEB J. 2020 Aug 28. doi: 10.1096/fj.202001607R.

 

Age-dependent differences in T cell responses to influenza A virus

Prigge AD, Ma R, Coates BM, Singer BD, Ridge KM

Am J Respir Cell Mol Biol. 2020 Jul 1. doi: 10.1165/rcmb.2020-0169TR.

 

Influenza-induced activation of recruited alveolar macrophages during the early inflammatory phase drives lung injury and lethality

Koch CM, Anekalla K, Hu JY-S, Ciesielski M, Gadhvi G, Chen S, Turner M, Cheng Y, Coates BM, Abdala-Valencia H, Reyfman PA, Misharin AV, Budinger GRS, Winter DR, Ridge KM

2020, preprint (bioRxiv 2020.06.08.141309).

 

Vimentin is required for tumor progression and metastasis in a mouse model of non-small cell lung cancer

Berr A, dos Santos G, Wiese K, Davis J, Koch C, Anekalla K, Cheng Y, Ridge KM

2020, preprint (bioRxiv 2020.06.04.130963).

 

A beginner's guide to analysis of RNA sequencing data

Koch CM Chiu SF, Akbarpour M, Bharat A, Ridge KM, Bartom ET, Winter DR

Am J Respir Cell Mol Biol. 2018 Aug;59(2):145-157. doi: 10.1165/rcmb.2017-0430TR.

 

Inflammatory monocytes drive influenza A virus-mediated lung injury in juvenile mice

Coates BM, Staricha KL, Koch CM, Cheng Y, Shumaker DK, Budinger GRS, Perlman H, Misharin AV, Ridge KM

J Immunol 2018 Apr 1;200(7):2391-2404. doi: 10.4049/jimmunol.1701543.

 

Inhibition of the NOD-like receptor protein 3 inflammasome is protective in juvenile influenza A virus infection

Coates BM, Staricha KL, Ravindran N, Koch CM, Cheng Y, Davis JM, Shumaker DK, Ridge KM

Front Immunol. 2017 Jul 10;8:782. doi: 10.3389/fimmu.2017.00782.

 

Lung interstitial macrophages: Establishing identity and uncovering heterogeneity

Koch CM, Chiu SF, Misharin AV, Ridge KM

Am J Respir Cell Mol Biol. 2017 Jul;57(1):7-9. doi: 10.1165/rcmb.2017-0150ED.

 

The role of nucleotide-binding oligomerization domain-like receptors in pulmonary infection

Wiese KM, Coates BM, Ridge KM

Am J Respir Cell Mol Biol. 2017 Aug;57(2):151-161. doi: 10.1165/rcmb.2016-0375TR. 

  

Methods for determining the cellular functions of vimentin intermediate filaments

Ridge KM, Shumaker D, Robert A, Hookway C, Gelfand VI, Janmey PA, Lowery J, Guo M, Weitz DA, Kuczmarski E, Goldman RD

Methods Enzymol. 2016;568:389-426. doi: 10.1016/bs.mie.2015.09.036.

 

Influenza a virus infection, innate immunity, and childhood

Coates BM, Staricha KL, Wiese KM, Ridge KM.

JAMA Pediatr. 2015 Oct;169(10):956-63. doi: 10.1001/jamapediatrics.2015.1387.

 

Vimentin regulates activation of the NLRP3 inflammasome

dos Santos G, Rogel MR, Baker MA, Troken JR, Urich D, Morales-Nebreda L, Sennello JA, Kutuzov MA, Sitikov A, Davis JM, Lam AP, Cheresh P, Kamp D, Shumaker DK, Budinger GR, Ridge KM

Nat Commun. 2015 Mar 12;6:6574. doi: 10.1038/ncomms7574.

  

The role of vimentin intermediate filaments in the progression of lung cancer

Kidd ME, Shumaker DK, Ridge KM

Am J Respir Cell Mol Biol. 2014 Jan;50(1):1-6. doi: 10.1165/rcmb.2013-0314TR.