Northwestern University Feinberg School of Medicine

Peter Lab

About Our Lab

The lab of Dr. Marcus E. Peter studies various forms of cell death including apoptosis, which is a fundamental process to regulate homeostasis of all tissues and to eliminate unwanted cells specifically in the immune system. Another interest lies in the study of RNA interference and based on toxic RNAs to development a novel form of cancer treatment. The laboratory is located within the Robert H. Lurie Cancer Center at Northwestern University.


Huntington's disease provides new cancer weapon

Trinucleotide repeat disorders like Huntington's disease show severe neurological pathologies, but are also characterised by reduced cancer susceptibility. A new study from the PeterLab demonstrates that siRNAs based on trinucleotide repeats show specific toxicity against cancer cells, explaining the low cancer incidence in triple repeat diseases.

Interview with Dr. Peter on the show Futureproof on newstalk 106-108fm Ireland

(aired 02-24-2018)
The interview with Dr Peter starts at minute 30:56

Suicide Molecules Kill Any Cancer Cell

Small RNA molecules can trigger a mechanism hidden in every cell, forcing it to commit suicide, according to a new Northwestern Medicine study, the first to identify molecules that trigger such a fail-safe mechanism.

Click here to read the press release.

GW Podcast Interview of Dr. Peter

Peter Lab discusses toxic RNAs to kill cancer cells on The GW Center for Healthcare Innovation & Policy Research podcast. 

Click here to listen to the interview. 

In August 2015, Dr. Peter was selected as an inaugural recipient of the NCI R35 Outstanding Investigator Award (OIA), which provides seven years of research support to investigators with outstanding records of productivity and achievement in cancer research

Postdoctoral Position

A postdoctoral position is available in the laboratory of Dr. Marcus Peter to study the role of toxic RNAs to kill cancer cells as described in eLife 6, e29702, 2017.

Successful candidates should be highly motivated and have a recent Ph.D. degree with strong background in molecular biology and/or cell biology. Experience in working with protein and RNA methods is required. Experience in working with mice would be desired but is not mandatory.

Interested individuals should send a C.V. and names of three references to the address below or by email: 

Marcus Peter
Northwestern University
Feinberg School of Medicine
303 E Superior St, Lurie 6-123
Chicago, Il 60611

Recent Publications

For more publication information see Northwestern Scholars and for more information see Marcus Ernst Peter, PhD, faculty profile.

Marcus Ernst Peter, PhD

Marcus Ernst Peter, PhD

Marcus E. Peter, Ph.D. Tomas D. Spies Professor of Cancer Metabolism, Department of Medicine, Division Hematology/Oncology.
Member and Program Leader "Translational Research in Solid Tumors (TRIST)" Robert H. Lurie Comprehensive Cancer Center.