Lab Members
Meet the lab members! We welcome requests for information about our work and collaboration opportunities. Visit our About Us page for contact information and opportunities to join our team.
Principal Investigator

P. Hande Ozdinler, PhD
Associate Professor
312-503-2774
PhD: LSU/Health Sciences Center
View Ozdinler's Faculty Profile
Dr. Ozdinler received training in the fields of molecular biology, genetics, biotechnology, cell biology, anatomy and neuroscience. She is the recipient of Harvard NeuroDiscovery Center and NUCATS Translational Innovation awards. She was recruited to be the founding director of the 2nd Les Turner ALS Laboratory at Northwestern, which focused on the biology and pathology of upper motor neurons. She is now a faculty member to the Chemistry Life Sciences Processes Institute, Les Turner ALS, Mesulam Center for Cognitive Neurology and Alzheimer's Disease, and Robert H. Lurie Comprehensive Cancer Research Centers.
Research Professor

Mukesh Gautam, Ph.D.
312-503-7132
Dr. Gautam's research is focused on understanding the cellular and molecular mechanisms involved in neuronal vulnerability especially in ALS/FTD. He uses electron microscopy, metabolomics, transcriptomics, extracellular vesicle, and nanoparticle-mediated approaches to understand the basis of selective neurodegeneration. He is especially interested in mitochondria biology in neurodegenerative diseases and improving mitochondria function as a therapeutic strategy to improve neuronal health. Dr. Gautam earned his PhD in reproductive endocrinology from University of Delhi, India. He received training in the Ozdinler lab and now is a Research Assistant Professor. Dr. Gautam is the recipient of the inaugural Ellen McConnell Blakeman ALS Research Fellowship from A Long Swim Foundation, and his research is supported from a grant from Spastic Paraplegia Foundation.
Postdoctoral Fellow

Afshin Babazadeh, Ph.D.
Afshin Babazadeh received his PhD from Macquarie Medical School at Macquarie University in Sydney, Australia, where he investigated the regulation of the ubiquitin-proteasome system (UPS) and the autophagy-lysosomal pathway (ALP) in relation to the aggregation and accumulation of TAR DNA/RNA-binding protein 43 (TDP-43) in cellular and zebrafish models of motor neuron diseases. During his PhD studies, he was awarded the Macquarie Medical School Small Grant Scheme and received the best review paper award. Dr. Babazadeh joined the Ozdinler Lab to pursue postdoctoral studies in motor neuron diseases.

Christopher Quintanilla, Ph.D.
312-503-2776
Christopher Quintanilla completed his doctoral research at the University of Chicago, where he studied the role of Cdx genes in the early development of the zebrafish embryo. He joined the Ozdinler lab in the fall of 2020 and is currently studying how cytoskeletal dysfunction of upper motor neurons (UMNs) contributes to the onset of neurodegenerative diseases.

Emel Ulupinar, M.D. Ph.D.
Professor Emel Ulupinar graduated from Gazi University Faculty of Medicine in 1992. She studied at Cell Biology and Anatomy Department of Louisiana State University Health Sciences Center and received her PhD in 1999. Since then she has been a faculty member at Eskisehir Osmangazi University, Faculty of Medicine, Anatomy Department. She received "Distinguished Young Scientist Award" from the Turkish Academy of Sciences in 2001. She was the Congress Secretary of "First National Neuroscience Meeting" in 2002. She has been working as the head of Interdisciplinary Neuroscience Department, in Health Sciences Institute of Eskisehir Osmangazi University, since 2012.
Lab Manager

Baris Genc, Ph.D.
Dr. Baris Genc has received his PhD at Louisiana State University Department of Cell Biology and Anatomy where he investigated the role of neurotrophic factors in sensory neuron development. During his Postdoctoral training he switched from neurodevelopment to neurodegeneration field. Currently his research is focused on understanding upper motor neuron biology in ALS, and cellular and molecular mechanisms of selective motor neuron vulnerability in ALS. He was the recipient of the NIH Mechanisms of Aging and Dementia T32 training grant investigating molecular mechanisms of selective vulnerability of motor neurons in ALS.
Research Staff

Gulina Ekmen
Gulina Ekmen graduated from Yeditepe University Faculty of Medicine in 2023. She previously conducted research in developmental biology in Germany, then joined the Ozdinler Lab in the winter of 2024. She focuses on drug discovery and neuronal imaging. Gulina hopes to pursue residency in United States.

Zehra Yagmur Erol
Zehra Yagmur Erol graduated from Yeditepe University with a BS in Genetics and Bioengineering, and a MSc in Physiology. She completed her thesis by investigating electrophysiological and behavioral alterations in transgenic mouse models. She previously worked on optical imaging of calcium and voltage sensitive dyes on mouse brain sections, and her current research interests are electrophysiology, optogenetic, calcium imaging and computational neuroscience. Zehra wants to pursue a PhD in Neuroscience.

Jacob Sowizral
Jacob graduated from UIUC in 2024. His research primarily focused on CNF toxins, specifically the modulation of their active site and its effects on cell structure. He now works on various projects in the lab and is excited to learn alongside experienced researchers. Jacob plans to apply to medical school with the aspiration of becoming a neurosurgeon.
Graduate Students

Sarah Yoshimi Tropp
Sarah graduated from the University of Toronto with a BSc in Molecular Biology and a minor in Chemistry. She is currently a PhD student in the Driskill Graduate Program, focused on advancing drug delivery efforts and developing targeted therapeutic strategies. Outside the lab, she plays violin, enjoys cooking, and dabbles in photography/videography.
Undergraduate Students

Taray Noah Sterling
Taray is a first-year student at Northwestern University, currently majoring in neuroscience. He has been in the Ozdinler lab since the fall of 2024 and hopes to pursue a MD with a future specialization in neurology. His interests include disease mechanisms and brain plasticity.
Visiting Professors

Mihailo Radojicic
Mihailo S Radojicic received his M.D. at Belgrade University School of Medicine, Belgrade, Serbia and was a Postdoctoral Fellow at Yale University School of Medicine, New Haven, CT. He is currently a Research Scientist at University of Belgrade, Faculty of Biology, Department of Physiology and Visiting Research Scientist at Northwestern University Feinberg School of Medicine, Department of Neurology.
Alumni
Izaak Aguilar
Now: Research Technologist II at NeuronaTherapeutics
Angela Ahrens
Now: Research Associate at Pathos
Dila Bitlis
student at Northwestern University.
Jonathan Brent
Now: Assistant Prof. at the Department of Neurology, Northwestern University
Ina Dervishi
Now: Neurocrital Care Fellow and Neurologist at the University of Chicago Medical School
Zach Fitzgerald
Now: PhD student at NUIN
Öge Gozütok Moore
Now: Regulatory Affairs Coordinator at Northwestern University
Aksu Gunay
Now: PhD student at UIC
Ben Helmold
Now: MD Candidate at Duke University School of Medicine
Javier Jara
Now: Imaging Director at Nikon Instruments
Omar Kashow
Nabil Khan
Now: Physician at Weiss Memorial Hospital
Nuran Kocak
Now: PhD Student at Stiles-Nicholson Brain Institute.
Amiko Lagrimas
Now: Research Associate at Exicure
Kate Pauss
Now: PhD student at University of Kentucky College of Medicine
Mina Peric
Now: PhD student at the University of Belgrade.
Onur K Polat
Now: Postdoctoral fellow, Rush University, Medical School
Heather Hye Shin
Now: Research Associate, Standford University
Macdonnell Stanford
Now: MD at the Department of Neurology, Brown University
Rosalind Wang
Now: Graduate Student at University of Wisconsin School of Pharmacy
William Weber
Now: Emergency Room Physician, University of Chicago
Edward Xie
Now: Stony Brook University Hospital, Opthalmology
Marina Yasvoina
Now: Lecturer in Neuroscience, King's College London