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Northwestern University Feinberg School of Medicine
Biomaterials for Image-Guided Medicine Lab

Publications

Learn more about the work that we do in the BIGMed Lab through our recent publications.

Featured Publication

  1. Hyunjun Choi, Bongseo Choi, Dong-Hyun Kim Anaerobic Bacterial Metabolism Responsive Microspheres for Bacterial Embolization Cancer Therapy Biomaterials, 2024, October 19.
  2. Min Jun Ko, Sanghee Lee, Yoo Sang Jeon, Dong-Hyun Kim Dynamic fractal ice nano-nucleators for cancer cryotherapy Nano Today, 2024, September 16.
  3. Lee S, Ko MJ, Avritscher R, Lewandowski RJ, Kim DH  Cryo-Nanocatalyst Enhances Therapeutic Efficacy of Cryo-Immunotherapy through Necroptosis and Local Delivery of Programmed Death-Ligand 1 Inhibitors.  ACS Nano  2024, August 22.
  4. Arun Gupta, Ji Yong Park, Hyunjun Choi, Tae Hyeon Choi, Yujin Chung, Dong-Hyun Kim, Yun-Sang Lee Development of Alginate-Based Biodegradable Radioactive Microspheres Labeled with Positron Emitter through Click Chemistry Reaction: Stability and PET Imaging Study ACS Molecular Pharmaceutics, 2024, August 22. 

 

All Recent Publications

  1. Choi H, Choi B, Kim DH  Anaerobic bacterial metabolism responsive microspheres for bacterial embolization cancer therapy.  Biomaterials  2025 Mar;314:122902. doi:10.1016/j.biomaterials.2024.122902
  2. Lee S, Ko MJ, Avritscher R, Lewandowski RJ, Kim DH  Cryo-Nanocatalyst Enhances Therapeutic Efficacy of Cryo-Immunotherapy through Necroptosis and Local Delivery of Programmed Death-Ligand 1 Inhibitors.  ACS Nano  2024 Sep 03;18(35):24269-24282. doi:10.1021/acsnano.4c05809
  3. Choi SJ, Lee S, Choi H, Ko MJ, Kim D, Kim DH  Development of injectable colloidal solution forming an in situ hydrogel for tumor ablation.  Biomater Sci  2024 Aug 20;12(17):4483-4492. doi:10.1039/d4bm00598h
  4. Yu B, Kwak K, Lewandowski RJ, Kim DH  Integration of Ethanol and the Immune Modulator Curcumin for Immunoablation of Hepatocellular Carcinoma.  J Vasc Interv Radiol  2024 Jul;35(7):1033-1042.e11. doi:10.1016/j.jvir.2024.03.014
  5. Lee H, Boor SA, Hilbert ZA, Meisel JD, Park J, Wang Y, McKeown R, Fischer SEJ, Andersen EC, Kim DH  Genetic variants that modify neuroendocrine gene expression and foraging behavior of C. elegans.  Sci Adv  2024 Jun 14;10(24):eadk9481. pii:eadk9481
  6. Ko MJ, Yoo W, Min S, Zhang YS, Joo J, Kang H, Kim DH  Photonic control of image-guided ferroptosis cancer nanomedicine.  Coord Chem Rev  2024 Feb 01;500. pii:215532
  7. Ko MJ, Min S, Hong H, Yoo W, Joo J, Zhang YS, Kang H, Kim DH  Magnetic nanoparticles for ferroptosis cancer therapy with diagnostic imaging.  Bioact Mater  2024 Feb;32:66-97. doi:10.1016/j.bioactmat.2023.09.015
  8. Kim H, Choi B, Mouli SK, Choi H, Harris KR, Kulik LM, Lewandowski RJ, Kim DH  Preclinical Development and Validation of Translational Temperature Sensitive Iodized Oil Emulsion Mediated Transcatheter Arterial Chemo-Immuno-Embolization for the Treatment of Hepatocellular Carcinoma.  Adv Healthc Mater  2023 Oct;12(26):e2300906. pii:2300906
  9. Lee H, Boor SA, Hilbert ZA, Meisel JD, Park J, Wang Y, McKeown R, Fischer SEJ, Andersen EC, Kim DH  Genetic Variants That Modify the Neuroendocrine Regulation of Foraging Behavior in C. elegans.  bioRxiv  2023 Sep 19;. pii:2023.09.09.556976
  10. Choi B, Pe J, Yu B, Kim DH  Syngeneic N1-S1 Orthotopic Hepatocellular Carcinoma in Sprague Dawley Rat for the Development of Interventional Oncology-Based Immunotherapy: Survival Assay and Tumor Immune Microenvironment.  Cancers (Basel)  2023 Jan 31;15(3). pii:913
  11. Kassam Z, Lang R, Bates DDB, Chang KJ, Fraum TJ, Friedman KA, Golia Pernicka JS, Gollub MJ, Harisinghani M, Khatri G  et al.  Correction: SAR user guide to the rectal MR synoptic report (primary staging).  Abdom Radiol (NY)  2023 Jan;48(1):200. doi:10.1007/s00261-022-03656-5
  12. Kassam Z, Lang R, Bates DDB, Chang KJ, Fraum TJ, Friedman KA, Golia Pernicka JS, Gollub MJ, Harisinghani M, Khatri G  et al.  SAR user guide to the rectal MR synoptic report (primary staging).  Abdom Radiol (NY)  2023 Jan;48(1):186-199. doi:10.1007/s00261-022-03578-2
  13. Pe J, Choi B, Choi H, Kwon SW, Kim DH  Preclinical Therapeutic Evaluation of Lenvatinib-Eluting Microspheres for Transcatheter Arterial Chemoembolization of Hepatocellular Carcinoma.  Cardiovasc Intervent Radiol  2022 Dec;45(12):1834-1841. doi:10.1007/s00270-022-03242-8
  14. Kassam Z, Lang R, Arya S, Bates DDB, Chang KJ, Fraum TJ, Friedman KA, Golia Pernicka JS, Gollub MJ, Harisinghani M  et al.  Update to the structured MRI report for primary staging of rectal cancer : Perspective from the SAR Disease Focused Panel on Rectal and Anal Cancer.  Abdom Radiol (NY)  2022 Oct;47(10):3364-3374. doi:10.1007/s00261-022-03612-3
  15. Kim KS, Choi B, Choi H, Ko MJ, Kim DH, Kim DH  Enhanced natural killer cell anti-tumor activity with nanoparticles mediated ferroptosis and potential therapeutic application in prostate cancer.  J Nanobiotechnology  2022 Sep 29;20(1):428. pii:428
  16. Kim DH  Combination of interventional oncology local therapies and immunotherapy for the treatment of hepatocellular carcinoma.  J Liver Cancer  2022 Sep;22(2):93-102. doi:10.17998/jlc.2022.03.28
  17. Choi H, Choi B, Han JH, Shin HE, Park W, Kim DH  Reactive Oxygen Species Responsive Cleavable Hierarchical Metallic Supra-Nanostructure.  Small  2022 Sep;18(38):e2202694. doi:10.1002/smll.202202694
  18. Kwak K, Yu B, Lewandowski RJ, Kim DH  Recent progress in cryoablation cancer therapy and nanoparticles mediated cryoablation.  Theranostics  2022;12(5):2175-2204. doi:10.7150/thno.67530
  19. Choi B, Kim DH  Multifunctional Nanocarriers-Mediated Synergistic Combination of Immune Checkpoint Inhibitor Cancer Immunotherapy and Interventional Oncology Therapy.  Adv Nanobiomed Res  2021 Oct;1(10). pii:2100010
  20. Sim T, Choi B, Kwon SW, Kim KS, Choi H, Ross A, Kim DH  Magneto-Activation and Magnetic Resonance Imaging of Natural Killer Cells Labeled with Magnetic Nanocomplexes for the Treatment of Solid Tumors.  ACS Nano  2021 Aug 24;15(8):12780-12793. doi:10.1021/acsnano.1c01889
  21. Park W, Kim SJ, Cheresh P, Yun J, Lee B, Kamp DW, Kim DH  Magneto mitochondrial dysfunction mediated cancer cell death using intracellular magnetic nano-transducers.  Biomater Sci  2021 Aug 21;9(16):5497-5507. doi:10.1039/d1bm00419k
  22. Kim KS, Kim DH, Kim DH  Recent Advances to Augment NK Cell Cancer Immunotherapy Using Nanoparticles.  Pharmaceutics  2021 Apr 09;13(4). pii:525
  23. Park W, Cho S, Ji J, Lewandowski RJ, Larson AC, Kim DH  Development and Validation of Sorafenib-eluting Microspheres to Enhance Therapeutic Efficacy of Transcatheter Arterial Chemoembolization in a Rat Model of Hepatocellular Carcinoma.  Radiol Imaging Cancer  2021 Jan;3(1):e200006. pii:e200006
  24. Choi H, Choi B, Yu B, Li W, Matsumoto MM, Harris KR, Lewandowski RJ, Larson AC, Mouli SK, Kim DH  On-demand degradable embolic microspheres for immediate restoration of blood flow during image-guided embolization procedures.  Biomaterials  2021 Jan;265:120408. doi:10.1016/j.biomaterials.2020.120408
  25. Yu B, Zhang W, Kwak K, Choi H, Kim DH  Electric Pulse Responsive Magnetic Nanoclusters Loaded with Indoleamine 2,3-Dioxygenase Inhibitor for Synergistic Immuno-Ablation Cancer Therapy.  ACS Appl Mater Interfaces  2020 Dec 09;12(49):54415-54425. doi:10.1021/acsami.0c15679
  26. Choi B, Choi H, Yu B, Kim DH  Synergistic Local Combination of Radiation and Anti-Programmed Death Ligand 1 Immunotherapy Using Radiation-Responsive Splintery Metallic Nanocarriers.  ACS Nano  2020 Oct 27;14(10):13115-13126. doi:10.1021/acsnano.0c04701
  27. Kwak K, Yu B, Mouli SK, Larson AC, Kim DH  Sodium Cholate Bile Acid-Stabilized Ferumoxytol-Doxorubicin-Lipiodol Emulsion for Transcatheter Arterial Chemoembolization of Hepatocellular Carcinoma.  J Vasc Interv Radiol  2020 Oct;31(10):1697-1705.e3. doi:10.1016/j.jvir.2020.01.026
  28. Zhang W, Choi H, Yu B, Kim DH  Synthesis of iron oxide nanocube patched Janus magnetic nanocarriers for cancer therapeutic applications.  Chem Commun (Camb)  2020 Aug 04;56(62):8810-8813. doi:10.1039/d0cc03614e
  29. Yu B, Choi B, Li W, Kim DH  Magnetic field boosted ferroptosis-like cell death and responsive MRI using hybrid vesicles for cancer immunotherapy.  Nat Commun  2020 Jul 20;11(1):3637. pii:3637
  30. Park W, Cho S, Kang D, Han JH, Park JH, Lee B, Lee J, Kim DH  Tumor Microenvironment Targeting Nano-Bio Emulsion for Synergistic Combinational X-Ray PDT with Oncolytic Bacteria Therapy.  Adv Healthc Mater  2020 Jul;9(13):e1901812. doi:10.1002/adhm.201901812
  31. Choi B, Jung H, Yu B, Choi H, Lee J, Kim DH  Sequential MR Image-Guided Local Immune Checkpoint Blockade Cancer Immunotherapy Using Ferumoxytol Capped Ultralarge Pore Mesoporous Silica Carriers after Standard Chemotherapy.  Small  2019 Dec;15(52):e1904378. doi:10.1002/smll.201904378
  32. Cho S, Min NG, Park W, Kim SH, Kim DH  Janus Microcarriers for Magnetic Field-controlled Combination Chemotherapy of Hepatocellular Carcinoma†.  Adv Funct Mater  2019 Jun 27;29(26). pii:1901384