Biomaterials and Multimodal Imaging Guided Therapy
The BIGMed Lab
The Biomaterials for Image-Guided Medicine (BIGMed) Lab develops therapeutic and imaging carriers for cancer treatment. Micro- and nanoparticles, along with their hybrid derivatives, are used as vectors for drug delivery and molecular imaging. We collaborate closely with clinicians, medical scientists, biologists and imaging professionals to translate innovative therapeutic approaches into clinical practice using multifunctional carriers and diagnostic imaging techniques.
Principal Investigator
Dong-Hyun Kim, PhD
Professor, Radiology (Basic and Translational Radiology Research)
Professor, McCormick School of Engineering (Biomedical Engineering)
Latest Lab News
Publication highlighted as the cover article in Molecular Pharmaceutics
One of our latest scientific publication "Development of Alginate-Based Biodegradable Radioactive Microspheres Labeled with Positron Emitter through Click Chemistry Reaction: Stability and PET Imaging Study" has been featured as the cover article in Molecular Pharmaceutics.
This work represents a significant step forward in the development of Biodegradable Radioactive Microspheres for PET Imaging. Read the article
Improving Next-Generation Cancer Treatments
Our recent work "Cryo-Nanocatalyst Enhances Therapeutic Efficacy of Cryo-Immunotherapy through Necroptosis and Local Delivery of Programmed Death-Ligand 1 Inhibitors" published in ACS Nano, has been featured by the Northwestern University Feinberg School of Medicine Northwestern Medicine News Center
Feature in Feinberg Radiology Publication
The BIGMed Lab was featured in The Read, Vol. 8, the official publication of the Department of Radiology at Northwestern University Feinberg School of Medicine.
WBC 2024 Keynote Speaker
Principal Investigator Dong-Hyun Kim, PhD, provided the keynote session on Biomaterials for Image-Guided Therapy for the World Biomaterials Conference 2024 on May 29, 2024.
Advanced Healthcare Materials 2023
Our lab's research paper "Local Embo-Immunotherapy of Hepatocellular Carcinoma" is featured in the frontispiece of Advanced Healthcare Materials.
Nanomedicine News Coverage
A review paper from the BIGMed Lab is highlighted in the Nanomedicine News section of AZO Nano and the cover page of “Advanced Nanobiomed Research” Journal. This article was awarded Top Cited Article in Advanced NanoBioMed 2022-2023.
Nano Micro Small article
The research paper "Degradable gold metallic nanoparticles" is featured in the cover of the September 2022 journal Small.
2022 NCI Conference
Principal Investigator Dong-Hyun Kim, PhD, gives a talk on Microbial-based Cancer Theranostics at the National Cancer Institute conference on May 25, 2022.
Snowflake Nanoparticle Boosts Cancer Therapy
One of our therapeutic breakthroughs received coverage in the Northwestern University Feinberg School of Medicine News Center and Northwestern Medicine Breakthroughs for Physicians.