
Resting state functional connectivity mapsMaps (in yellow and orange) display connectivity between inferior frontal gyrus (IFG) and the rest of the language network within the left brain hemisphere. The left picture depicts the map in a group of healthy individuals. The right picture depicts the map in group of individuals with primary progressive aphasia (PPA). Resting state functional connectivity mapsMaps (in yellow and orange) display connectivity between inferior frontal gyrus (IFG) and the rest of the language network within the left brain hemisphere. The left picture depicts the map in a group of healthy individuals. The right picture depicts the map in group of individuals with primary progressive aphasia (PPA). 
Overview
Based at the
Mesulam Center for Cognitive Neurology and Alzheimer's Disease, our laboratory uses multimodal neuroimaging, especially functional magnetic resonance imaging (fMRI), to study the underlying neural mechanisms of language impairment (aphasia) and impairment in other areas of cognition. Currently the major focus of the lab is primary progressive aphasia (PPA). Our long-term goal is to understand the pathophysiology of PPA and to use that information to develop and evaluate effective treatments for aphasia.