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Northwestern University Feinberg School of Medicine
Abdel Mohsen Lab

Publications

Learn more about the work that we do in the Abdel-Mohsen Laboratory through our recent publications.

  1. Giron LB, Borjabad A, Hadas E, et al., Volsky DJ, Abdel-Mohsen M. Inhibiting glycan degradation prevents HIV-induced inflammaging and cognitive impairment. Med. 2026 Jul 10;7(7):101175. doi: 10.1016/j.medj.2026.101175. Epub 2026 Jun 5. PMID: 42248145; PMCID: PMC13618882.
  2. Singh S, Islam SMS, Liu R, et al., Hultquist JF, Xiao H, Abdel-Mohsen M. HIV-induced sialoglycans on infected CD4+ T cells promote immune evasion from myeloid cell-mediated killing. Nat Commun. 2025 Dec 13;17(1):18. doi: 10.1038/s41467-025-66540-y. PMID: 41390763; PMCID: PMC12764780.
  3. Saini P, Mirji G, Islam SMS, et al., Zhang R, Hultquist JF, Shinde RS, Abdel- Mohsen M. Targeting Interactions Between Siglec-10 and α3β1 Integrin Enhances Macrophage-Mediated Phagocytosis of Pancreatic Cancer. Cancer Res. 2026 Jan 2;86(1):99-115. doi: 10.1158/0008-5472.CAN-25-0977. PMID: 41182080; PMCID: PMC12671567.
  4. Giron LB, Liu Q, Adeniji OS, Yin X, Kannan T, Ding J, Lu DY, Langan S, Zhang J, Abdel-Mohsen M et al. Immunoglobulin G N-glycan markers of accelerated biological aging during chronic HIV infection. Nat Commun. 2024 Apr 10;15(1):3035. doi:10.1038/s41467-024-47279-4.
  5. Nie H, Saini P, Miyamoto T, Liao L, Zielinski RJ, Liu H, Zhou W, Wang C, Murphy B, Abdel-Mohsen M et al. Targeting branched N-glycans and fucosylation sensitizes ovarian tumors to immune checkpoint blockade. Nat Commun. 2024 Apr 2;15(1):2853. doi: 10.1038/s41467-024-47069-y. 
  6. Singh S, Giron LB, Shaikh MW, Shankaran S, Engen PA, Bogin ZR, Bambi SA, Goldman AR, Azevedo JLLC, Abdel-Mohsen M et al. Distinct intestinal microbial signatures linked to accelerated systemic and intestinal biological aging. Microbiome. 2024 Feb 22;12(1):31. doi: 10.1186/s40168-024-01758-4. 
  7. Yuan Z, Giron LB, Hart C, Gyampoh A, Koshy J, Hong KY, Niki T, Premeaux TA, Ndhlovu LC, Abdel-Mohsen M et al. Human galectin-9 promotes the expansion of HIV reservoirs in vivo in humanized mice. AIDS. 2023 Mar 15;37(4):571-577. doi: 10.1097/QAD.0000000000003443. 
  8. Giron LB, Peluso MJ, Ding J, Kenny G, Zilberstein NF, Koshy J, Hong KY, Rasmussen H, Miller GE, Abdel-Mohsen M et al. Markers of fungal translocation are elevated during post-acute sequelae of SARS- CoV-2 and induce NF-κB signaling. JCI Insight. 2022 Aug 8;7(15):e160989. doi: 10.1172/jci.insight.160989. 
  9. Adeniji OS, Kuri-Cervantes L, Yu C, Xu Z, Ho M, Chew GM, Shikuma C, Tomescu George AF, Roan NR, Abdel-Mohsen M et al. Siglec-9 defines and restrains a natural killer subpopulation highly cytotoxic to HIV-infected cells. PLoS Pathog. 2021 Nov 11;17(11):e1010034. doi: 10.1371/journal.ppat.1010034. 
  10. Giron LB, Palmer CS, Liu Q, Yin X, Papasavvas E, Sharaf R, Etemad B, Damra M, Goldman AR, Abdel-Mohsen M et al. Non-invasive plasma glycomic and metabolic biomarkers of post-treatment control of HIV. Nat Commun. 2021 Jun 29;12(1):3922. doi: 10.1038/s41467-021-24077-w. 
  11. Abdel-Mohsen M, Richman D, Siliciano RF, Nussenzweig MC, Howell BJ, Martinez-Picado J, Chomont N, Bar KJ, Yu XG, Lichterfeld M et al. Recommendations for measuring HIV reservoir size in cure-directed clinical trials. Nat Med. 2020 Sep;26(9):1339-1350. doi: 10.1038/s41591-020-1022-1. 
  12. Colomb F, Giron LB, Kuri-Cervantes L, Adeniji OS, Ma T, Dweep H, Battivelli E, Verdin E, Palmer CS, Abdel-Mohsen M et al. Sialyl-LewisX Glycoantigen Is Enriched on Cells with Persistent HIV Transcription during Therapy. Cell Rep. 2020 Aug 4;32(5):107991. doi: 10.1016/j.celrep.2020.107991. 
  13. Giron LB, Tanes CE, Schleimann MH, Engen PA, Mattei LM, Anzurez A, Damra M, Zhang H, Bittinger K, Abdel-Mohsen M et al. Sialylation and fucosylation modulate inflammasome-activating eIF2 Signaling and microbial translocation during HIV infection. Mucosal Immunol. 2020 Sep;13(5):753-766. doi: 10.1038/s41385-020-0279-5. 
  14. Abdel-Mohsen M, Kuri-Cervantes L, Grau-Exposito J, Spivak AM, Nell RA, Tomescu C, Vadrevu SK, Giron LB, Serra-Peinado C, Genescà M et al. CD32 is expressed on cells with transcriptionally active HIV but does not enrich for HIV DNA in resting T cells. Sci Transl Med. 2018 Apr 18;10(437):eaar6759. doi: 10.1126/scitranslmed.aar6759.