Publications

Learn more about the work that we do in the Ridge Lab through these selected publications.

Vimentin is required for tumor progression and metastasis in a mouse model of non-small cell lung cancer. Berr AL, Wiese K, Dos Santos G, Koch CM, Anekalla KR, Kidd M, Davis JM, Cheng Y, Hu Y-S, Ridge KM. Oncogene. 2023 May; https://doi.org/10.1038/s41388-023-02703-9. PMID: 37161053.
Influenza-induced activation of recruited alveolar macrophages during the early inflammatory phase drives lung injury and lethality. Koch CM, Anekalla KR, Hu Y-S, Davis JM, Ciesielski M, Gadhvi G, Chen S-Y, Turner M, Cheng Y, Coates BM, Abdala-Valencia H, Reyfman PA, Misharin AV, Budinger GRS, Winter DR, Ridge KM. 2022, preprint. https://doi.org/10.1101/2020.06.08.141309.
Pivoting to a remote-learning summer student program during the COVID-19 pandemic. Berr AL, Ridge KM, Hu JY-S. ATS Sch. 2021 Dec; 2(4): 521-534. https://doi.org/10.34197/ats-scholar.2021-0047PS. PMID: 35083460.
The cGAS-STING pathway: The role of self-DNA sensing in inflammatory lung disease. Ma R, Ortiz Serrano TP, Davis J, Prigge AD, Ridge KM. FASEB J. 2020 Oct; 34(10): 13156-13170. https://doi.org/10.1096/fj.202001607R. PMID: 32860267.
Age-dependent differences in T-cell responses to influenza A virus. Prigge AD, Ma R, Coates BM, Singer BD, Ridge KM. Am J Respir Cell Mol Biol. 2020 Oct; 63(4): 415-423. https://doi.org/10.1165/rcmb.2020-0169TR. PMID: 32609537.
Inflammatory monocytes drive influenza A virus-mediated lung injury in juvenile mice. Coates BM, Staricha KL, Koch CM, Cheng Y, Shumaker DK, Budinger GRS, Perlman H, Misharin AV, Ridge KM. J Immunol. 2018 Apr; 200(7): 2391-2404. https://doi.org/10.4049/jimmunol.1701543. PMID: 29445006.
Inhibition of the NOD-like receptor protein 3 inflammasome is protective in juvenile influenza A virus infection. Coates BM, Staricha KL, Ravindran N, Koch CM, Cheng Y, Davis JM, Shumaker DK, Ridge KM. Front Immunol. 2017; 8: 782. https://doi.org/10.3389/fimmu.2017.00782. PMID: 28740490.
Lung interstitial macrophages: Establishing identity and uncovering heterogeneity. Koch CM, Chiu SF, Misharin AV, Ridge KM. Am J Respir Cell Mol Biol. 2017 Jul; 57(1): 7-9. https://doi.org/10.1165/rcmb.2017-0150ED. PMID: 28665216.
The role of nucleotide-binding oligomerization domain-like receptors in pulmonary infection. Wiese KM, Coates BM, Ridge KM. Am J Respir Cell Mol Biol. 2017 Aug; 57(2): 151-161. https://doi.org/10.1165/rcmb.2016-0375TR. PMID: 28157451.
Influenza A virus infection, innate immunity, and childhood. Coates BM, Staricha KL, Wiese KM, Ridge KM. JAMA Pediatr. 2015 Oct; 169(10): 956-963. https://doi.org/10.1001/jamapediatrics.2015.1387. PMID: 26237589.
Vimentin regulates activation of the NLRP3 inflammasome. dos Santos G, Rogel MR, Baker MA, Troken JR, Urich D, Morales-Nebreda L, Sennello JA, Kutuzov MA, Sitikov A, Davis JM, Lam AP, Cheresh P, Kamp D, Shumaker DK, Budinger GRS, Ridge KM. Nat Commun. 2015 Mar; 6: 6574. https://doi.org/10.1038/ncomms7574. PMID: 25762200.