Northwestern University Feinberg School of Medicine

Karen Ridge Lab

Publications

Learn more about the work that we do in the Ridge Lab through our recent publications.

 

A beginner's guide to analysis of RNA-seq data

Koch CM Chiu SF, Akbarpour M, Bharat A, Ridge KM, Bartom ET, Winter DR

Am J Respir Cell Mol Biol. 2018 Apr 6. doi: 10.1165/rcmb.2017-0430TR. [Epub ahead of print]

 

Inflammatory monocytes drive influenza A virus-mediated lung injury in juvenile mice

Coates BM, Staricha KL, Koch CM, Cheng Y, Shumaker DK, Budinger GRS, Perlman H, Misharin AV, Ridge KM

J Immunol 2018 Apr 1;200(7):2391-2404. doi: 10.4049/jimmunol.1701543.

 

Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span

Misharin AV, Morales-Nebreda L, Reyfman PA, Cuda CM, Walter JM, McQuattie-Pimentel AC, Chen CI, Anekalla KR, Joshi N, Williams KJN, Abdala-Valencia H, Yacoub TJ, Chi M, Chiu S, Gonzalez-Gonzalez FJ, Gates K, Lam AP, Nicholson TT, Homan PJ, Soberanes S, Dominguez S, Morgan VK, Saber R, Shaffer A, Hinchcliff M, Marshall SA, Bharat A, Berdnikovs S, Bhorade SM, Bartom ET, Morimoto RI, Balch WE, Sznajder JI, Chandel NS, Mutlu GM, Jain M, Gottardi CJ, Singer BD, Ridge KM, Bagheri N, Shilatifard A, Budinger GRS, Perlman H

J Exp Med. 2017 Aug 7;214(8):2387-2404. doi: 10.1084/jem.20162152.

 

The role of nucleotide-binding oligomerization domain-like receptors in pulmonary infection

Wiese KM, Coates BM, Ridge KM

Am J Respir Cell Mol Biol. 2017 Aug;57(2):151-161. doi: 10.1165/rcmb.2016-0375TR. 

 

Inhibition of the NOD-like receptor protein 3 inflammasome is protective in juvenile influenza A virus infection

Coates BM, Staricha KL, Ravindran N, Koch CM, Cheng Y, Davis JM, Shumaker DK, Ridge KM

Front Immunol. 2017 Jul 10;8:782. doi: 10.3389/fimmu.2017.00782.

 

Lung interstitial macrophages: Establishing identity and uncovering heterogeneity

Koch CM, Chiu SF, Misharin AV, Ridge KM

Am J Respir Cell Mol Biol. 2017 Jul;57(1):7-9. doi: 10.1165/rcmb.2017-0150ED.

  

Methods for determining the cellular functions of vimentin intermediate filaments

Ridge KM, Shumaker D, Robert A, Hookway C, Gelfand VI, Janmey PA, Lowery J, Guo M, Weitz DA, Kuczmarski E, Goldman RD

Methods Enzymol. 2016;568:389-426. doi: 10.1016/bs.mie.2015.09.036.

 

Influenza a virus infection, innate immunity, and childhood

Coates BM, Staricha KL, Wiese KM, Ridge KM.

JAMA Pediatr. 2015 Oct;169(10):956-63. doi: 10.1001/jamapediatrics.2015.1387.

 

Vimentin regulates activation of the NLRP3 inflammasome

dos Santos G, Rogel MR, Baker MA, Troken JR, Urich D, Morales-Nebreda L, Sennello JA, Kutuzov MA, Sitikov A, Davis JM, Lam AP, Cheresh P, Kamp D, Shumaker DK, Budinger GR, Ridge KM

Nat Commun. 2015 Mar 12;6:6574. doi: 10.1038/ncomms7574.

  

The role of vimentin intermediate filaments in the progression of lung cancer

Kidd ME, Shumaker DK, Ridge KM

Am J Respir Cell Mol Biol. 2014 Jan;50(1):1-6. doi: 10.1165/rcmb.2013-0314TR.