Vimentin in Lung AdenocarcinomaTumor cell from a mouse model of adenocarcinoma stained for vimentin (green) and keratin (red)Vimentin in Lung AdenocarcinomaTumor cell from a mouse model of adenocarcinoma stained for vimentin (green) and keratin (red)
Vimentin in Endothelial CellsEndothelial cells stained for vimentin (green) and VE-cadherin (red)Vimentin in Endothelial CellsEndothelial cells stained for vimentin (green) and VE-cadherin (red)
Vimentin in Inflammasome AssemblyMouse BMDM treated with LPS + MSU and stained for vimentin (red) and active caspase-1 (green)Vimentin in Inflammasome AssemblyMouse BMDM treated with LPS + MSU and stained for vimentin (red) and active caspase-1 (green)
About Our Lab
We investigate the type 3 intermediate filament protein vimentin and its role in pulmonary health and disease. We focus on the involvement of vimentin in innate immunity, especially Nod-like receptor signaling, in the lungs of both juveniles and adults. We also explore how vimentin functions in the resolution of acute lung injury and the development of pulmonary fibrosis, as well as its role in non–small cell lung cancer.
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Collaborators
G.R. Scott Budinger, MD
Chief, Division of Medicine-Pulmonary
Professor in Medicine-Pulmonary and Cell and Molecular Biology
Vladimir I. Gelfand, PhD
Professor in Cell and Molecular Biology
Robert Goldman, PhD
Chair, Department of Cell and Molecular Biology
Professor in Cell and Molecular Biology and Medicine-Pulmonary
Jing Liu, PhD
Assistant Professor in Medicine-Pulmonary
Alexander Misharin, MD, PhD
Research Assistant Professor in Medicine-Pulmonary
Jacob I. Sznajder, MD
Professor in Medicine-Pulmonary and Cell and Molecular Biology
