List of Publications

Learn more about the work that we do in the Wu Laboratory through our recent publications below.

Jang H, Li Y, Fung AA, Bagheri P, Hoang K, Skowronska-Krawczyk D, Chen X, Wu JY, Bintu B, Shi L. (2023) Super-resolution SRS microscopy with A-PoD. Nature Methods (Accepted)

Yuasa-Kawada J*, Kinoshita-Kawada M, Tsuboi Y, Wu JY* (2023) Neuronal guidance genes in health and diseases (in press)

Ma J, Wu JY*, Zhu L*.(2022) Detection of orthologous exons and isoforms using EGIO. Bioinformatics. 2022 Aug 10:btac548 PMID: 35946527 [PubMed]

Li Y, Bagheri P, Chang P, Zeng A, Hao J, Fung A, Wu JY, Shi L. (2022) Direct Imaging of Lipid Metabolic Changes in Drosophila Ovary during Aging using DO-SRS Microscopy. Frontiers in Aging 2:819903 PMID: 35822015 [PubMed]

Wu JY (2021) Tongue as a first-line immune organ? Protein Cell. 12(3):162-164 PMC7796681 [PubMed]

Wang F, Chen X, Cheng H, Song L, Liu J, Caplan S, Zhu L*, Wu JY* (2021) MICAL2PV suppresses the formation of tunneling nanotubes and modulates mitochondrial trafficking. EMBO Reports. 22(7):e52006 (*co-corresponding author) [PubMed]

McGee WA, Pimentel H, Pachter L, Wu JY* (2021) Compositional Data Analysis is necessary for simulating and analyzing RNA-Seq data. bioRxiv 564955; doi: https://doi.org/10.1101/564955 [bioRxiv]

Bhosle VK, Mukherjee T, Huang YW, Patel S, Pang BWF, Liu GY, Glogauer M, Wu JY, Grinstein S, Robinson LA (2020) SLIT2/ROBO1-signaling inhibits macropinocytosis by opposing cortical cytoskeletal remodeling. Nature Communications 11(1):4112 PMCID: PMC7431850 [PubMed]

Kinoshita-Kawada M, Hasegawa H, Hongu T, Yanagi S, Kanaho Y, Masai I, M Takayasu, Chen X, Rao Y, Yuasa-Kawada J, Wu JY* (2019) A critical role of Arf6 in the response of commissural axons to Slit. Development 146(3). pii: dev172106. doi: 10.1242/dev.172106. [PubMed]

Wang P, Deng J, Dong J, Liu J, Bigio EH, Mesulam M, Wang T, Sun L, Wang L, Lee A YL, McGee WA, Chen X, Fushimi K, Zhu L*, Wu JY* (2019) TDP-43 induces mitochondrial damage and activates UPRmt. PlosGenetics 15(5):e1007947 [PubMed]

Kinoshita-Kawada M, Hasegawa H, Hongu T, Yanagi S, Kanaho Y, Masai I, Mishima T, Chen X, Tsuboi Y, Rao Y, Yuasa-Kawada J*, Wu JY* (2019) Explant Culture of the Embryonic Mouse Spinal Cord and Gene Transfer by ex vivo 2 Electroporation. BioProtocol (9(18): e3373. [PubMed]

Deng J, Wang P, Chen X, Cheng H, Liu J, Fushimi K, Zhu L, Wu JY*. (2018) FUS interacts with ATP synthase beta subunit and induces mitochondrial unfolded protein response in cellular and animal models. Proc Natl Acad Sci U S A. 115(41):E9678-E9686. doi: 10.1073/pnas.1806655115. [Pubmed, PDF]

Chen Y, Deng J, Wang P, Yang M, Chen X, Zhu L, Liu J, Lu B, Shen Y, Fushimi K*, Xu Q*, Wu JY*. (2016) PINK1 and Parkin are genetic modifiers for FUS-induced neurodegeneration. Hum. Mol. Gen. 2016 Oct 29. doi: 10.1093/hmg/ddw310. [Epub ahead of print] [*co-corresponding author] [Pubmed, PDF]

Chen M, Li Y*, Yang M, Chen X, Chen Y, Yang F, Lu S, Yao S, Zhou T, Liu J, Zhu L, Du S, Wu JY* (2016) A new method for quantifying mitochondrial axonal transport. Protein Cell. 7(11):804-819 [*co-corresponding author] [Pubmed, PDF]

Yi F, Kong R, Ren J, Zhu L, Lou J, Wu JY*, Feng W*. (2016) Noncanonical Myo9b-RhoGAP Accelerates RhoA GTP Hydrolysis by a Dual-Arginine-Finger Mechanism. J Mol Biol. 428(15):3043-57 [*co-corresponding author] [Pubmed]

Zhang Y, Chen M, Qiu Z, Hu K, McGee W, Chen X, Liu J, Zhu L, Wu JY*. (2016) MiR-130a regulates neurite outgrowth and dendritic spine density by targeting MeCP2. Protein Cell. 7(7):489-500 [Pubmed, PDF]

Xu Y, Sun Y, Ye H, Zhu L, Liu J, Wu X, Wang L, He T, Shen Y, Wu JY*, Xu Q*. (2015) Increased dysbindin-1B isoform expression in schizophrenia and its propensity in aggresome formation. Cell Discov. 1:15032 [*co-corresponding author] [Pubmed, PDF]

Kong R, Yi F, Wen P, Liu J, Chen X, Ren J, Li X, Shang Y, Nie Y, Wu K, Fan D, Zhu L, Feng W, Wu JY*. (2015) Myo9b is a key player in SLIT/ROBO-mediated lung tumor suppression. J Clin Invest. 125(12):4407-20 [Pubmed, PDF]

Deng J, Yang M, Chen Y, Chen X, Liu J, Sun S, Cheng H, Li Y, Bigio EH, Mesulam M, Xu Q, Du S, Fushimi K, Zhu L, Wu JY*. (2015) FUS interacts with HSP60 to promote mitochondrial damage. PLoS Genet. 11(9):e1005357 [Pubmed, PDF]

Huang Z*, Wen P, Kong R, Cheng H, Zhang B, Quan C, Bian Z, Chen M, Zhang Z, Chen X, Du X, Liu J, Zhu L, Fushimi K, Hua D, Wu JY*. (2015) USP33 mediates Slit-Robo signaling in inhibiting colorectal cancer cell migration. Int J Cancer. 136(8):1792-802 [*co-corresponding author] [Pubmed, PDF]

Tu T, Zhang C, Yan H, Luo Y, Kong R, Wen P, Ye Z, Chen J, Feng J, Liu F, Wu JY*, Yan X*. (2015) CD146 acts as a novel receptor for netrin-1 in promoting angiogenesis and vascular development. Cell Res. 25(3):275-87 [*co-corresponding author] [Pubmed, PDF]

If you are interested in a complete list of our publications, please browse the accordions below.

2014

Wen P, Kong R, Liu J, Zhu L, Chen X, Li X, Nie Y, Wu K, Wu JY*. (2014) USP33, a new player in lung cancer, mediates Slit-Robo signaling. Protein Cell. 5(9):704-13 [Pubmed, PDF]

Zhu L, Xu M, Yang M, Yang Y, Li Y, Deng J, Ruan L, Liu J, Du S, Liu X, Feng W, Fushimi K, Bigio EH, Mesulam M, Wang C, Wu JY*. (2014) An ALS-mutant TDP-43 neurotoxic peptide adopts an anti-parallel β-structure and induces TDP-43 redistribution. Hum Mol Genet. 23(25):6863-77 [Pubmed, PDF]

Göhrig A, Detjen KM, Hilfenhaus G, Körner J, Arsenic R, Welzel M, Schmuck R, Bahra M, Wu JY, Wiedenmann B, Fischer C. (2014) The Axon Guidance Factor Slit2 inhibits Pancreatic Cancer Metastasis and Cell Movement along Neurites. Cancer Res. 74(5):1529-40 [Pubmed, PDF]

Li Y, Yang M, Huang Z, Chen X, Maloney M, Zhu L, Liu J, Yang Y, Du S, Jiang X, Wu JY. (2014) AxonQuant: a microfluidic chamber culture-coupled algorithm that allows high-throughput quantification of axonal damage. Neurosignals. 22(1):14-29 [Pubmed, PDF] AxonQuant1.0 download

2013

RNA and Cancer. Wu JY (ed.) ISBN 978-3-642-316586; Library of Congress Control Number 2012946188 (Springer, 2013) [Website, book summary]

Post-Transcriptional Gene Regulation-RNA Processing In Eukaryotes. Wu JY (ed.) ISBN 978-3527322022 (Wiley-Blackwell, 2013) [Website, book cover]

Bigio EH, Wu JY, Deng HX, Bit-Ivan EN, Mao Q, Ganti R, Peterson M, Siddique N, Geula C, Siddique T, Mesulam M. (2013) Inclusions in frontotemporal lobar degeneration with TDP-43 proteinopathy(FTLD-TDP) and amyotrophic lateral sclerosis (ALS), but not FTLD with FUS proteinopathy (FTLD-FUS), have properties of amyloid. Acta Neuropathol. 125(3):463-5 [Pubmed, PDF]

Xu M, Zhu L, Liu J, Yang Y, Wu JY, Wang C. (2013) Characterization of β-domains in C-terminal fragments of TDP-43 by scanning tunneling microscopy. J Struct Biol. 181(1):11-6 [Pubmed, PDF]

Chen Q, Sun X, Zhou XH, Liu JH, Wu J, Zhang Y, Wang JH. (2013) N-terminal horseshoe conformation of DCC is functionally required for axon guidance and might be shared by other neural receptors. J Cell Sci. 126:186-95 [Pubmed, PDF]

Zhu K, Chen XP, Liu JH, Ye Hh, Zhu L*, Wu JY*. (2013) AMPK interacts with DSCAM and plays an important role in Netrin-1 induced neurite outgrowth. ProteinCell. 4(2):155–161 [*co-corresponding author] [Pubmed, PDF]

2011

Chen Y, Yang M, Deng J, Chen X, Ye Y, Zhu L, Liu J, Ye H, Shen Y, Li Y, Rao EJ, Fushimi K, Zhou X, Bigio EH, Mesulam M, Xu Q*, Wu JY*. (2011) Expression of human FUS protein in Drosophila leads to progressive neurodegeneration. Protein Cell 2(6):477–486 [*co-corresponding author] [Pubmed, PDF]

Ray P, Kar A, Fushimi K, Havlioglu N, Chen X, Wu JY. (2011) PSF Suppresses Tau Exon 10 Inclusion by Interacting with a Stem-Loop Structure Downstream of Exon 10. J Mol Neurosci. 45(3):453-66 [Pubmed, PDF]

Xu Y, Ye H*, Shen Y, Xu Q*, Zhu L, Liu J, Wu JY*. (2011) Dscam mutation leads to hydrocephalus and decreased motor function. Protein Cell. 2(8):647-55 [*co-corresponding author] [Pubmed, PDF]

Yu B, Fey P, Kestin-Pilcher KE, Fedorov A, Prakash A, Chisholm RL, Wu JY*. (2011) Spliceosomal genes in the D. discoideum genome: a comparison with those in H. sapiens, D. melanogaster, A. thaliana and S. cerevisiae. Protein Cell. 2(5):395-409 [Pubmed, PDF]

Guo W, Chen Y, Zhou X, Kar A, Ray P, Chen X, Rao EJ, Yang M, Ye H, Zhu L, Liu J, Xu M, Yang Y, Wang C, Zhang D, Bigio EH, Mesulam M, Shen Y, Xu Q*, Fushimi K, Wu JY*. (2011) An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity. Nat Struct Mol Biol. 18(7):822-30 [*co-corresponding author] [Pubmed, PDF]

Kar A, Fushimi K, Zhou X, Ray P, Shi C, Chen X, Liu Z, Chen S, Wu JY*. (2011) RNA Helicase p68 (DDX5) regulates tau exon 10 splicing by modulating a stem-loop structure at the 5' splice site. Mol Cell Biol. 31(9):1812-21 [Pubmed, PDF]

Fushimi K, Long C, Jayaram N, Chen X, Li L, Wu JY*. (2011) Expression of human FUS/TLS in yeast leads to protein aggregation and cytotoxicity, recapitulating key features of FUS proteinopathy. Protein Cell. 2(2):141-9 [Pubmed, PDF]

Dunaway CM, Hwang Y, Lindsley CW, Cook RS, Wu JY, Boothby M, Chen J, Brantley-Sieders DM. (2011) Cooperative signaling between Slit2 and Ephrin-A1 regulates a balance between angiogenesis and angiostasis. Mol Cell Biol. 31(3):404-16 [Pubmed, PDF]

Brantley-Sieders DM, Dunaway CM, Rao M, Short S, Hwang Y, Gao Y, Li D, Jiang A, Shyr Y, Wu JY, Chen J. (2011) Angiocrine Factors Modulate Tumor Proliferation and Motility through EphA2 Repression of Slit2 Tumor Suppressor Function in Endothelium. Cancer Res. 71(3):976-987 [Pubmed, PDF]

2010

Gao X, Joselin AP, Wang L, Kar A, Ray P, Bateman A, Goate AM, Wu JY*. (2010) Progranulin promotes neurite outgrowth and neuronal differentiation by regulating GSK-3β. Protein Cell. 1(6):552-62 [Pubmed, PDF]

Guo W, Li JT, Pan X, Wei L*, Wu JY*. (2010) Candidate Mycobacterium tuberculosis genes targeted by human microRNAs. Protein Cell. 1(5):419-21 [*co-corresponding author] [Pubmed, PDF]

Kaneko N, Marín O, Koike M, Hirota Y, Uchiyama Y, Wu JY, Lu Q, Tessier-Lavigne M, Alvarez-Buylla A, Okano H, Rubenstein JL, Sawamoto K. (2010) New neurons clear the path of astrocyticprocesses for their rapid migration in the adult brain. Neuron. 67(2):213-23 [Pubmed, PDF]

Yu J, Cao Q, Yu J, Wu L, Dallol A, Li J, Chen G, Grasso C, Cao X, Lonigro RJ, Varambally S, Mehra R, Palanisamy N, Wu JY, Latif F, Chinnaiyan AM. (2010) The neuronal repellent SLIT2 is a target for repression by EZH2 in prostate cancer. Oncogene. 29(39):5370-80 [Pubmed, PDF]

Ray P, Luo XY, Rao EJ, Basha A, Woodruff EA, Wu JY*. (2010) The splicing factor Prp31 is essential for photoreceptor development in Drosophila. Protein Cell. 1(3):267-274 [Pubmed, PDF]

Li Y*, Ray P, Rao EJ, Shi C, Guo W, Chen X, Woodruff EA, Fushimi K, Wu JY*. (2010) Drosophila model for TDP-43 proteinopathy. Proc Natl Acad Sci USA. 107(7):3169-74 [*co-corresponding author] [Pubmed, PDF]

Barmada SJ, Skibinski G, Korb E, Rao EJ, Wu JY*, Finkbeiner S*. (2010) Cytoplasmic mislocalization of TDP-43 is toxic to neurons and enhanced by a mutation associated with familial amyotrophic lateral sclerosis. J Neurosci. 20(2):639:49 [*co-corresponding author] [Pubmed, PDF]

2009

Yuasa-Kawada J, Kinoshita-Kawada M, Rao Y, Wu JY. (2009b) Deubiquitinating enzyme USP33/VDU1 is required for Slit signaling in inhibiting breast cancer cell migration. Proc. Natl. Acad. Sci. USA. 106(34):14530-5 [Pubmed, PDF]

Yuasa-Kawada J, Kinoshita-Kawada M, Wu G, Rao Y, Wu JY. (2009a) Midline crossing and Slit responsiveness of commissural axons require USP33. Nat Neurosci. 12(9):1087-9 [Pubmed, PDF]

Qiu R, Liu K, Liu Y, Mo W, Flynt AS, Patton JG, Kar A, Wu JY, He R. (2009) The role of miR-124a in early development of the Xenopus eye. Mech Dev. 126(10):804-16 [Pubmed, PDF]

Qiu R, Liu Y, Wu JY, Liu K, Mo W, He R. (2009) Misexpression of miR-196a induces eye anomaly in Xenous laevis. Brain Research Bulletin 76:26-31 [Pubmed, PDF]

Stanwood GD, Leitch DB, Savchenko V, Wu J, Fitsanakis VA, Anderson DJ, Stankowski JN, Aschner M, McLaughlin B. (2009) Manganese exposure is cytotoxic and alters dopaminergic and GABAergicneurons within the basal ganglia. J Neurochem. 110(1):378-89 [Pubmed,Website]

Yiin JJ, Hu B, Jarzynka MJ, Feng H, Liu KW, Wu JY, Ma HI, Cheng SY. (2009) Slit2 inhibits glioma cell invasion in the brain by suppression of Cdc42 activity. Neuro Oncol. 11(6):779-89 [Pubmed, PDF]

Liu G, Li W, Wang L, Kar A, Guan KL, Rao Y, Wu JY. (2009) DSCAM functions as a netrin receptor in commissural axon pathfinding. Proc Natl Acad Sci USA. 106(8):2951-6 [Pubmed, PDF]

2008

Fushimi K, Ray P, Kar A, Wang L, Sutherland LC, Wu JY. (2008) Up-regulation of the proapoptotic caspase 2 splicing isoform by a candidate tumor suppressor, RBM5. Proc. Natl. Acad. Sci. USA. 105: 15708-15713. [Pubmed, PDF]

Wu JY, Potashkin JA. (2009) Alternative Splicing in the Nervous System. The New Encyclopedia of Neuroscience, Edited by Squire L. (Elsevier) [ScienceDirect, PDF]

Li X, Gao X, Liu G, Xiong W, Wu J*, Rao Y*. (2008) Netrin signal transduction and the guanine nucleotide exchange factor DOCK180 in attractive signaling. Nat Neurosci. 11:28-35 [*co-corresponding author] [Pubmed, PDF]

Yang G, Huang SC, Wu JY, Benz EJ Jr. (2008) Regulated Fox-2 isoform expression mediates protein 4.1R splicing during erythroid differentiation. Blood. 111(1):392-401 [Pubmed, PDF]

2007

Altay T, McLaughlin B, Wu JY, Park TS, Gidday JM. (2007). Slit modulates cerebrovascular inflammation and mediates neuroprotection against global cerebral ischemia. Exp Neurol. 207(2):186-94 [Pubmed, PDF]

Mordes D, Yuan L, Xu LL, Kawada M, Molday RS, Wu JY*. (2007). Identification of photoreceptor genes affected by PRPF31 mutations associated with autosomal dominant retinitis pigmentosa. Neurobiol Dis. 26(2):291-300 [Pubmed, PDF]

Liu G, Li W, Gao X, Li X, Jorgensen C, Park HT, Shin NY, Yu J, He ML, Hanks SK, Wu JY, Guan KL, Rao Y. (2007) p130CAS Is Required for Netrin Signaling and Commissural Axon Guidance. J Neurosci. 27(4):957-68 [Pubmed, PDF]

2006

Mordes D, Luo X, Kar A, Kuo D, Xu L, Fushimi K, Yu G , Sternberg P, and Wu JY*. (2006) Pre-mRNA Splicing and Retinitis Pigmentosa. Mol Vis. 12:1259-71 [Pubmed, PDF]

Wu JY*, Kar A, Kuo D, Yu B & Havlioglu N. (2006) SRp54 (SFRS11), a regulator for tau exon 10 alternative splicing identified by an expression cloning strategy. Mol Cell Biol. 26:6739-6747 [* corresponding author] [Pubmed, PDF]

Li X, Chen Y, Liu Y, Gao J, Gao F, Bartlam M, Wu JY*, Rao ZH. (2006). Structural basis of Robo proline-rich motif recognition by the srGAP1 SH3 domain in the slit-robo signaling pathway. J Biol Chem. 281(38):28430-7 [* co-corresponding author] [Pubmed, PDF]

Donahue CP, Muratore C, Wu JY, Kosik KS, Wolfe MS. (2006) Stabilization of the tau exon 10 stem loop alters pre-mRNA splicing. J Biol Chem. 281(33):23302-6 [Pubmed, PDF]

Kar A, Havlioglu N, Tarn WY, Wu JY*. (2006) RBM4 interacts with an intronic element and stimulates tau exon 10 inclusion. J Biol Chem. 281(34):24479-88 [Pubmed, PDF]

Werbowetski-Ogilvie T, Sadr MS, Jabado N, Angers-Loustau A, Agar NYR, Wu J, Bjerkvig R, Antel JA, Faury D, Rao Y, Del Maestro RF. (2006) Inhibition of medulloblastoma cell invasion by Slit. Oncogene. 25(37):5103-12 [Pubmed, PDF]

2005

Kar A, Kuo D, He R, Zhou J, Wu JY*. (2005) Tau Alternative Splicing and Frontotemporal Dementia. Alzheimer Dis Assoc Disord. Oct-Dec;19 Suppl 1:S29-36 [Pubmed, PDF]

Yang G, Huang SC, Wu JY, Benz EJ Jr. (2005) An Erythroid Differentiation-specific Splicing Switch in Protein 4.1R Mediated by the Interaction of SF2/ASF with an Exonic Splicing Enhancer. Blood. 105(5):2146-53 [Pubmed, PDF]

Yuan L, Kawada M, Havlioglu N, Tang H, and Wu JY*. (2005) Mutations in PRPF31 inhibit pre-mRNA splicing of rhodopsin gene and cause apoptosis of retinal cells. J Neurosci. 25(3):748-57 [Pubmed, PDF]

2004

Liu G, Beggs H, Jürgensen C, Park H-T, Tang H, Gorski J, Jones KR, Reichardt LF, Wu JY, Rao Y. (2004) Netrin Requires Focal Adhesion Kinase and Src Family Kinases for Axon Outgrowth and Attraction. Nat Neurosci. 7:1222-1232 [Pubmed, PDF]

Kanellis J, Garcia G, Li P, Para G, Wilson CB, Rao Y, Han S, Smith CW, Johnson RJ, Wu JY, Feng L. (2004) Modulation of inflammation by Slit protein in vivo in experimental crescenticglomerulonephritis. Am J Path. 165(1):341-52 [Pubmed, PDF]

Wu JY*, Yuan L, Havlioglu N. (2004). Alternatively spliced genes. In Encyclopedia of Molecular Cell Biology and Molecular Medicine. Vol1. pp 125-177. Edited by Meyers R.A. (2nd edition) (Wiley-VCH). [GoogleBooks, PDF]

Ward ME, Wu JY*, Rao Y*. (2004) Visualization of spatially and temporally regulated N-WASP activity during cytoskeletal reorganization in living cells. Proc Natl Acad Sci USA. 101:970-974 [* co-corresponding author] [Pubmed, PDF]

2003

Guan H, Zu G, Xie Y, Tang H, Johnson M, Xu X, Kevil C, Xiong W-C, Elmets C, Rao Y, Wu JY, Xu H. (2003) Neuronal repellent Slit2 inhibits dendritic cell migration and the development of immune responses. J Immunol. 171:6519-6526 [Pubmed, PDF]

Ward ME, McCann CM, DeWulf M, Wu JY*, Rao Y*. (2003) Distinguishing Between Directional Guidance and Motility Regulation in Neuronal Migration. J Neurosci. 23(12):5170-7 [* co-corresponding author] [Pubmed, PDF]

Park KW, Morrison CM, Sorensen LK, Jones CA, Rao Y, Chien CB, Wu JY, Urness LD, Li DY. (2003) Robo4 is a vascular-specific receptor that inhibits endothelial migration. Dev Biol. 261(1):251-67 [Pubmed, PDF]

Sobrido M-J, Miller BL, Havlioglu N, Zhukareva V, Jiang Z, Nasreddine ZS, Lee VMY, Chow T, Wilhelmsen KC, Cummings JL, Wu JY, Geschwind DH. (2003) Novel Tau Polymorphisms, Tau Haplotypes and Splicing in Familial and Sporadic Frontotemporal Dementia. Arch Neurol. 60(5):698-702 [Pubmed, PDF]

Yuan WL, Rao Y, Babiuk RP, Greer J, Wu JY, and Ornitz DM. (2003) A genetic model for a central (septum transversum) congenital diaphragmatic hernia in mice lacking Slit3. Proc. Natl. Acad. Sci. USA. 100(9):5217-22 [Pubmed, PDF]

Anselmo MA, Dalvin S, Prodhan P, Komatsuzaki K, Aidlen JT, Schnitzer JJ, Wu JY, Kinane TB. (2003) Slit and robo: expression patterns in lung development. Gene Exp. 3(1):13-9 [Pubmed, PDF]

Jiang Z, Tang H, Havlioglu, N. Zhang, X, Stamm S, Yan R, Wu JY*. (2003) Mutations in tau exon10 associated with FTDP-17 alter the activity of an exonic splicing enhancer to interact with Tra2beta. J Biol Chem. 278(21):18997-9007 [Pubmed, PDF]

2002

Sang Q, Wu J, Rao Y, Hsueh, Y-P, Tan SS. (2002) Slit Promotes Branching and Elongation of Neurites of Interneurons But Not Projection Neurons from the Developing Telencephalon. Mol Cell Neurosci. 21(2):250-65 [Pubmed, PDF]

Havlioglu N, Tang H, Wu JY*. (2002) Slit, Potential Endogenous Modulators of Inflammation. J Neurovirol. 8(6):486-95 [Pubmed, PDF]

Rao Y, Wong K, Ward M, Jurgensen C, Wu JY. (2002) Neuronal Migration and molecular conservation with leukocyte chemotaxis. Genes Dev. 16:2973-84 [Pubmed, PDF]

Park, H.-T, Wu JY*, Rao Y*. (2002) Molecular Control of Neuronal Migration. BioEssays. 24:821-827 [* co-corresponding author] [Pubmed, PDF]

Wong K, Park, H.-T, Wu JY*, Rao Y*. (2002b) Slit Proteins: Guidance Cues for Cells Ranging from Neurons to Leukocytes. Curr Opin Genet Dev. 12:583-591 [* co-corresponding author] [Pubmed, PDF]

Wong K, Wu JY*, Rao Y*. (2002a) Neuronal Migration. in Encyclopedia of Life Sciences (Nature Publishing Group) [* co-corresponding author] [Website, PDF]

Zhu Y, Yu T, Zhang, X, Nagasawa T, Wu JY*, Rao Y*. (2002) Role of the Chemokine SDF-1 as the meningeal attractant for embryonic cerebellar neurons. Nat Neurosci. 5:719-720 [* co-corresponding author] [Pubmed, PDF]

Zhou Y, Zhang W, Easton R, Ray JW, Lampe P, Jiang Z, Brunkan AL, Goate A, Johnson EM, Wu JY*. (2002) Presenilin-1 protects against neuronal apoptosis caused by its interacting protein PAG. Neurobiol Dis. 9:126-138 [Pubmed, PDF]

2001

Wong K, Ren X-R, Huang Y-Z, Xie Y, Liu G, Saito H, Tang H, Wen L, Brady-Kalnay SM, Mei, L, Wu JY, Xiong W-C, Rao Y. (2001) Signal Transduction in Neuronal Migration: Roles of GTPaseActivating Proteins and the Small GTPase Cdc42 in the Slit-Robo Pathway. Cell. 107:209-221 [Pubmed, PDF]

Rao Y*, Wu JY*. (2001) Neuronal Migration and the Evolution of the Human Brain. Nat Neurosci. 4:860-862 [* co-corresponding author] [Pubmed, PDF]

Wu JY*, Feng L*, Park H-T, Havlioglu N, Wen L, Bacon KB, Jiang Z, Tang H, Zhang X-C, Rao, Y*. (2001) The neuronal repellent Slit also inhibits leukocyte chemotaxis induced by chemotactic factors. Nature. 410:948-952 [* co-corresponding author]. [Pubmed, PDF]

Cote J, Dupuis S, Jiang ZH, Wu JY. (2001b) Polypyrimidine track-binding protein binding downstream of caspase-2 alternative exon 9 represses its inclusion. J Biol Chem. 276:8535-8543 [Pubmed, PDF]

Cote J, Dupuis S, Jiang ZH, Wu JY. (2001a) Caspase-2 alternative splicing: identification of a novel intronic element acting as a decoy acceptor site. Proc Natl Acad Sci USA. 98:938-943 [Pubmed, PDF]

2000

1990s

Wu JY, Rao Y. (1999) Fringe: defining borders by regulating the Notch pathway. Curr Opin Neurobiol. 9:537-543 [Pubmed, PDF]

He M, Wen L, Campbell C, Wu JY, Rao Y. (1999) Transcription repression by Xenopus ET and its human ortholog TBX3, a gene involved in ulnar-mammary syndrome. Proc Natl Acad Sci USA. 96:10212-10217 [Pubmed, PDF]

Zhu Y, Li HS, Zhou LJ, Wu JY, Rao Y. (1999) Cellular and molecular guidance of GABAergic neuronal migration from an extracortical origin to the neocortex. Neuron. 23:473-485 [Pubmed, PDF]

Wu W, Wong K, Chen JH, Jiang ZH, Dupuis S, Wu JY*, Rao Y*. (1999) Directional guidance of neuronal migration in the olfactory system by the secreted protein Slit. Nature. 400:331-326 [* co-corresponding author] [Pubmed, PDF]

Li H-S, Chen JH, Wu W, Fagaly T, Zhou L, Dupuis S, Jiang ZH, Nash W, Gick C, Wu JY*, Rao Y*. (1999) Vertebrate Slit, a secreted ligand for the transmembrane protein Roundabout, is a repellent for olfactory bulb axons. Cell. 96:807-818 [* co-corresponding author] [Pubmed, PDF]

Jiang ZH, Wu JY*. (1999). Alternative splicing and programmed cell death. Proc Soc Exp Biol Med. 220:64-72 [Pubmed, Website]

Jiang ZH, Zhang WJ, Rao Y, Wu JY*. (1998) Regulation of Ich-1 pre-mRNA alternative splicing and apoptosis by mammalian splicing factors. Proc. Natl. Acad. Sci. USA. 95:9155-9160 [Pubmed, PDF]

Zhang W-J, Han S-W, McKeel DW, Goate A, Wu JY*. (1998b). Interaction of presenilins with the filamin family of actin-binding proteins. J Neurosci. 18:914-922 [Pubmed, PDF]

Zhang W-J, Wu JY*. (1998a) Sip1, a novel RS domain-containing protein essential for pre-mRNA splicing. Mol Cell Biol. 18:676-684 [Pubmed, PDF]

Li H-S, Tierney C, Wen L, Wu JY, Rao Y. (1997) A single morphogenetic field gives rise to two retina primordia under the influence of the prechordal plate. Development. 124:603-615 [Pubmed, PDF]

Wu JY, Wen L, Zhang W-J, Rao Y. (1996) The secreted product of Xenopus gene lunatic Fringe, a vertebrate signaling molecule. Science. 273:355-358 [Pubmed, PDF]

Zhang W-J, Wu JY*. (1996) The nuclear protein p54 is a novel SR protein active in constitutive and alternative splicing. Mol Cell Biol. 16:5400-5408 [Pubmed, PDF]

Wu JY, Maniatis T. (1993) Specific interactions between proteins implicated in splice site selection and regulated alternative splicing. Cell. 75:1061-70 [Pubmed, PDF]