Skip to main content
Northwestern University Feinberg School of Medicine
ABC Lab

Publications

Learn more about the work that we do in the ABC Laboratory through our recent publications.

 

  1. Gorelick PB, Sorond FA  Stress and Stroke: What, Me Worry?  Neurology  2025 Mar 25;104(6):e213398. doi:10.1212/WNL.0000000000213398
  2. Vedaei F, Srinivasan D, Parker D, Erus G, Dolui S, Sorond FA, Jacobs DR, Launer LJ, Lackland DT, Davatzikos C  et al.  Spatial and signal features of white matter integrity and associations with clinical factors: A CARDIA brain MRI study.  Neuroimage Clin  2025 Mar 14;46:103768. pii:103768
  3. Johnson HR, Wang MC, Stickland RC, Chen Y, Parrish TB, Sorond FA, Bright MG  Variable cerebral blood flow responsiveness to acute hypoxic hypoxia.  Front Physiol  2025;16:1562582. pii:1562582
  4. Nyúl-Tóth Á, Patai R, Csiszar A, Ungvari A, Gulej R, Mukli P, Yabluchanskiy A, Benyo Z, Sotonyi P, Prodan CI  et al.  Linking peripheral atherosclerosis to blood-brain barrier disruption: elucidating its role as a manifestation of cerebral small vessel disease in vascular cognitive impairment.  Geroscience  2024 Dec;46(6):6511-6536. doi:10.1007/s11357-024-01194-0
  5. Johnson HR, Wang MC, Stickland RC, Chen Y, Parrish TB, Sorond FA, Bright MG  Variable Cerebral Blood Flow Responsiveness to Acute Hypoxic Hypoxia.  bioRxiv  2024 Nov 15;. pii:2024.11.14.623430
  6. Duque C, Mahinrad S, Sedaghat S, Higgins J, Milstead A, Sargento-Freitas J, Balabanov R, Cohen B, Sorond FA  Cerebrovascular hemodynamics association with brain structure and function in Multiple Sclerosis.  Mult Scler Relat Disord  2024 Nov;91:105882. doi:10.1016/j.msard.2024.105882
  7. Csiszar A, Ungvari A, Patai R, Gulej R, Yabluchanskiy A, Benyo Z, Kovacs I, Sotonyi P, Kirkpartrick AC, Prodan CI  et al.  Atherosclerotic burden and cerebral small vessel disease: exploring the link through microvascular aging and cerebral microhemorrhages.  Geroscience  2024 Oct;46(5):5103-5132. doi:10.1007/s11357-024-01139-7
  8. Maas MB, Mahinrad S, Sedaghat S, Yaffe K, Launer LJ, Bryan RN, Sidney S, Gorelick PB, Lloyd-Jones DM, Sorond FA  Effects and Thresholds of Young to Midlife Vascular Risks on Brain Health.  Hypertension  2024 Sep;81(9):1935-1944. doi:10.1161/HYPERTENSIONAHA.123.22824
  9. Mukli P, Pinto CB, Owens CD, Csipo T, Lipecz A, Szarvas Z, Peterfi A, Langley ACDCP, Hoffmeister J, Racz FS  et al.  Impaired Neurovascular Coupling and Increased Functional Connectivity in the Frontal Cortex Predict Age-Related Cognitive Dysfunction.  Adv Sci (Weinh)  2024 Mar;11(10):e2303516. pii:2303516
  10. Krefman AE, Stephen J, Carolan P, Sedaghat S, Mansolf M, Soumare A, Gross AL, Aiello AE, Singh-Manoux A, Ikram MA  et al.  Cohort Profile: Dementia Risk Prediction Project (DRPP).  Int J Epidemiol  2024 Feb 01;53(1). pii:dyae012
  11. Romay MC, Knutsen RH, Ma F, Mompeón A, Hernandez GE, Salvador J, Mirkov S, Batra A, Sullivan DP, Procissi D  et al.  Age-related loss of Notch3 underlies brain vascular contractility deficiencies, glymphatic dysfunction, and neurodegeneration in mice.  J Clin Invest  2024 Jan 16;134(2). pii:e166134
  12. Gorelick PB, Sorond FA  What is brain health?  Cereb Circ Cogn Behav  2024;6:100190. pii:100190
  13. Stulberg EL, Sachdev PS, Murray AM, Cramer SC, Sorond FA, Lakshminarayan K, Sabayan B  Post-Stroke Brain Health Monitoring and Optimization: A Narrative Review.  J Clin Med  2023 Nov 29;12(23). pii:7413
  14. Stamm B, Lineback CM, Tang M, Jia DT, Chrenka E, Sorond FA, Sabayan B  Diffusion Restriction in the Splenium: A Comparative Study of Cytotoxic Lesions of the Corpus Callosum (CLOCCs) versus Lesions of Vascular Etiology.  J Clin Med  2023 Nov 08;12(22). pii:6979
  15. Gorelick PB, Sorond FA  Advancing our knowledge about cerebral small vessel diseases.  Lancet Neurol  2023 Nov;22(11):972-973. doi:10.1016/S1474-4422(23)00318-6
  16. Mahinrad S, Bennett DA, Sorond FA, Gorelick PB  Blood pressure variability, dementia, and role of antihypertensive medications in older adults.  Alzheimers Dement  2023 Jul;19(7):2966-2974. doi:10.1002/alz.12935
  17. Sabayan B, Doyle S, Rost NS, Sorond FA, Lakshminarayan K, Launer LJ  The role of population-level preventive care for brain health in ageing.  Lancet Healthy Longev  2023 Jun;4(6):e274-e283. doi:10.1016/S2666-7568(23)00051-X
  18. Chow FC, Zhao F, He Y, Song X, Zhang J, Ao D, Wu Y, Hou B, Sorond FA, Ances BM  et al.  Brief Report: Sex Differences in the Association Between Cerebrovascular Function and Cognitive Health in People Living With HIV in Urban China.  J Acquir Immune Defic Syndr  2023 Mar 01;92(3):217-222. doi:10.1097/QAI.0000000000003127
  19. Yang Y, Knol MJ, Wang R, Mishra A, Liu D, Luciano M, Teumer A, Armstrong N, Bis JC, Jhun MA  et al.  Epigenetic and integrative cross-omics analyses of cerebral white matter hyperintensities on MRI.  Brain  2023 Feb 13;146(2):492-506. doi:10.1093/brain/awac290
  20. Sorond FA, Gorelick PB  Brain Reserve, Resilience, and Cognitive Stimulation Across the Lifespan: How Do These Factors Influence Risk of Cognitive Impairment and the Dementias?  Clin Geriatr Med  2023 Feb;39(1):151-160. doi:10.1016/j.cger.2022.08.003
  21. Mahinrad S, Tan CO, Ma Y, Aristova M, Milstead AL, Lloyd-Jones D, Schnell S, Markl M, Sorond FA  Intracranial Blood Flow Quantification by Accelerated Dual-venc 4D Flow MRI: Comparison With Transcranial Doppler Ultrasound.  J Magn Reson Imaging  2022 Oct;56(4):1256-1264. doi:10.1002/jmri.28115
  22. Sorond FA  Mediterranean Diet and Brain Health in Hispanic or Latino Adults.  JAMA Netw Open  2022 Jul 01;5(7):e2221989. doi:10.1001/jamanetworkopen.2022.21989
  23. Muratoglu SC, Charette MF, Galis ZS, Greenstein AS, Daugherty A, Joutel A, Kozel BA, Wilcock DM, Collins EC, Sorond FA  et al.  Perspectives on Cognitive Phenotypes and Models of Vascular Disease.  Arterioscler Thromb Vasc Biol  2022 Jul;42(7):831-838. doi:10.1161/ATVBAHA.122.317395
  24. Whitehead SN, Bruno A, Burns JM, Carmichael ST, Csiszar A, Edwards JD, Elahi FM, Faraco G, Gould DB, Gustafson DR  et al.  Expanding the horizon of research into the pathogenesis of the white matter diseases: Proceedings of the 2021 Annual Workshop of the Albert Research Institute for White Matter and Cognition.  Geroscience  2022 Feb;44(1):25-37. doi:10.1007/s11357-021-00461-8
  25. Mahinrad S, Sorond FA, Gorelick PB  Hypertension and cognitive dysfunction: a review of mechanisms, life-course observational studies and clinical trial results.  Rev Cardiovasc Med  2021 Dec 22;22(4):1429-1449. doi:10.31083/j.rcm2204148
  26. Csipo T, Lipecz A, Owens C, Mukli P, Perry JW, Tarantini S, Balasubramanian P, Nyúl-Tóth Á, Yabluchanska V, Sorond FA  et al.  Sleep deprivation impairs cognitive performance, alters task-associated cerebral blood flow and decreases cortical neurovascular coupling-related hemodynamic responses.  Sci Rep  2021 Oct 25;11(1):20994. pii:20994
  27. Mukli P, Csipo T, Lipecz A, Stylianou O, Racz FS, Owens CD, Perry JW, Tarantini S, Sorond FA, Kellawan JM  et al.  Sleep deprivation alters task-related changes in functional connectivity of the frontal cortex: A near-infrared spectroscopy study.  Brain Behav  2021 Aug;11(8):e02135. pii:e02135
  28. Mahinrad S, Shownkeen M, Sedaghat S, Yaffe K, Hausdorff JM, Lloyd-Jones DM, Gorelick PB, Sorond FA  Vascular health across young adulthood and midlife cerebral autoregulation, gait, and cognition.  Alzheimers Dement  2021 May;17(5):745-754. doi:10.1002/alz.12246
  29. Batra A, Clark JR, LaHaye K, Shlobin NA, Hoffman SC, Orban ZS, Colton K, Dematte JE, Sorond FA, Koralnik IJ  et al.  Transcranial Doppler Ultrasound Evidence of Active Cerebral Embolization in COVID-19.  J Stroke Cerebrovasc Dis  2021 Mar;30(3):105542. doi:10.1016/j.jstrokecerebrovasdis.2020.105542
  30. Chow FC, Ma Y, Manion M, Rupert A, Lambert-Messerlian G, Bushnell CD, Cedars MI, Sereti I, Sorond FA, Hsue PY  et al.  Factors associated with worse cerebrovascular function in aging women with and at risk for HIV.  AIDS  2021 Feb 02;35(2):257-266. doi:10.1097/QAD.0000000000002755
  31. Hextrum S, Minhas JS, Liotta EM, Sorond FA, Naidech AM, Maas MB  Hypocapnia, ischemic lesions, and outcomes after intracerebral hemorrhage.  J Neurol Sci  2020 Nov 15;418:117139. doi:10.1016/j.jns.2020.117139
  32. Das AS, Regenhardt RW, LaRose S, Monk AD, Castro PM, Sheriff FG, Sorond FA, Vaitkevicius H  Microembolic Signals Detected by Transcranial Doppler Predict Future Stroke and Poor Outcomes.  J Neuroimaging  2020 Nov;30(6):882-889. doi:10.1111/jon.12749
  33. Mahinrad S, Sabayan B, Garner CR, Lloyd-Jones DM, Sorond FA  N-Terminal Pro Brain, N-Terminal Pro Atrial Natriuretic Peptides, and Dynamic Cerebral Autoregulation.  J Am Heart Assoc  2020 Oct 20;9(20):e018203. pii:e018203
  34. Liotta EM, Karvellas CJ, Kim M, Batra A, Naidech A, Prabhakaran S, Sorond FA, Kimberly WT, Maas MB  Serum osmolality, cerebrospinal fluid specific gravity and overt hepatic encephalopathy severity in patients with liver failure.  Liver Int  2020 Aug;40(8):1977-1986. doi:10.1111/liv.14400
  35. Jor'dan AJ, Manor B, Iloputaife I, Habtemariam DA, Bean JF, Sorond FA, Lipsitz LA  Diminished Locomotor Control Is Associated With Reduced Neurovascular Coupling in Older Adults.  J Gerontol A Biol Sci Med Sci  2020 Jul 13;75(8):1516-1522. doi:10.1093/gerona/glz006
  36. Jenkins LM, Garner CR, Kurian S, Higgins JP, Parrish TB, Sedaghat S, Nemeth AJ, Lloyd-Jones DM, Launer LJ, Hausdorff JM  et al.  Cumulative Blood Pressure Exposure, Basal Ganglia, and Thalamic Morphology in Midlife.  Hypertension  2020 May;75(5):1289-1295. doi:10.1161/HYPERTENSIONAHA.120.14678
  37. Nadkarni NA, Maas MB, Batra A, Kim M, Manno EM, Sorond FA, Prabhakaran S, Naidech AM, Liotta EM  Elevated Cerebrospinal Fluid Protein Is Associated with Unfavorable Functional Outcome in Spontaneous Subarachnoid Hemorrhage.  J Stroke Cerebrovasc Dis  2020 Apr;29(4):104605. doi:10.1016/j.jstrokecerebrovasdis.2019.104605
  38. Mahinrad S, Kurian S, Garner CR, Sedaghat S, Nemeth AJ, Moscufo N, Higgins JP, Jacobs DR, Hausdorff JM, Lloyd-Jones DM  et al.  Cumulative Blood Pressure Exposure During Young Adulthood and Mobility and Cognitive Function in Midlife.  Circulation  2020 Mar 03;141(9):712-724. doi:10.1161/CIRCULATIONAHA.119.042502
  39. Sorond FA, Whitehead S, Arai K, Arnold D, Carmichael ST, De Carli C, Duering M, Fornage M, Flores-Obando RE, Graff-Radford J  et al.  Proceedings from the Albert Charitable Trust Inaugural Workshop on white matter and cognition in aging.  Geroscience  2020 Feb;42(1):81-96. doi:10.1007/s11357-019-00141-8
  40. Kim M, Liotta EM, Zee PC, Ganger DR, Ladner DP, Karmarkar A, Peipert JD, Sorond FA, Prabhakaran S, Reid KJ  et al.  Impaired cognition predicts the risk of hospitalization and death in cirrhosis.  Ann Clin Transl Neurol  2019 Nov;6(11):2282-2290. doi:10.1002/acn3.50924
  41. Csipo T, Mukli P, Lipecz A, Tarantini S, Bahadli D, Abdulhussein O, Owens C, Kiss T, Balasubramanian P, Nyúl-Tóth Á  et al.  Assessment of age-related decline of neurovascular coupling responses by functional near-infrared spectroscopy (fNIRS) in humans.  Geroscience  2019 Oct;41(5):495-509. doi:10.1007/s11357-019-00122-x
  42. Purkayastha S, Sorond FA, Lyng S, Frantz J, Murphy MN, Hynan LS, Sabo T, Bell KR  Impaired Cerebral Vasoreactivity Despite Symptom Resolution in Sports-Related Concussion.  J Neurotrauma  2019 Aug 15;36(16):2385-2390. doi:10.1089/neu.2018.5861
  43. Sorond FA, Gorelick PB  Brain White Matter: A Substrate for Resilience and a Substance for Subcortical Small Vessel Disease.  Brain Sci  2019 Aug 08;9(8). pii:193
  44. Swor DE, Thomas LF, Maas MB, Grimaldi D, Manno EM, Sorond FA, Batra A, Kim M, Prabhakaran S, Naidech AM  et al.  Admission Heart Rate Variability is Associated with Fever Development in Patients with Intracerebral Hemorrhage.  Neurocrit Care  2019 Apr;30(2):244-250. doi:10.1007/s12028-019-00684-w
  45. Caprio FZ, Sorond FA  Cerebrovascular Disease: Primary and Secondary Stroke Prevention.  Med Clin North Am  2019 Mar;103(2):295-308. doi:10.1016/j.mcna.2018.10.001
  46. Maas MB, Naidech AM, Kim M, Batra A, Manno EM, Sorond FA, Prabhakaran S, Liotta EM  Medication History versus Point-of-Care Platelet Activity Testing in Patients with Intracerebral Hemorrhage.  J Stroke Cerebrovasc Dis  2018 May;27(5):1167-1173. doi:10.1016/j.jstrokecerebrovasdis.2017.11.033
  47. Brooks FA, Ughwanogho U, Henderson GV, Black-Schaffer R, Sorond FA, Tan CO  The Link Between Cerebrovascular Hemodynamics and Rehabilitation Outcomes After Aneurysmal Subarachnoid Hemorrhage.  Am J Phys Med Rehabil  2018 May;97(5):309-315. doi:10.1097/PHM.0000000000000886
  48. Gallagher TK, Thomas KA, Ladner DP, Ganger D, Sorond FA, Prabhakaran S, Abecassis MM, Fryer JP, Liotta EM  Incidence and Risk Factors of Intracranial Hemorrhage in Liver Transplant Recipients.  Transplantation  2018 Mar;102(3):448-453. doi:10.1097/TP.0000000000002005
  49. Liotta EM, Romanova AL, Lizza BD, Rasmussen-Torvik LJ, Kim M, Francis B, Sangha RS, Carroll TJ, Ganger D, Ladner DP  et al.  Osmotic Shifts, Cerebral Edema, and Neurologic Deterioration in Severe Hepatic Encephalopathy.  Crit Care Med  2018 Feb;46(2):280-289. doi:10.1097/CCM.0000000000002831
  50. Hood R, Budd A, Sorond FA, Hogue CW  Peri-operative neurological complications.  Anaesthesia  2018 Jan;73 Suppl 1:67-75. doi:10.1111/anae.14142