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Learn more about the work that we do in the Behavioral Sleep Medicine Lab through our recent publications.

  1. Ong JCL, Chang SY, William W, Butte AJ, Shah NH, Chew LST, Liu N, Doshi-Velez F, Lu W, Savulescu J  et al.  Ethical and regulatory challenges of large language models in medicine.  Lancet Digit Health  2024 Apr 23;. pii:S2589-7500(24)00061-X
  2. Rehm A, Newton AC, Hatzantoni K, Linardatou Novak P, Ong JCY, Ashby E  Arthroscopically assisted closed reduction for displaced lateral humeral condyle fractures over 4 mm in children.  Injury  2024 Apr 17;55(6):111575. doi:10.1016/j.injury.2024.111575
  3. Rehm A, Linardatou Novak P, Kobezda T, Ong JCY, Thahir A, Ashby E  Resource implications of managing paediatric femoral fractures in a major trauma centre: Analysis of 98 cases.  Injury  2024 Mar;55(3):111250. doi:10.1016/j.injury.2023.111250
  4. Schotland H, Wickwire E, Aaronson RM, Dawson SC, Khosla S, Lee-Iannotti JK, Leu RM, Lewin DS, McCrae CS, Neubauer D  et al.  Increasing access to evidence-based insomnia care in the United States: findings from an American Academy of Sleep Medicine stakeholder summit.  J Clin Sleep Med  2024 Mar 01;20(3):455-459. doi:10.5664/jcsm.10922
  5. Kalmbach DA, Reffi AN, Ong JC, Cheng P, Walch O, Pitts DS, Seymour GM, Hirata M, Roth A, Roth T  et al.  Preliminary evidence of psychological improvements and increased maternal-fetal attachment associated with a mindfulness sleep programme: secondary analysis of uncontrolled data in 11 pregnant women with insomnia disorder.  J Sleep Res  2024 Feb;33(1):e14040. doi:10.1111/jsr.14040
  6. Ong JCL, Seng BJJ, Law JZF, Low LL, Kwa ALH, Giacomini KM, Ting DSW  Artificial intelligence, ChatGPT, and other large language models for social determinants of health: Current state and future directions.  Cell Rep Med  2024 Jan 16;5(1):101356. pii:101356
  7. Goh KJ, Chew WM, Ong JCL, Leong CK, Mohamed Noor IB, Anantham D, Hui LYS, Choong MCM, Liew CJY, Gutierrez MT  et al.  A Retrospective Cohort Study Evaluating the Safety and Efficacy of Sequential versus Concurrent Intrapleural Instillation of Tissue Plasminogen Activator and DNase for Pleural Infection.  Pulm Med  2023;2023:6340851. pii:6340851
  8. Li Y, Gunasekeran DV, RaviChandran N, Tan TF, Ong JCL, Thirunavukarasu AJ, Polascik BW, Habash R, Khaderi K, Ting DS  The next generation of healthcare ecosystem in the metaverse.  Biomed J  2023 Dec 02;:100679. doi:10.1016/
  9. Soon JJY, Juan DWK, Ong WS, Bek S, Neo PSH, Salazar E, Da Zhuang K, Tan YP, Seo CJ, Ong JCA  et al.  Implementation of a Multi-Disciplinary Team and Quality of Goals of Care Discussions in Palliative Surgical Oncology Patients.  Ann Surg Oncol  2023 Dec;30(13):8054-8060. doi:10.1245/s10434-023-14190-z
  10. Tang NKY, Saconi B, Jansson-Fröjmark M, Ong JC, Carney CE  Cognitive factors and processes in models of insomnia: A systematic review.  J Sleep Res  2023 Dec;32(6):e13923. pii:e13923
  11. Mundt JM, Schuiling MD, Warlick C, Dietch JR, Wescott AB, Hagenaars M, Furst A, Khorramdel K, Baron KG  Behavioral and psychological treatments for NREM parasomnias: A systematic review.  Sleep Med  2023 Nov;111:36-53. doi:10.1016/j.sleep.2023.09.004
  12. Ng FYC, Thirunavukarasu AJ, Cheng H, Tan TF, Gutierrez L, Lan Y, Ong JCL, Chong YS, Ngiam KY, Ho D  et al.  Artificial intelligence education: An evidence-based medicine approach for consumers, translators, and developers.  Cell Rep Med  2023 Oct 17;4(10):101230. pii:101230
  13. Liu M, Ning Y, Teixayavong S, Mertens M, Xu J, Ting DSW, Cheng LT, Ong JCL, Teo ZL, Tan TF  et al.  A translational perspective towards clinical AI fairness.  NPJ Digit Med  2023 Sep 14;6(1):172. pii:172
  14. Turner AD, Ong JC, Jones AL, Tu A, Salanitro M, Crawford MR  Neurocognitive functioning in comorbid insomnia and sleep apnea patients is better after positive airway pressure therapy, but worse after cognitive behavioral therapy for insomnia: exploratory analysis of cognitive outcomes from the Multidisciplinary Approach to the Treatment of Insomnia and Comorbid Sleep Apnea study.  Sleep  2023 Aug 14;46(8). pii:zsad128
  15. Kalmbach DA, Cheng P, Reffi AN, Ong JC, Swanson LM, Espie CA, Seymour GM, Hirata M, Walch O, Pitts DS  et al.  Reducing cognitive arousal and sleep effort alleviates insomnia and depression in pregnant women with DSM-5 insomnia disorder treated with a mindfulness sleep program.  Sleep Adv  2023;4(1):zpad031. pii:zpad031
  16. Kalmbach DA, Cheng P, Reffi AN, Ong JC, Swanson LM, Fresco DM, Walch O, Seymour GM, Fellman-Couture C, Bayoneto AD  et al.  Perinatal Understanding of Mindful Awareness for Sleep (PUMAS): A single-arm proof-of-concept clinical trial of a mindfulness-based intervention for DSM-5 insomnia disorder during pregnancy.  Sleep Med  2023 Aug;108:79-89. doi:10.1016/j.sleep.2023.05.026
  17. Ong JCM, Than H, Tripathi S, Gkitzia C, Wang X  A cost-effectiveness analysis of ruxolitinib versus best alternative therapy for patients with steroid-refractory chronic graft-versus-host disease aged > 12 years in Singapore.  Cost Eff Resour Alloc  2023 May 31;21(1):34. pii:34
  18. Ong JC, Kalmbach DA  Mindfulness as an Adjunct or Alternative to CBT-I.  Sleep Med Clin  2023 Mar;18(1):59-71. doi:10.1016/j.jsmc.2022.09.002
  19. Rehm A, Ashby E, Thahir A, Ngu AWT, Kobezda T, Ong JCY, Granger L  The incidence of congenital pseudarthrosis of the clavicle and review of the literature.  J Pediatr Orthop B  2023 Mar 01;32(2):185-191. doi:10.1097/BPB.0000000000001024
  20. Ong JC, Dawson SC, Taylor HL, Park M, Burgess HJ, Crawford MR, Rains JC, Smitherman TA, Espie CA, Jones AL  et al.  A Micro-Longitudinal Study of Naps, Sleep Disturbance, and Headache Severity in Women with Chronic Migraine.  Behav Sleep Med  2023;21(2):117-128. doi:10.1080/15402002.2022.2050723
  21. Perini F, Wong KF, Lin J, Hassirim Z, Ong JL, Lo J, Ong JC, Doshi K, Lim J  Mindfulness-based therapy for insomnia for older adults with sleep difficulties: a randomized clinical trial.  Psychol Med  2023 Feb;53(3):1038-1048. doi:10.1017/S0033291721002476
  22. Han S, Chok AY, Peh DYY, Ho JZ, Tan EKW, Koo SL, Tan IB, Ong JC  The distinct clinical trajectory, metastatic sites, and immunobiology of microsatellite-instability-high cancers.  Front Genet  2022;13:933475. pii:933475
  23. Rehm A, Ngu AWT, Ong JCY, Ashby E  Does Surgical Experience Decrease Radiation Exposure in the Operating Room?  J Pediatr Orthop  2022 Sep 01;42(8):e910. doi:10.1097/BPO.0000000000002153
  24. Rehm A, Ashby E, Granger L, Ong JCY  Comparison of lateral entry and crossed entry pinning for pediatric supracondylar humerus fractures: a meta-analysis of randomized controlled trials.  J Orthop Surg Res  2022 Aug 19;17(1):394. pii:394
  25. Wong KF, Perini F, Lin J, Goldstein M, Ong JL, Lo J, Ong JC, Doshi K, Lim J  Dissociable changes in sleep architecture with mindfulness and sleep hygiene intervention in older adults: Secondary and exploratory analysis of polysomnography data from the Mindfulness Sleep Therapy (MIST) trial.  Sleep Health  2022 Aug;8(4):364-372. doi:10.1016/j.sleh.2022.02.003
  26. Rehm A, Granger L, Kobezda T, Ong JCY  Letter to the Editor: "Fixation of Unstable Osteochondritis Dissecans Lesions and Displaced Osteochondral Fragments Using New Biodegradable Magnesium Pins in Adolescents".  Cartilage  2022;13(3):19476035221098874. pii:19476035221098874
  27. Rehm A, Granger L, Ong JCY, Ashby E  "Safety and performance of biodegradable magnesium-based implants in children and adolescents".  Injury  2022 Jun;53(6):2380-2381. doi:10.1016/j.injury.2022.01.010
  28. Rehm A, Ong JCY, Kobezda T, Granger L  Lateral entry pins and Slongo's external fixation: which method is more ideal for older children with supracondylar humeral fractures?  J Orthop Surg Res  2022 Apr 07;17(1):208. pii:208
  29. Chua NG, Loo L, Hee DKH, Lim TP, Ng TM, Hoo GSR, Soong JL, Ong JCL, Tang SSL, Zhou YP  et al.  Therapeutic drug monitoring of meropenem and piperacillin-tazobactam in the Singapore critically ill population - A prospective, multi-center, observational study (BLAST 1).  J Crit Care  2022 Apr;68:107-113. doi:10.1016/j.jcrc.2021.12.013
  30. Fox RS, Gaumond JS, Zee PC, Kaiser K, Tanner EJ, Ancoli-Israel S, Siddique J, Penedo FJ, Wu LM, Reid KJ  et al.  Optimizing a Behavioral Sleep Intervention for Gynecologic Cancer Survivors: Study Design and Protocol.  Front Neurosci  2022;16:818718. pii:818718
  31. Rehm A, Kobezda T, Ong JCY, Ashby E  "Changes in the management of pediatric medial humeral epicondyle fractures with and without associated elbow dislocation." Scherer S, Dietzel M, Jordan N, Tsiflikas I, Kirschner HJ, Fuchs J, Lieber J. Injury 2021;52:2257-2264.  Injury  2022 Mar;53(3):1297-1298. doi:10.1016/j.injury.2021.11.059
  32. Tu AY, Crawford MR, Dawson SC, Fogg LF, Turner AD, Wyatt JK, Crisostomo MI, Chhangani BS, Kushida CA, Edinger JD  et al.  A randomized controlled trial of cognitive behavioral therapy for insomnia and PAP for obstructive sleep apnea and comorbid insomnia: effects on nocturnal sleep and daytime performance.  J Clin Sleep Med  2022 Mar 01;18(3):789-800. doi:10.5664/jcsm.9696
  33. Rehm A, Ong JCY, Kobezda T, Ashby E  Application of ultrasound in the closed reduction and percutaneous pinning in supracondylar humeral fractures.  J Orthop Surg Res  2022 Feb 11;17(1):84. pii:84
  34. Rehm A, Ong JCY, Ashby E  Clinical value of MRI in evaluating and diagnosing of humeral lateral condyle fracture in children.  J Orthop Surg Res  2022 Jan 06;17(1):10. pii:10
  35. Rehm A, Ong JCY, Ashby E  "Open Reduction of Medial Epicondyle Fractures in the Pediatric Population: Supine Versus Prone Position".  J Pediatr Orthop  2022 Jan 01;42(1):e100-e101. doi:10.1097/BPO.0000000000001991
  36. von Schantz M, Ong JC, Knutson KL  Associations between sleep disturbances, diabetes and mortality in the UK Biobank cohort: A prospective population-based study.  J Sleep Res  2021 Dec;30(6):e13392. pii:e13392
  37. Grimaldi D, Reid KJ, Papalambros NA, Braun RI, Malkani RG, Abbott SM, Ong JC, Zee PC  Autonomic dysregulation and sleep homeostasis in insomnia.  Sleep  2021 Jun 11;44(6). pii:zsaa274
  38. Mundt JM, Baron KG  Integrative behavioral treatment for NREM parasomnias: a case series.  J Clin Sleep Med  2021 Jun 01;17(6):1313-1316. doi:10.5664/jcsm.9186
  39. Ong JC, Crawford MR, Wallace DM  Sleep Apnea and Insomnia: Emerging Evidence for Effective Clinical Management.  Chest  2021 May;159(5):2020-2028. doi:10.1016/j.chest.2020.12.002
  40. Ong JC, Fox RS, Brower RF, Mazurek S, Moore C  How Does Narcolepsy Impact Health-Related Quality of Life? A Mixed-Methods Study.  Behav Sleep Med  2021;19(2):145-158. doi:10.1080/15402002.2020.1715411
  41. Fox RS, Baik SH, McGinty H, Garcia SF, Reid KJ, Bovbjerg K, Fajardo P, Wu LM, Shahabi S, Ong JC  et al.  Feasibility and Preliminary Efficacy of a Bright Light Intervention in Ovarian and Endometrial Cancer Survivors.  Int J Behav Med  2021 Feb;28(1):83-95. doi:10.1007/s12529-020-09861-0
  42. Ong JC, Dawson SC, Mundt JM, Moore C  Developing a cognitive behavioral therapy for hypersomnia using telehealth: a feasibility study.  J Clin Sleep Med  2020 Dec 15;16(12):2047-2062. doi:10.5664/jcsm.8750
  43. Wan KR, Qiu L, Saffari SE, Khong WXL, Ong JCL, See AA, Ng WH, King NKK  An open label randomized trial to assess the efficacy of tranexamic acid in reducing post-operative recurrence of chronic subdural haemorrhage.  J Clin Neurosci  2020 Dec;82(Pt A):147-154. doi:10.1016/j.jocn.2020.10.053
  44. Gill JR, Vermuyten L, Schenk SA, Ong JCY, Schenk W  Olecranon fixation with two bicortical screws.  Bone Jt Open  2020 Jul;1(7):376-382. doi:10.1302/2633-1462.17.BJO-2020-0069.R1
  45. Trotti LM, Ong JC, Plante DT, Friederich Murray C, King R, Bliwise DL  Disease symptomatology and response to treatment in people with idiopathic hypersomnia: initial data from the Hypersomnia Foundation registry.  Sleep Med  2020 Nov;75:343-349. doi:10.1016/j.sleep.2020.08.034
  46. Chin KM, Tan GHC, Chia CS, Ong JCA, Teo MCC  Novel prognostic score for outcomes after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for colorectal cancer with metachronous peritoneal carcinomatosis.  ANZ J Surg  2020 Oct;90(10):1958-1964. doi:10.1111/ans.15783
  47. Ong JC, Crawford MR, Dawson SC, Fogg LF, Turner AD, Wyatt JK, Crisostomo MI, Chhangani BS, Kushida CA, Edinger JD  et al.  A randomized controlled trial of CBT-I and PAP for obstructive sleep apnea and comorbid insomnia: main outcomes from the MATRICS study.  Sleep  2020 Sep 14;43(9). pii:zsaa041
  48. Ong JC, Gamaldo C  Optimizing Behavioral Sleep Strategies.  Continuum (Minneap Minn)  2020 Aug;26(4):1075-1081. doi:10.1212/CON.0000000000000876
  49. Ong JC, Moore C  What do we really know about mindfulness and sleep health?  Curr Opin Psychol  2020 Aug;34:18-22. doi:10.1016/j.copsyc.2019.08.020
  50. Ong JC, Tu AY  Nocturnal cognitive arousal: evidence for 24-h hyperarousal?  Sleep Med  2020 Jul;71:149-150. doi:10.1016/j.sleep.2020.01.001