Publications
- Maddineni A, Liang Z, Jambardi S, Roy S, Tycko J, Patil A, Manzano M, Gottwein E
Cytotoxicity of Activator Expression in CRISPR-based Transcriptional Activation Systems.
bioRxiv
2024 Sep 23;. pii:2024.09.23.614524
- Kuehnle N, Osborne SM, Liang Z, Manzano M, Gottwein E
CRISPR screens identify novel regulators of cFLIP dependency and ligand-independent, TRAIL-R1-mediated cell death.
Cell Death Differ
2023 May;30(5):1221-1234. doi:10.1038/s41418-023-01133-0
- Kuehnle N, Gottwein E
Druggable host gene dependencies in primary effusion lymphoma.
Curr Opin Virol
2022 Oct;56:101270. doi:10.1016/j.coviro.2022.101270
- Wang C, Zhang L, Ke L, Ding W, Jiang S, Li D, Narita Y, Hou I, Liang J, Li S et al.
Primary effusion lymphoma enhancer connectome links super-enhancers to dependency factors.
Nat Commun
2020 Dec 09;11(1):6318. pii:6318
- Manzano M, Günther T, Ju H, Nicholas J, Bartom ET, Grundhoff A, Gottwein E
Kaposi's Sarcoma-Associated Herpesvirus Drives a Super-Enhancer-Mediated Survival Gene Expression Program in Primary Effusion Lymphoma.
mBio
2020 Aug 25;11(4). pii:e01457-20
- Morrison K, Manzano M, Chung K, Schipma MJ, Bartom ET, Gottwein E
The Oncogenic Kaposi's Sarcoma-Associated Herpesvirus Encodes a Mimic of the Tumor-Suppressive miR-15/16 miRNA Family.
Cell Rep
2019 Dec 03;29(10):2961-2969.e6. doi:10.1016/j.celrep.2019.11.005
- Patil A, Manzano M, Gottwein E
Genome-wide CRISPR screens reveal genetic mediators of cereblon modulator toxicity in primary effusion lymphoma.
Blood Adv
2019 Jul 23;3(14):2105-2117. doi:10.1182/bloodadvances.2019031732