Northwestern University Feinberg School of Medicine

Eva Gottwein Lab


  1. Manzano M, Patil A, Waldrop A, Dave SS, Behdad A, Gottwein E  Gene essentiality landscape and druggable oncogenic dependencies in herpesviral primary effusion lymphoma.  Nat Commun  2018 Aug 15;9(1):3263. doi:10.1038/s41467-018-05506-9
  2. Patil A, Manzano M, Gottwein E  CK1α and IRF4 are essential and independent effectors of immunomodulatory drugs in primary effusion lymphoma.  Blood  2018 Aug 09;132(6):577-586. doi:10.1182/blood-2018-01-828418
  3. Manzano M, Forte E, Raja AN, Schipma MJ, Gottwein E  Divergent target recognition by coexpressed 5'-isomiRs of miR-142-3p and selective viral mimicry.  RNA  2015 Sep;21(9):1606-20. doi:10.1261/rna.048876.114
  4. Forte E, Raja AN, Shamulailatpam P, Manzano M, Schipma MJ, Casey JL, Gottwein E  MicroRNA-mediated transformation by the Kaposi's sarcoma-associated herpesvirus Kaposin locus.  J Virol  2015 Feb;89(4):2333-41. doi:10.1128/JVI.03317-14
  5. Grosswendt S, Filipchyk A, Manzano M, Klironomos F, Schilling M, Herzog M, Gottwein E, Rajewsky N  Unambiguous identification of miRNA:target site interactions by different types of ligation reactions.  Mol Cell  2014 Jun 19;54(6):1042-1054. doi:10.1016/j.molcel.2014.03.049
  6. Khare S, Ratsimandresy RA, de Almeida L, Cuda CM, Rellick SL, Misharin AV, Wallin MC, Gangopadhyay A, Forte E, Gottwein E, Perlman H, Reed JC, Greaves DR, Dorfleutner A, Stehlik C  The PYRIN domain-only protein POP3 inhibits ALR inflammasomes and regulates responses to infection with DNA viruses.  Nat Immunol  2014 Apr;15(4):343-53. doi:10.1038/ni.2829
  7. Manzano M, Shamulailatpam P, Raja AN, Gottwein E  Kaposi's sarcoma-associated herpesvirus encodes a mimic of cellular miR-23.  J Virol  2013 Nov;87(21):11821-30. doi:10.1128/JVI.01692-13
  8. Gottwein E  Roles of microRNAs in the life cycles of mammalian viruses.  Curr Top Microbiol Immunol  2013;371:201-27. doi:10.1007/978-3-642-37765-5_8