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Northwestern University Feinberg School of Medicine
Duncan Lab

Publications

Learn more about the work that we do in the Duncan Lab through our 50 most recent publications linked below or visit Dr. Duncan’s faculty profile.

  1. Zhou LT, Gokyer D, Madkins K, Beestrum M, Horton DE, Duncan FE, Babayev E  The Effects of Heat Stress on the Ovary, Follicles and Oocytes: A Systematic Review.  bioRxiv  2024 Dec 05;. pii:2024.12.04.626831
  2. Converse A, Perry MJ, Dipali SS, Isola JVV, Kelly EB, Varberg JM, Zelinski MB, Gerton JL, Stout MB, Pritchard MT  et al.  Multinucleated giant cells are hallmarks of ovarian aging with unique immune and degradation-associated molecular signatures.  bioRxiv  2024 Dec 05;. pii:2024.12.03.626649
  3. Balough JL, Dipali SS, Velez K, Kumar TR, Duncan FE  Hallmarks of female reproductive aging in physiologic aging mice.  Nat Aging  2024 Dec;4(12):1711-1730. doi:10.1038/s43587-024-00769-y
  4. Suryadevara V, Hudgins AD, Rajesh A, Pappalardo A, Karpova A, Dey AK, Hertzel A, Agudelo A, Rocha A, Soygur B  et al.  SenNet recommendations for detecting senescent cells in different tissues.  Nat Rev Mol Cell Biol  2024 Dec;25(12):1001-1023. doi:10.1038/s41580-024-00738-8
  5. Yano Maher JC, Zelinski MB, Oktay KH, Duncan FE, Segars JH, Lujan ME, Lou H, Yun BH, Hanfling SN, Schwartz LE  et al.  Classification system of human ovarian follicle morphology: recommendations of the National Institute of Child Health and Human Development - sponsored ovarian nomenclature workshop.  Fertil Steril  2024 Nov 15;. pii:S0015-0282(24)02394-X
  6. Bomba-Warczak EK, Velez KM, Zhou LT, Guillermier C, Edassery S, Steinhauser ML, Savas JN, Duncan FE  Exceptional longevity of mammalian ovarian and oocyte macromolecules throughout the reproductive lifespan.  Elife  2024 Oct 31;13. pii:RP93172
  7. Zaniker EJ, Zhang J, Russo D, Huang R, Suritis K, Drake RS, Barlow-Smith E, Shalek AK, Woodruff TK, Xiao S  et al.  Follicle-intrinsic and spatially distinct molecular programs drive follicle rupture and luteinization during ex vivo mammalian ovulation.  Commun Biol  2024 Oct 23;7(1):1374. pii:1374
  8. Amargant F, Magalhaes C, Pritchard MT, Duncan FE  Systemic low-dose anti-fibrotic treatment attenuates ovarian aging in the mouse.  Geroscience  2024 Sep 16;. doi:10.1007/s11357-024-01322-w
  9. Dipali SS, Gowett MQ, Kamat P, Converse A, Zaniker EJ, Fennell A, Chou T, Pritchard MT, Zelinski M, Phillip JM  et al.  Self-organizing ovarian somatic organoids preserve cellular heterogeneity and reveal cellular contributions to ovarian aging.  bioRxiv  2024 Aug 10;. pii:2024.08.10.607456
  10. Gokyer D, Akinboro S, Zhou LT, Kleinhans A, Laronda MM, Duncan FE, Riley JK, Goldman KN, Babayev E  The oocyte microenvironment is altered in adolescents compared to oocyte donors.  Hum Reprod Open  2024;2024(3):hoae047. pii:hoae047
  11. Wu H, Nguyen H, Hashim PH, Fogelgren B, Duncan FE, Ward WS  Oocyte-specific EXOC5 expression is required for mouse oogenesis and folliculogenesis.  Mol Hum Reprod  2024 Aug 05;30(8). pii:gaae026
  12. Zaniker EJ, Hashim PH, Gauthier S, Ankrum JA, Campo H, Duncan FE  Three-Dimensionally Printed Agarose Micromold Supports Scaffold-Free Mouse Ex Vivo Follicle Growth, Ovulation, and Luteinization.  Bioengineering (Basel)  2024 Jul 15;11(7). pii:719
  13. Amargant F, Vieira C, Pritchard MT, Duncan FE  Systemic low-dose anti-fibrotic treatment attenuates ovarian aging in the mouse.  bioRxiv  2024 Jun 25;. pii:2024.06.21.600035
  14. Zaniker EJ, Zhang M, Hughes L, La Follette L, Atazhanova T, Trofimchuk A, Babayev E, Duncan FE  Shear wave elastography to assess stiffness of the human ovary and other reproductive tissues across the reproductive lifespan in health and disease†.  Biol Reprod  2024 Jun 12;110(6):1100-1114. doi:10.1093/biolre/ioae050
  15. Huang R, Kratka CE, Pea J, McCann C, Nelson J, Bryan JP, Zhou LT, Russo DD, Zaniker EJ, Gandhi AH  et al.  Single-cell and spatiotemporal profile of ovulation in the mouse ovary.  bioRxiv  2024 Jun 05;. pii:2024.05.20.594719
  16. Zhu Y, Kratka CR, Pea J, Lee HC, Kratka CE, Xu J, Marin D, Treff NR, Duncan FE  The severity of meiotic aneuploidy is associated with altered morphokinetic variables of mouse oocyte maturation.  Hum Reprod Open  2024;2024(2):hoae023. pii:hoae023
  17. Gokyer D, Akinboro S, Zhou LT, Kleinhans A, Laronda MM, Duncan FE, Riley JK, Goldman KN, Babayev E  The oocyte microenvironment is altered in adolescents compared to oocyte donors.  bioRxiv  2024 Apr 06;. pii:2024.04.04.588118
  18. Salvi A, Li W, Dipali SS, Cologna SM, Pavone ME, Duncan FE, Burdette JE  Follicular fluid aids cell adhesion, spreading in an age independent manner and shows an age-dependent effect on DNA damage in fallopian tube epithelial cells.  Heliyon  2024 Mar 30;10(6):e27336. pii:e27336
  19. Boiani M, Duncan FE  A new initiative for 2024: increasing peer review transparency at MHR.  Mol Hum Reprod  2024 Mar 28;30(4). pii:gaae014
  20. Duncan FE, Boiani M  Influx of innovation: promoting the scientific advances of early career investigators in Molecular Human Reproduction.  Mol Hum Reprod  2024 Feb 29;30(3). pii:gaad050
  21. Converse A, Liu Z, Patel JC, Shakyawar S, Guda C, Bousfield GR, Kumar TR, Duncan FE  Oocyte quality is enhanced by hypoglycosylated FSH through increased cell-to-cell interaction during mouse follicle development.  Development  2023 Nov 15;150(22). pii:dev202170
  22. Dipali SS, Suebthawinkul C, Burdette JE, Pavone ME, Duncan FE  Human follicular fluid elicits select dose- and age-dependent effects on mouse oocytes and cumulus-oocyte complexes in a heterologous in vitro maturation assay.  Mol Hum Reprod  2023 Nov 01;29(11). pii:gaad039
  23. Babayev E, Suebthawinkul C, Gokyer D, Parkes WS, Rivas F, Pavone ME, Hall AR, Pritchard MT, Duncan FE  Cumulus expansion is impaired with advanced reproductive age due to loss of matrix integrity and reduced hyaluronan.  Aging Cell  2023 Nov;22(11):e14004. pii:e14004
  24. Dipali SS, King CD, Rose JP, Burdette JE, Campisi J, Schilling B, Duncan FE  Proteomic quantification of native and ECM-enriched mouse ovaries reveals an age-dependent fibro-inflammatory signature.  Aging (Albany NY)  2023 Oct 27;15(20):10821-10855. doi:10.18632/aging.205190
  25. Perrone R, Ashok Kumaar PV, Haky L, Hahn C, Riley R, Balough J, Zaza G, Soygur B, Hung K, Prado L  et al.  CD38 regulates ovarian function and fecundity via NAD+ metabolism.  iScience  2023 Oct 20;26(10):107949. pii:107949
  26. Amargant F, Zhou LT, Yuan Y, Nahar A, Krisher RL, Spate LD, Roberts RM, Prather RS, Rowell EE, Laronda MM  et al.  FGF2, LIF, and IGF1 (FLI) supplementation during human in vitro maturation enhances markers of gamete competence.  Hum Reprod  2023 Oct 03;38(10):1938-1951. doi:10.1093/humrep/dead162
  27. Zaniker EJ, Babayev E, Duncan FE  Common mechanisms of physiological and pathological rupture events in biology: novel insights into mammalian ovulation and beyond.  Biol Rev Camb Philos Soc  2023 Oct;98(5):1648-1667. doi:10.1111/brv.12970
  28. Boiani M, Duncan FE  'Human and Animal Model Reproductive Epigenetics' special collection: (un)intended marks on fertility.  Mol Hum Reprod  2023 Aug 30;29(9). pii:gaad032
  29. Gowett MQ, Perry SS, Aggarwal R, Zhou LT, Pavone ME, Duncan FE, Cheng WS  Associations of childhood allergies with parental reproductive and allergy history.  J Assist Reprod Genet  2023 Jun;40(6):1349-1359. doi:10.1007/s10815-023-02801-3
  30. Suebthawinkul C, Babayev E, Lee HC, Duncan FE  Morphokinetic parameters of mouse oocyte meiotic maturation and cumulus expansion are not affected by reproductive age or ploidy status.  J Assist Reprod Genet  2023 May;40(5):1197-1213. doi:10.1007/s10815-023-02779-y
  31. Zhang J, Goods BA, Pattarawat P, Wang Y, Haining T, Zhang Q, Shalek AK, Duncan FE, Woodruff TK, Xiao S  An ex vivo ovulation system enables the discovery of novel ovulatory pathways and nonhormonal contraceptive candidates†.  Biol Reprod  2023 Apr 11;108(4):629-644. doi:10.1093/biolre/ioad009
  32. O'Neill KE, Maher JY, Laronda MM, Duncan FE, LeDuc RD, Lujan ME, Oktay KH, Pouch AM, Segars JH, Tsui EL  et al.  Anatomic nomenclature and 3-dimensional regional model of the human ovary: call for a new paradigm.  Am J Obstet Gynecol  2023 Mar;228(3):270-275.e4. doi:10.1016/j.ajog.2022.09.040
  33. Cinzori ME, Pacyga DC, Babayev E, Duncan FE, Li Z, Williams PL, Flaws JA, Strakovsky RS  Ovarian volume partially explains associations of phthalate biomarkers with anti-Müllerian hormone and estradiol in midlife women.  Environ Int  2023 Feb;172:107771. doi:10.1016/j.envint.2023.107771
  34. Converse A, Zaniker EJ, Amargant F, Duncan FE  Recapitulating folliculogenesis and oogenesis outside the body: encapsulated in vitro follicle growth†.  Biol Reprod  2023 Jan 14;108(1):5-22. doi:10.1093/biolre/ioac176
  35. Chen YY, Chen S, Ok K, Duncan FE, O'Halloran TV, Woodruff TK  Zinc dynamics regulate early ovarian follicle development.  J Biol Chem  2023 Jan;299(1):102731. pii:102731
  36. Brieño-Enriquez MA, Duncan FE, Ghazi A, Klutstein M, Sebastiano V, Tyler J  Editorial: Germ cell development and reproductive aging.  Front Cell Dev Biol  2022;10:1051539. pii:1051539
  37. Suebthawinkul C, Babayev E, Zhou LT, Lee HC, Duncan FE  Quantitative morphokinetic parameters identify novel dynamics of oocyte meiotic maturation and cumulus expansion†.  Biol Reprod  2022 Oct 11;107(4):1097-1112. doi:10.1093/biolre/ioac139
  38. Babayev E, Xu M, Shea LD, Woodruff TK, Duncan FE  Follicle isolation methods reveal plasticity of granulosa cell steroidogenic capacity during mouse in vitro follicle growth.  Mol Hum Reprod  2022 Sep 29;28(10). pii:gaac033
  39. Ataman-Millhouse LM, Monahan P, Willingham R, Vigone G, Soulakis M, Gadea J, Jiménez-Movilla M, Romar R, Cánovas S, Woodruff TK  et al.  Broadening the educational pipeline: the global landscape of master of science programs in reproductive science and medicine.  Biol Reprod  2022 Sep 12;107(3):664-675. doi:10.1093/biolre/ioac113
  40. Ataman LM, Laronda MM, Gowett M, Trotter K, Anvari H, Fei F, Ingram A, Minette M, Suebthawinkul C, Taghvaei Z  et al.  Correction to: A synopsis of global frontiers in fertility preservation.  J Assist Reprod Genet  2022 Aug;39(8):1713-1714. doi:10.1007/s10815-022-02586-x
  41. Chen YY, Russo DD, Drake RS, Duncan FE, Shalek AK, Goods BA, Woodruff TK  Single-cell transcriptomics of staged oocytes and somatic cells reveal novel regulators of follicle activation.  Reproduction  2022 Aug 01;164(2):55-70. doi:10.1530/REP-22-0053
  42. Ataman LM, Laronda MM, Gowett M, Trotter K, Anvari H, Fei F, Ingram A, Minette M, Suebthawinkul C, Taghvaei Z  et al.  A synopsis of global frontiers in fertility preservation.  J Assist Reprod Genet  2022 Aug;39(8):1693-1712. doi:10.1007/s10815-022-02570-5
  43. Boiani M, Duncan FE,   A reproductive science perspective: deliberations on the stem cell guidelines update.  Mol Hum Reprod  2022 Apr 01;28(4). pii:gaac008
  44. Doherty CA, Amargant F, Shvartsman SY, Duncan FE, Gavis ER  Bidirectional communication in oogenesis: a dynamic conversation in mice and Drosophila.  Trends Cell Biol  2022 Apr;32(4):311-323. doi:10.1016/j.tcb.2021.11.005
  45. Babayev E, Duncan FE  Age-associated changes in cumulus cells and follicular fluid: the local oocyte microenvironment as a determinant of gamete quality.  Biol Reprod  2022 Feb 22;106(2):351-365. doi:10.1093/biolre/ioab241
  46. Duncan FE  Ex vivo recovery of mature eggs from unstimulated ovaries in pediatric fertility preservation: proceed with caution.  F S Rep  2021 Sep;2(3):267-268. doi:10.1016/j.xfre.2021.05.003
  47. Parkes WS, Amargant F, Zhou LT, Villanueva CE, Duncan FE, Pritchard MT  Hyaluronan and Collagen Are Prominent Extracellular Matrix Components in Bovine and Porcine Ovaries.  Genes (Basel)  2021 Jul 30;12(8). pii:1186
  48. Kusuhara A, Babayev E, Zhou LT, Singh VP, Gerton JL, Duncan FE  Immature Follicular Origins and Disrupted Oocyte Growth Pathways Contribute to Decreased Gamete Quality During Reproductive Juvenescence in Mice.  Front Cell Dev Biol  2021;9:693742. pii:693742
  49. Amargant F, Manuel SL, Larmore MJ, Johnson BW, Lawson M, Pritchard MT, Zelinski MB, Duncan FE  Sphingosine-1-phosphate and its mimetic FTY720 do not protect against radiation-induced ovarian fibrosis in the nonhuman primate†.  Biol Reprod  2021 May 07;104(5):1058-1070. doi:10.1093/biolre/ioab012
  50. Machlin JH, Barishansky SJ, Kelsh J, Larmore MJ, Johnson BW, Pritchard MT, Pavone ME, Duncan FE  Fibroinflammatory Signatures Increase with Age in the Human Ovary and Follicular Fluid.  Int J Mol Sci  2021 May 05;22(9). pii:4902

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