Northwestern University Feinberg School of Medicine

Mark Bevan Lab

About Our Lab

Our research focuses on the basal ganglia, a group of subcortical brain nuclei that are critical for voluntary movement, learning and motivation, and the primary site of dysfunction in psychomotor disorders such as Parkinson's disease, Huntington's disease, obsessive-compulsive disorder and addiction.

Selected Publications

Lahiri AK, Bevan MD.
Dopaminergic Transmission Rapidly and Persistently Enhances Excitability of D1 Receptor-Expressing Striatal Projection Neurons. 2020 Neuron 106:277-290

McIver EL, Atherton JF, Chu HY, Cosgrove KE, Kondapalli J, Wokosin D, Surmeier DJ, Bevan MD.
Maladaptive Downregulation of Autonomous Subthalamic Nucleus Activity Following the Loss of Midbrain Dopamine Neurons. 2019 Cell Reports 28:922-1002

Chu HY, McIver EL, Kovaleski RF, Atherton JF, Bevan MD.
Loss of Hyperdirect Pathway Cortico-Subthalamic Inputs Following Degeneration of Midbrain Dopamine Neurons.
2017 Neuron 95:1306-1318

Atherton JF, McIver EL, Mullen MRM, Wokosin DL, Surmeier DJBevan MD.
Early dysfunction and progressive degeneration of the subthalamic nucleus in mouse models of Huntington's disease.
2016 eLife 5:e21616

Chu HY, Atherton JF, Wokosin D, Surmeier DJ, Bevan MD.
Heterosynaptic regulation of external globus pallidus inputs to the subthalamic nucleus by the motor cortex.
2015 Neuron 85: 364–376

Mark Bevan, PhD

Mark Bevan, PhD
Professor in Physiology

For more information, click here to visit our department page.

Postdoctoral trainee and predoctoral technician positions in the Bevan lab, Department of Physiology, Northwestern University

Several postdoctoral research and predoctoral technician positions are available in the Bevan lab. The lab studies the neural mechanisms underlying basal ganglia-related psychomotor function and dysfunction in mouse models of Parkinson’s disease and Huntington’s disease. The lab uses a wide range of electrophysiological, optical, genetic, and behavioral interrogation approaches. Postdoctoral applicants should have a PhD in the life sciences, physics, or biomedical engineering, as well as research experience in neuroscience. An undergraduate degree in one of these fields is sufficient for the research technician position. Applications are particularly encouraged from highly motivated scientists with expertise and/or interest in electrophysiology, modern circuit interrogation approaches, and/or mouse behavior. Extensive training and mentorship will be provided. Salary is commensurate with experience and start date is negotiable. The positions will remain open until filled but early applications/expressions of interest are encouraged. Please submit a brief cover letter describing your career path and future goals, an NIH biosketch or CV, and contact information for 2-3 references to