News and Events
December 4, 2018
We are honored to receive RO1 NIH award which will fund studies optimizing CAR T cells’ anti-glioma activity via genetic engineering to enhance their persistence, targeting multiple tumor antigens, and improving their trafficking to
July 20, 2018
Congratulation to post-doctoral scholar Katarzyna Pituch,
Our research proposal was selected for the Lynn Sage Foundation Research Grant, 2018-19. This grant will support the work of
We are grateful to the Department of Radiology, Northwestern Medicine for a pilot imaging grant supporting the use of preclinical MRI facility. This grant will be used for investigating the application of whole brain radiation for enhancing delivery of imaging/therapeutic agents to brain metastases.
August 25, 2017
The Chicago Biomedical Consortium (CBC) announced Irina Balyasnikova (NU) received Catalyst Awards in Spring 2017 application round.
April 21, 2017
Congratulations to Katarzyna Pituch for being awarded a
December 14, 2016
Our proposal, Investigating CAR T cells for Glioblastoma Immunotherapy, has been selected for a Translational Bridge Award from the Robert H. Lurie Comprehensive Cancer Center of Northwestern University. The postdoctoral scholar, Katarzyna C. Pituch,
December 16, 2016
We are grateful to the Nora Redman Endowment Fund from the Community Foundation of Louisville for their generous gift, which will support work of postdoctoral scholar Michael I. Chastkofsky,
Dey M, Yu D, Kanojia D, Li G, Sukhanova M, Spencer DA, Pituch KC, Zhang L, Han Y, Ahmed AU, Aboody KS, Lesniak MS, Balyasnikova IV. Intranasal Oncolytic Virotherapy with CXCR4-Enhanced Stem Cells Extends Survival in Mouse Model of Glioma. Stem Cell Reports. 2016 Sep 13;7(3):471-82. doi: 10.1016/j.stemcr.2016.07.024. PMID:27594591
Cheng Y, Muroski ME, Petit DC, Mansell R, Vemulkar T, Morshed RA, Han Y, Balyasnikova IV, Horbinski CM, Huang X, Zhang L, Cowburn RP, Lesniak MS. Rotating magnetic field induced oscillation of magnetic particles for in vivo mechanical destruction of malignant glioma. J Control Release 223:75-84, 2016.
Cheng SH, Yu D, Tsai HM, Morshed RA, Kanojia D, Lo LW, Leoni L, Govind Y, Zhang L, Aboody KS, Lesniak MS, Chen CT, Balyasnikova IV. Dynamic In Vivo SPECT Imaging of Neural Stem Cells Functionalized with Radiolabeled Nanoparticles for Tracking of Glioblastoma. J Nucl Med 57(2):279-84, 2016.
Krenciute G, Krebs S, Torres D, Wu MF, Liu H, Dotti G, Li XN, Lesniak MS, Balyasnikova IV, Gottschalk S. Characterization and Functional Analysis of scFv-based Chimeric Antigen Receptors to Redirect T Cells to IL13Rα2-positive Glioma. Mol Ther 24(2):354-63, 2016.
Kim JW, Young JS, Solomaha E, Kanojia D, Lesniak MS, Balyasnikova IV. A novel single-chain antibody redirects adenovirus to IL13Rα2-expressing brain tumors. Sci Rep 5:18133, 2015.
Kanojia D, Balyasnikova IV, Morshed RA, Frank RT, Yu D, Zhang L, Spencer DA, Kim JW, Han Y, Yu D, Ahmed AU, Aboody KS, Lesniak MS. Neural Stem Cells Secreting Anti-HER2 Antibody Improve Survival in a Preclinical Model of HER2 Overexpressing Breast Cancer Brain Metastases. Stem Cells 33(10):2985-94, 2015.
Kim JW, Kane JR, Young JS, Chang AL, Kanojia D, Morshed RA, Miska J, Ahmed AU, Balyasnikova IV, Han Y, Zhang L, Curiel DT, Lesniak MS. A Genetically Modified Adenoviral Vector with a Phage Display-Derived Peptide Incorporated into Fiber Fibritin Chimera Prolongs Survival in Experimental Glioma. Hum Gene Ther 26(9):635-46, 2015.