Northwestern University Feinberg School of Medicine

Derek Walsh Lab

Our Lab

Research in our laboratory focuses on two aspects of DNA virus biology: 1) The role of the host translation system during infection by poxviruses. 2) Microtubule regulation and function during herpes simplex virus infection.

Selected Publications

Jha S, Rollins MG, Fuchs G, Procter DJ, Hall EA, Cozzolino K, Sarnow P, Savas JN, Walsh D  Trans-kingdom mimicry underlies ribosome customization by a poxvirus kinase.  Nature  2017. doi:10.1038/nature22814

Jovasevic V, Naghavi MH, Walsh D  Microtubule plus end-associated CLIP-170 initiates HSV-1 retrograde transport in primary human cells.  J Cell Biol  2015. PubMed:26504169

Malikov V, da Silva ES, Jovasevic V, Bennett G, de Souza Aranha Vieira DA, Schulte B, Diaz-Griffero F, Walsh D, Naghavi MH  HIV-1 capsids bind and exploit the kinesin-1 adaptor FEZ1 for inward movement to the nucleus.  Nat Commun 2015. PubMed:25818806

Walsh D, Mohr I  Coupling 40S ribosome recruitment to modification of a cap-binding initiation factor by eIF3 subunit e.  Genes Dev  2014. PubMed:24736843

Derek Walsh, PhD

Derek Walsh, PhD
Associate Professor in Microbiology-Immunology

For more information, click here to visit our department page.