Northwestern University Feinberg School of Medicine

Derek Walsh Lab

Our Lab

Research in our laboratory focuses on two aspects of DNA virus biology: 1) The role of the host translation system during infection by poxviruses. 2) Microtubule regulation and function during herpes simplex virus infection.

Selected Publications

DiGiuseppe S, Rollins MG, Bartom ET, Walsh D  ZNF598 Plays Distinct Roles in Interferon-Stimulated Gene Expression and Poxvirus Protein Synthesis.  Cell Rep  2018. pii:S2211-1247(18)30520-5

Procter DJ, Banerjee A, Nukui M, Kruse K, Gaponenko V, Murphy EA, Komarova Y, Walsh D  The HCMV Assembly Compartment Is a Dynamic Golgi-Derived MTOC that Controls Nuclear Rotation and Virus Spread.  Dev Cell  2018. pii:S1534-5807(18)30197-7

Jha S, Rollins MG, Fuchs G, Procter DJ, Hall EA, Cozzolino K, Sarnow P, Savas JN, Walsh D  Trans-kingdom mimicry underlies ribosome customization by a poxvirus kinase.  Nature  2017. doi:10.1038/nature22814

Chai Q, Jovasevic V, Malikov V, Sabo Y, Morham S, Walsh D, Naghavi MH  HIV-1 counteracts an innate restriction by amyloid precursor protein resulting in neurodegeneration.  Nat Commun  2017. doi:10.1038/s41467-017-01795-8

Derek Walsh, PhD

Derek Walsh, PhD
Associate Professor in Microbiology-Immunology

For more information, click here to visit our department page.