Northwestern University Feinberg School of Medicine

Mojgan Naghavi Lab

About Our Lab

Our lab aims to understand the molecular basis behind how microtubules, regulators of microtubule dynamics and microtubule motor proteins function to enable HIV-1 movement to and from the nucleus.

Recent Publications

Chai Q, Jovasevic V, Malikov V, Sabo Y, Morham S, Walsh D, Naghavi MH HIV-1 counteracts an innate restriction by amyloid precursor protein resulting in neurodegeneration. Nat Commun PMID: 29142315

Localized Phosphorylation of a Kinesin-1 Adaptor by a Capsid-Associated Kinase Regulates HIV-1 Motility and Uncoating. Malikov V, Naghavi MH  Localized Phosphorylation of a Kinesin-1 Adaptor by a Capsid-Associated Kinase Regulates HIV-1 Motility and Uncoating.  Cell Rep PubMed:28930676

Delaney MK, Malikov V, Chai Q, Zhao G, Naghavi MH  Distinct functions of diaphanous-related formins regulate HIV-1 uncoating and transport.  Proc Natl Acad Sci U S A  PubMed:28760985

Malikov V, da Silva ES, Jovasevic V, Bennett G, de Souza Aranha Vieira DA, Schulte B, Diaz-Griffero F, Walsh D, Naghavi MH  HIV-1 capsids bind and exploit the kinesin-1 adaptor FEZ1 for inward movement to the nucleus.  Nat Commun PubMed:25818806

Sabo Y, Walsh D, Barry DS, Tinaztepe S, de Los Santos K, Goff SP, Gundersen GG, Naghavi MH  HIV-1 induces the formation of stable microtubules to enhance early infection.  Cell Host Microbe     PubMed:24237699

More Publications

Mojgan Naghavi, PhD

Mojgan Naghavi, PhD
Associate Professor in Microbiology-Immunology

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