About Our Lab
Our research focuses on the basal ganglia, a group of subcortical brain nuclei that are critical for voluntary movement, learning and motivation, and the primary site of dysfunction in psychomotor disorders such as Parkinson's disease, Huntington's disease, obsessive-compulsive disorder and addiction.
Atherton JF, McIver EL, Mullen MRM, Wokosin DL, Surmeier DJ, Bevan MD.
Early dysfunction and progressive degeneration of the subthalamic nucleus in mouse models of Huntington's disease.
2016 eLife 5:e21616
Chu HY, Atherton JF, Wokosin D, Surmeier DJ, Bevan MD.
Heterosynaptic regulation of external globus pallidus inputs to the subthalamic nucleus by the motor cortex.
2015 Neuron 85: 364–376
Atherton JF, Menard A, Urbain N, Bevan MD.
Short-term depression of external globus pallidus-subthalamic nucleus synaptic transmission and implications for patterning subthalamic activity.
2013 J Neurosci 33: 7130–7144
Fan KY, Baufreton J, Surmeier DJ, Chan CS, Bevan MD.
Proliferation of external globus pallidus-subthalamic nucleus synapses following degeneration of midbrain dopamine neurons.
2012 J Neurosci 32: 13718–13728