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Northwestern University Feinberg School of Medicine
Theresa Walunas Lab

Publications

Learn more about the work that we do in the Walunas Laboratory through our recent publications. To view all related plublications, visit the faculty profile of Theresa Walunas, PhD.

 

  1. Carroll AJ, Robinson DG, Kane JM, Kordon A, Bannon J, Walunas TL, Brown CH  Multi-level barriers and facilitators to implementing evidence-based antipsychotics in the treatment of early-phase schizophrenia.  Front Health Serv  2024;4:1385398. pii:1385398
  2. Adekkanattu P, Furmanchuk A, Wu Y, Pathak A, Patra BG, Bost S, Morrow D, Wang GH, Yang Y, Forrest NJ  et al.  Deep learning for identifying personal and family history of suicidal thoughts and behaviors from EHRs.  NPJ Digit Med  2024 Sep 28;7(1):260. pii:260
  3. Ye J, Orji IA, Birkett MA, Hirschhorn LR, Walunas TL, Smith JD, Kandula NR, Shedul GL, Huffman MD, Ojji DB  Community-Based Participatory Research and System Dynamics Modeling for Improving Retention in Hypertension Care.  JAMA Netw Open  2024 Aug 01;7(8):e2430213. pii:e2430213
  4. Rabin EE, Huang J, Kim M, Mozny A, Lauing KL, Penco-Campillo M, Zhai L, Bommi P, Mi X, Power EA  et al.  Age-stratified comorbid and pharmacologic analysis of patients with glioblastoma.  Brain Behav Immun Health  2024 Jul;38:100753. pii:100753
  5. Smith JD, Carroll AJ, Sanuade OA, Johnson R, Abramsohn EM, Abbas H, Ahmad FS, Eggleston A, Lazar D, Lindau ST  et al.  Process of Engaging Community and Scientific Partners in the Development of the CIRCL-Chicago Study Protocol.  Ethn Dis  2023 Dec;DECIPHeR(Spec Issue):18-26. doi:10.18865/ed.DECIPHeR.18
  6. Mosley JD, Shelley JP, Dickson AL, Zanussi J, Daniel LL, Zheng NS, Bastarache L, Wei WQ, Shi M, Jarvik GP  et al.  Clinical associations with a polygenic predisposition to benign lower white blood cell counts.  Nat Commun  2024 Apr 22;15(1):3384. pii:3384
  7. Hui D, Dudek S, Kiryluk K, Walunas TL, Kullo IJ, Wei WQ, Tiwari HK, Peterson JF, Chung WK, Davis B  et al.  Risk factors affecting polygenic score performance across diverse cohorts.  medRxiv  2024 Apr 10;. pii:2023.05.10.23289777
  8. Tran SD, Lin J, Galvez C, Rasmussen LV, Pacheco J, Perottino GM, Rahbari KJ, Miller CD, John JD, Theros J  et al.  Rapid identification of inflammatory arthritis and associated adverse events following immune checkpoint therapy: a machine learning approach.  Front Immunol  2024;15:1331959. pii:1331959
  9. Adekkanattu P, Furmanchuk A, Wu Y, Pathak A, Patra BG, Bost S, Morrow D, Wang GH, Yang Y, Forrest NJ  et al.  Detection of Personal and Family History of Suicidal Thoughts and Behaviors using Deep Learning and Natural Language Processing: A Multi-Site Study.  Res Sq  2024 Mar 11;. pii:rs.3.rs-4014472
  10. Ye J, Sanuade OA, Hirschhorn LR, Walunas TL, Smith JD, Birkett MA, Baldridge AS, Ojji DB, Huffman MD  Interventions and contextual factors to improve retention in care for patients with hypertension in primary care: Hermeneutic systematic review.  Prev Med  2024 Mar;180:107880. doi:10.1016/j.ypmed.2024.107880
  11. Lennon NJ, Kottyan LC, Kachulis C, Abul-Husn NS, Arias J, Belbin G, Below JE, Berndt SI, Chung WK, Cimino JJ  et al.  Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations.  Nat Med  2024 Feb;30(2):480-487. doi:10.1038/s41591-024-02796-z
  12. Johnson M, Bell A, Lauing KL, Ladomersky E, Zhai L, Penco-Campillo M, Shah Y, Mauer E, Xiu J, Nicolaides T  et al.  Advanced Age in Humans and Mouse Models of Glioblastoma Show Decreased Survival from Extratumoral Influence.  Clin Cancer Res  2023 Dec 01;29(23):4973-4989. doi:10.1158/1078-0432.CCR-23-0834
  13. Forrest N, Jackson KL, Tran S, Pacheco JA, Mitrovic V, Furmanchuk A, Kho AN, Ramsey-Goldman R, Walunas TL  Identification and assessment of classification criteria attributes for systemic lupus erythematosus in a regional medical record data network.  Lupus Sci Med  2023 Oct;10(2). pii:e000963
  14. Krefman AE, Ciolino JD, Kan AK, Maki B, McHugh M, Smith JD, Bannon J, Carroll AJ, Bustamante P, Frye C  et al.  Rationale and design for Healthy Hearts for Michigan (HH4M): A pragmatic single-arm hybrid effectiveness-implementation study.  Contemp Clin Trials Commun  2023 Oct;35:101199. pii:101199
  15. McHugh M, Heinrich J, Philbin S, Bishop D, Smith JD, Knapke JM, Day A, Walunas TL  Declining Participation in Primary Care Quality Improvement Research: A Qualitative Study.  Ann Fam Med  2023;21(5):388-394. doi:10.1370/afm.3007
  16. Mosley JD, Shelley JP, Dickson AL, Zanussi J, Daniel LL, Zheng NS, Bastarache L, Wei WQ, Shi M, Jarvik GP  et al.  Clinical consequences of a polygenic predisposition to benign lower white blood cell counts: Consequences of benign WBC count genetics.  medRxiv  2023 Aug 21;. pii:2023.08.20.23294331
  17. Brandt PS, Kho A, Luo Y, Pacheco JA, Walunas TL, Hakonarson H, Hripcsak G, Liu C, Shang N, Weng C  et al.  Characterizing variability of electronic health record-driven phenotype definitions.  J Am Med Inform Assoc  2023 Feb 16;30(3):427-437. doi:10.1093/jamia/ocac235
  18. Liu L, Khan A, Sanchez-Rodriguez E, Zanoni F, Li Y, Steers N, Balderes O, Zhang J, Krithivasan P, LeDesma RA  et al.  Author Correction: Genetic regulation of serum IgA levels and susceptibility to common immune, infectious, kidney, and cardio-metabolic traits.  Nat Commun  2023 Feb 06;14(1):655. pii:655
  19. Pacheco JA, Rasmussen LV, Wiley K, Person TN, Cronkite DJ, Sohn S, Murphy S, Gundelach JH, Gainer V, Castro VM  et al.  Evaluation of the portability of computable phenotypes with natural language processing in the eMERGE network.  Sci Rep  2023 Feb 03;13(1):1971. pii:1971
  20. Liu L, Khan A, Sanchez-Rodriguez E, Zanoni F, Li Y, Steers N, Balderes O, Zhang J, Krithivasan P, LeDesma RA  et al.  Genetic regulation of serum IgA levels and susceptibility to common immune, infectious, kidney, and cardio-metabolic traits.  Nat Commun  2022 Nov 11;13(1):6859. pii:6859
  21. Namjou B, Lape M, Malolepsza E, DeVore SB, Weirauch MT, Dikilitas O, Jarvik GP, Kiryluk K, Kullo IJ, Liu C  et al.  Multiancestral polygenic risk score for pediatric asthma.  J Allergy Clin Immunol  2022 Nov;150(5):1086-1096. doi:10.1016/j.jaci.2022.03.035
  22. Ko D, Forrest N, Mai Q, Pawlowski A, Balsley K, Chung A, Ramsey-Goldman R, Walunas TL  Electronic health record data use in the assessment of quality indicators for glucocorticoid osteoporosis screening in systemic lupus erythematosus.  Lupus  2022 Oct;31(12):1516-1522. doi:10.1177/09612033221116726
  23. Huang S, Lewis MO, Bao Y, Adekkanattu P, Adkins LE, Banerjee S, Bian J, Gellad WF, Goodin AJ, Luo Y  et al.  Predictive Modeling for Suicide-Related Outcomes and Risk Factors among Patients with Pain Conditions: A Systematic Review.  J Clin Med  2022 Aug 17;11(16). pii:4813
  24. Nguyen AM, Cleland CM, Dickinson LM, Barry MP, Cykert S, Duffy FD, Kuzel AJ, Lindner SR, Parchman ML, Shelley DR  et al.  Considerations Before Selecting a Stepped-Wedge Cluster Randomized Trial Design for a Practice Improvement Study.  Ann Fam Med  2022;20(3):255-261. doi:10.1370/afm.2810
  25. Rabin EE, Kim M, Mozny A, Cardoza K, Bell AC, Zhai L, Bommi P, Lauing KL, King AL, Armstrong TS  et al.  A systematic review of pharmacologic treatment efficacy for depression in older patients with cancer.  Brain Behav Immun Health  2022 May;21:100449. pii:100449
  26. Dusetzina SB, Huskamp HA, Rothman RL, Pinheiro LC, Roberts AW, Shah ND, Walunas TL, Wood WA, Zuckerman AD, Zullig LL  et al.  Many Medicare Beneficiaries Do Not Fill High-Price Specialty Drug Prescriptions.  Health Aff (Millwood)  2022 Apr;41(4):487-496. doi:10.1377/hlthaff.2021.01742
  27. Olender SA, Perez KK, Go AS, Balani B, Price-Haywood EG, Shah NS, Wang S, Walunas TL, Swaminathan S, Slim J  et al.  Remdesivir for Severe Coronavirus Disease 2019 (COVID-19) Versus a Cohort Receiving Standard of Care.  Clin Infect Dis  2021 Dec 06;73(11):e4166-e4174. doi:10.1093/cid/ciaa1041
  28. Bayless NL, Bluestone JA, Bucktrout S, Butterfield LH, Jaffee EM, Koch CA, Roep BO, Sharpe AH, Murphy WJ, Villani AC  et al.  Development of preclinical and clinical models for immune-related adverse events following checkpoint immunotherapy: a perspective from SITC and AACR.  J Immunother Cancer  2021 Sep;9(9). pii:e002627
  29. Olender SA, Walunas TL, Martinez E, Perez KK, Castagna A, Wang S, Kurbegov D, Goyal P, Ripamonti D, Balani B  et al.  Remdesivir Versus Standard-of-Care for Severe Coronavirus Disease 2019 Infection: An Analysis of 28-Day Mortality.  Open Forum Infect Dis  2021 Jul;8(7):ofab278. pii:ofab278
  30. Kawai VK, Shi M, Liu G, Feng Q, Wei W, Chung CP, Walunas TL, Gordon AS, Linneman JG, Hebbring SJ  et al.  Pleiotropy of systemic lupus erythematosus risk alleles and cardiometabolic disorders: A phenome-wide association study and inverse-variance weighted meta-analysis.  Lupus  2021 Jul;30(8):1264-1272. doi:10.1177/09612033211014952
  31. Walunas TL, Ghosh AS, Pacheco JA, Mitrovic V, Wu A, Jackson KL, Schusler R, Chung A, Erickson D, Mancera-Cuevas K  et al.  Evaluation of structured data from electronic health records to identify clinical classification criteria attributes for systemic lupus erythematosus.  Lupus Sci Med  2021 Apr;8(1). pii:e000488
  32. Walunas TL, Ye J, Bannon J, Wang A, Kho AN, Smith JD, Soulakis N  Does coaching matter? Examining the impact of specific practice facilitation strategies on implementation of quality improvement interventions in the Healthy Hearts in the Heartland study.  Implement Sci  2021 Mar 31;16(1):33. pii:33
  33. Solberg LI, Kuzel A, Parchman ML, Shelley DR, Dickinson WP, Walunas TL, Nguyen AM, Fagnan LJ, Cykert S, Cohen DJ  et al.  A Taxonomy for External Support for Practice Transformation.  J Am Board Fam Med  2021;34(1):32-39. doi:10.3122/jabfm.2021.01.200225
  34. Ye J, Zhang R, Bannon JE, Wang AA, Walunas TL, Kho AN, Soulakis ND  Identifying Practice Facilitation Delays and Barriers in Primary Care Quality Improvement.  J Am Board Fam Med  2020;33(5):655-664. doi:10.3122/jabfm.2020.05.200058
  35. Joo YY, Actkins K, Pacheco JA, Basile AO, Carroll R, Crosslin DR, Day F, Denny JC, Velez Edwards DR, Hakonarson H  et al.  A Polygenic and Phenotypic Risk Prediction for Polycystic Ovary Syndrome Evaluated by Phenome-Wide Association Studies.  J Clin Endocrinol Metab  2020 Jun 01;105(6):1918-36. pii:dgz326
  36. Persell SD, Liss DT, Walunas TL, Ciolino JD, Ahmad FS, Brown T, French DD, Hountz R, Iversen K, Lindau ST  et al.  Effects of 2 Forms of Practice Facilitation on Cardiovascular Prevention in Primary Care: A Practice-randomized, Comparative Effectiveness Trial.  Med Care  2020 Apr;58(4):344-351. doi:10.1097/MLR.0000000000001260
  37. Ahmad FS, Rasmussen LV, Persell SD, Richardson JE, Liss DT, Kenly P, Chung I, French DD, Walunas TL, Schriever A  et al.  Challenges to electronic clinical quality measurement using third-party platforms in primary care practices: the healthy hearts in the heartland experience.  JAMIA Open  2019 Dec;2(4):423-428. doi:10.1093/jamiaopen/ooz038
  38. McHugh M, Brown T, Liss DT, Persell SD, Garrett M, Walunas TL  Qualitative evaluation of a cardiovascular quality improvement programmereveals sizable data inaccuracies in small primary care practices.  BMJ Open Qual  2019;8(4):e000702. pii:e000702
  39. Shang N, Liu C, Rasmussen LV, Ta CN, Caroll RJ, Benoit B, Lingren T, Dikilitas O, Mentch FD, Carrell DS  et al.  Making work visible for electronic phenotype implementation: Lessons learned from the eMERGE network.  J Biomed Inform  2019 Nov;99:103293. doi:10.1016/j.jbi.2019.103293
  40. Walunas TL, Ghosh AS, Pacheco JA, Jackson KL, Chung AH, Erickson DL, Mancera-Cuevas K, Ramsey-Goldman R, Kho AN  Assessing the Concordance of Clinical Classification Criteria for Lupus Between Electronic Health Records and a Physician Curated Registry.  Stud Health Technol Inform  2019 Aug 21;264:1466-1467. doi:10.3233/SHTI190487
  41. Ciolino JD, Jackson KL, Liss DT, Brown T, Walunas TL, Murakami L, Chung I, Persell SD, Kho AN  Design of healthy hearts in the heartland (H3): A practice-randomized, comparative effectiveness study.  Contemp Clin Trials  2018 Aug;71:47-54. doi:10.1016/j.cct.2018.06.004
  42. Fagnan LJ, Walunas TL, Parchman ML, Dickinson CL, Murphy KM, Howell R, Jackson KL, Madden MB, Ciesla JR, Mazurek KD  et al.  Engaging Primary Care Practices in Studies of Improvement: Did You Budget Enough for Practice Recruitment?  Ann Fam Med  2018 Apr;16(Suppl 1):S72-S79. doi:10.1370/afm.2199
  43. McHugh M, Brown T, Liss DT, Walunas TL, Persell SD  Practice Facilitators' and Leaders' Perspectives on a Facilitated Quality Improvement Program.  Ann Fam Med  2018 Apr;16(Suppl 1):S65-S71. doi:10.1370/afm.2197
  44. Walunas TL, Jackson KL, Chung AH, Mancera-Cuevas KA, Erickson DL, Ramsey-Goldman R, Kho A  Disease Outcomes and Care Fragmentation Among Patients With Systemic Lupus Erythematosus.  Arthritis Care Res (Hoboken)  2017 Sep;69(9):1369-1376. doi:10.1002/acr.23161
  45. French DD, Behrens JJ, Jackson KL, Kho AN, Walunas TL, Evans CT, Mbagwu M, Margo CE, Bryar PJ  Payment Reform Needed to Address Health Disparities of Undiagnosed Diabetic Retinopathy in the City of Chicago.  Ophthalmol Ther  2017 Jun;6(1):123-131. doi:10.1007/s40123-016-0072-4
  46. Kho AN, Cashy JP, Jackson KL, Pah AR, Goel S, Boehnke J, Humphries JE, Kominers SD, Hota BN, Sims SA  et al.  Design and implementation of a privacy preserving electronic health record linkage tool in Chicago.  J Am Med Inform Assoc  2015 Sep;22(5):1072-80. doi:10.1093/jamia/ocv038