Interdisciplinary approaches to studying mechanisms of lung injury.

The Sznajder Lab

Our Research

Our laboratory utilizes interdisciplinary approaches to study mechanisms of lung injury. We focus on the role played by LUBAC and Na,K-ATPase during influenza A pneumonitis. Another focus is on the sensing and effects of hypercapnia in the lungs leading to lung and muscle dysfunction. We also study lung injury and proteostasis, which encompasses cellular processes that regulate protein folding, misfolding, unfolding, degradation, and repair.

Explore Our Research

Lab Leadership

Jacob I. Sznajder, MD
Ernest S. Bazley Professor of Asthma and Related Disorders
Professor of Medicine (Pulmonary and Critical Care) and Cell & Developmental Biology

Collaborators

Feinberg Collaborators

Ankit Bharat, MBBS, Chief of Thoracic Surgery in the Department of Surgery, Harold L. and Margaret N. Method Professor of Surgery, and Professor of Surgery (Thoracic Surgery) and Medicine (Pulmonary and Critical Care)
G.R. Scott Budinger, MD, Chief of Pulmonary and Critical Care in the Department of Medicine, Ernest S. Bazley Professor of Airway Diseases, and Professor of Medicine (Pulmonary and Critical Care) and Cell & Developmental Biology
Navdeep S. Chandel, PhD, David W. Cugell, MD, Professor and Professor of Medicine (Pulmonary and Critical Care) and Biochemistry & Molecular Genetics
Cara J. Gottardi, PhD, Associate Professor of Medicine (Pulmonary and Critical Care) and Cell & Developmental Biology
Alexander Misharin, MD, PhD, Associate Professor of Medicine (Pulmonary and Critical Care)
Karen M. Ridge, PhD, Ernest S. Bazley Professor of Pulmonary Sciences and Professor of Medicine (Pulmonary and Critical Care) and Cell and Developmental Biology

External Collaborators

Aaron Ciechanover, MD, DSc, Technion-Israel Institute of Technology
Susanne Herold, MD, PhD, Justus-Liebig Universitat Giessen
Esther Barreiro, MD, Institut Hospital del Mar d'Investigacions Mediques
Eoin Cummins, PhD, University College Dublin Conway Institute of Biomolecular and Biomedical Research
Yosef Gruenbaum, PhD, The Hebrew University of Jerusalem
Cormac Taylor, PhD, University College Dublin Conway Institute of Biomolecular and Biomedical Research
Istvan Vadasz, MD, Justus-Liebig Universitat Giessen
Olga Vagin, PhD, University of California, Los Angeles