Skip to main content
Northwestern University Feinberg School of Medicine
Implementation Intelligence Laboratory

Publications

Learn more about the work that we do in the Intelligence Implementation Laboratory through our publications.

Highlighted Publications:

  1. Ahmad FS, Khan SS, Levin MG  Implementation Intelligence With AI-Prospective Evaluations Needed.  JAMA Cardiol  2025 Nov 10;. doi:10.1001/jamacardio.2025.4668
  2. Hourmozdi J, Easton N, Benigeri S, Thomas JD, Narang A, Ouyang D, Duffy G, Upton R, Hawkes W, Akerman A  et al.  Evaluating the Performance and Potential Bias of Predictive Models for Detection of Transthyretin Cardiac Amyloidosis.  JACC Adv  2025 Aug;4(8):101901. pii:101901
  3. Philbin SE, Gleason LP, Persell SD, Walter E, Petito LC, Tibrewala A, Yancy CW, Beidas RS, Wilcox JE, Mutharasan RK  et al.  Barriers and Facilitators to Heart Failure Guideline-Directed Medical Therapy in an Integrated Health System and Federally Qualified Health Centers: A Thematic Qualitative Analysis.  J Gen Intern Med  2025 May 05;. doi:10.1007/s11606-025-09515-5
  4. Ahmad FS, Hu TL, Adler ED, Petito LC, Wehbe RM, Wilcox JE, Mutharasan RK, Nardone B, Tadel M, Greenberg B  et al.  Performance of risk models to predict mortality risk for patients with heart failure: evaluation in an integrated health system.  Clin Res Cardiol  2024 Sep;113(9):1343-1354. doi:10.1007/s00392-024-02433-2
  5. Cheema B, Mutharasan RK, Sharma A, Jacobs M, Powers K, Lehrer S, Wehbe FH, Ronald J, Pifer L, Rich JD  et al.  Augmented Intelligence to Identify Patients With Advanced Heart Failure in an Integrated Health System.  JACC Adv  2022 Oct;1(4). pii:100123
  6. Ahmad FS, Jackson KL, Yount SE, Rothrock NE, Kallen MA, Lacson L, Bilimoria KY, Kho AN, Mutharasan RK, McCullough PA  et al.  The development and initial validation of the PROMIS®+HF-27 and PROMIS+HF-10 profiles.  ESC Heart Fail  2022 Oct;9(5):3380-3392. doi:10.1002/ehf2.14061
  7. Shah KP, Khan SS, Baldridge AS, Grady KL, Cella D, Goyal P, Allen LA, Smith JD, Lagu TC, Ahmad FS  Health Status in Heart Failure and Cancer: Analysis of the Medicare Health Outcomes Survey 2016-2020.  JACC Heart Fail  2024 Jul;12(7):1166-1178. doi:10.1016/j.jchf.2023.10.003

 

Most Recent Publications:

  1. Zelicha H, Weitzner ZN, Park S, Babb TG, Bernhardt V, Ahmad FS, Cella D, Chen Y, Livingston EH  Improvement in breathlessness following bariatric surgery as measured by a new heart failure-specific health-related quality of life instrument: a prospective longitudinal study.  Surg Obes Relat Dis  2026 Jan;22(1):137-144. doi:10.1016/j.soard.2025.09.014
  2. Ahmad FS, Wehbe RM, Wilcox JE  The SCAI Is Not the Limit: Refining Dynamic Shock Trajectories With Machine Learning-Based Phenotyping.  JACC Heart Fail  2025 Dec;13(12):102700. doi:10.1016/j.jchf.2025.102700
  3. Alexander TJ, Gauen AM, Petito LC, Kohli-Lynch CN, Carton TW, Smith SM, Merritt G, Ahmad FS, Allen NB  Hypertension in Young Adults: Social Determinants of Prevalence, Awareness, Treatment, and Control.  Am J Hypertens  2025 Nov 13;. pii:hpaf203
  4. Angus DC, Khera R, Lieu T, Liu V, Ahmad FS, Anderson B, Bhavani SV, Bindman A, Brennan T, Celi LA  et al.  AI, Health, and Health Care Today and Tomorrow: The JAMA Summit Report on Artificial Intelligence.  JAMA  2025 Nov 11;334(18):1650-1664. doi:10.1001/jama.2025.18490
  5. Ahmad FS, Khan SS, Levin MG  Implementation Intelligence With AI-Prospective Evaluations Needed.  JAMA Cardiol  2025 Nov 10;. doi:10.1001/jamacardio.2025.4668
  6. Desai AS, Pandey A, Suratekar R, Ahmad FS, Alger HM, Anto AG, Nujum G S, Lopez-Jimenez F, Oh JK, Asfahan S  et al.  Predicting Heart Failure From 12-Lead ECGs Using AI: A HeartShare/AMP-HF Pooled Cohort Analysis.  J Am Coll Cardiol  2025 Nov 08;. pii:S0735-1097(25)10079-X
  7. Biswas D, Thangaraj P, Pedroso AF, Ogunniyi MO, Maddox TM, Ahmad FS, Khera R  Artificial Intelligence for Cardiovascular Care in Action: From Learning to Implementation in Health Systems.  JACC Adv  2025 Nov;4(11 Pt 2):102307. pii:102307
  8. Mizuno A, Ahmad FS, Brahmbhatt DH  Behavioral Intelligence in Action: Implementation Science and Cardiovascular Learning Health Systems.  JACC Adv  2025 Nov;4(11 Pt 2):102351. pii:102351
  9. Duffy G, Oikonomou EK, Easton N, Usuku H, Patel J, Katsumata Y, Yamasawa D, Stern L, Goto S, Tsujita K  et al.  International Validation of Echocardiographic Artificial Intelligence Amyloid Detection Algorithm.  JACC Adv  2025 Nov;4(11 Pt 2):102067. pii:102067
  10. Maznyczka A, Nuis RJ, Shiri I, Ternacle J, Garot P, van den Dorpel MMP, Khokhar AA, De Lucia R, Orini M, Kutty S  et al.  Artificial Intelligence in Valvular Heart Disease: Innovations and Future Directions.  JACC Cardiovasc Interv  2025 Oct 27;18(20):2439-2457. doi:10.1016/j.jcin.2025.08.031
  11. Khan SS, Harrington RA, Ahmad FS  Blood Pressure Measurement in Retail Stores and Population Health.  JAMA Cardiol  2025 Oct 01;10(10):1049. doi:10.1001/jamacardio.2025.2492
  12. Huang X, Hughes Z, Fonarow GC, Ahmad FS, Shah NS, Chuzi S, Kershaw KN, Greenland P, Khan SS, Petito LC  Racial and Ethnic Differences in Patient Age at First Hospitalization for Heart Failure.  J Am Coll Cardiol  2025 Sep 09;86(10):711-720. doi:10.1016/j.jacc.2025.06.046
  13. Hourmozdi J, Easton N, Benigeri S, Thomas JD, Narang A, Ouyang D, Duffy G, Upton R, Hawkes W, Akerman A  et al.  Evaluating the Performance and Potential Bias of Predictive Models for Detection of Transthyretin Cardiac Amyloidosis.  JACC Adv  2025 Aug;4(8):101901. pii:101901
  14. Rambarat P, DeVore AD, Bhatt AS, Allen LA, McIlvennan CK, Cotter G, Mukhopadhyay A, Ahmad T, Ahmad FS, Psotka MA  Failure to Launch: Insights From Randomized Trials on Implementation Strategies for Guideline-Directed Therapies for Heart Failure.  JACC Heart Fail  2025 Jun;13(6):887-900. doi:10.1016/j.jchf.2025.02.023
  15. Armoundas AA, Ahmad FS, Attia ZI, Doudesis D, Khera R, Kyriakoulis KG, Stergiou GS, Tang WHW  Controversy in Hypertension: Pro-Side of the Argument Using Artificial Intelligence for Hypertension Diagnosis and Management.  Hypertension  2025 Jun;82(6):929-944. doi:10.1161/HYPERTENSIONAHA.124.22349
  16. Smith JD, Carroll AJ, Tedla YG, Sanuade OA, Merle JL, Heinrich J, Bannon J, Abramsohn EM, Ahmad FS, Lazar D  et al.  Community intervention to reduce cardiovascular disease in Chicago (CIRCL-Chicago): protocol for a type 3 hybrid effectiveness-implementation study using a parallel cluster-randomized trial design.  Implement Sci  2025 May 05;20(1):19. pii:19
  17. Philbin SE, Gleason LP, Persell SD, Walter E, Petito LC, Tibrewala A, Yancy CW, Beidas RS, Wilcox JE, Mutharasan RK  et al.  Barriers and Facilitators to Heart Failure Guideline-Directed Medical Therapy in an Integrated Health System and Federally Qualified Health Centers: A Thematic Qualitative Analysis.  J Gen Intern Med  2025 May 05;. doi:10.1007/s11606-025-09515-5
  18. Nargesi AA, Adejumo P, Dhingra LS, Rosand B, Hengartner A, Coppi A, Benigeri S, Sen S, Ahmad T, Nadkarni GN  et al.  Automated Identification of Heart Failure With Reduced Ejection Fraction Using Deep Learning-Based Natural Language Processing.  JACC Heart Fail  2025 Jan;13(1):75-87. doi:10.1016/j.jchf.2024.08.012
  19. Shimbo D, Shah RU, Abdalla M, Agarwal R, Ahmad FS, Anaya G, Attia ZI, Bull S, Chang AR, Commodore-Mensah Y  et al.  Transforming Hypertension Diagnosis and Management in The Era of Artificial Intelligence: A 2023 National Heart, Lung, and Blood Institute (NHLBI) Workshop Report.  Hypertension  2025 Jan;82(1):36-45. doi:10.1161/HYPERTENSIONAHA.124.22095
  20. Duffy G, Oikonomou E, Hourmozdi J, Usuku H, Patel J, Stern L, Goto S, Tsujita K, Khera R, Ahmad FS  et al.  International Validation of Echocardiographic AI Amyloid Detection Algorithm.  medRxiv  2024 Dec 16;. pii:2024.12.14.24319049
  21. Ahmad FS, Hu TL, Adler ED, Petito LC, Wehbe RM, Wilcox JE, Mutharasan RK, Nardone B, Tadel M, Greenberg B  et al.  Performance of risk models to predict mortality risk for patients with heart failure: evaluation in an integrated health system.  Clin Res Cardiol  2024 Sep;113(9):1343-1354. doi:10.1007/s00392-024-02433-2
  22. Luo Y, Mao C, Sanchez-Pinto LN, Ahmad FS, Naidech A, Rasmussen L, Pacheco JA, Schneider D, Mithal LB, Dresden S  et al.  Northwestern University resource and education development initiatives to advance collaborative artificial intelligence across the learning health system.  Learn Health Syst  2024 Jul;8(3):e10417. pii:e10417
  23. Shah KP, Khan SS, Baldridge AS, Grady KL, Cella D, Goyal P, Allen LA, Smith JD, Lagu TC, Ahmad FS  Health Status in Heart Failure and Cancer: Analysis of the Medicare Health Outcomes Survey 2016-2020.  JACC Heart Fail  2024 Jul;12(7):1166-1178. doi:10.1016/j.jchf.2023.10.003
  24. Edmonston D, Lydon E, Mulder H, Chiswell K, Lampron Z, Marsolo K, Goss A, Ayoub I, Shah RC, Chang AR  et al.  Concordance With Screening and Treatment Guidelines for Chronic Kidney Disease in Type 2 Diabetes.  JAMA Netw Open  2024 Jun 03;7(6):e2418808. pii:e2418808
  25. Smith JD, Carroll AJ, Sanuade OA, Johnson R, Abramsohn EM, Abbas H, Ahmad FS, Eggleston A, Lazar D, Lindau ST  et al.  Process of Engaging Community and Scientific Partners in the Development of the CIRCL-Chicago Study Protocol.  Ethn Dis  2023 Dec;DECIPHeR(Spec Issue):18-26. doi:10.18865/ed.DECIPHeR.18
  26. Santos CAQ, Tseng M, Martinez AI, Shankaran S, Hodgson HA, Ahmad FS, Zhang H, Sievert DM, Trick WE  Comparative antimicrobial use in coronavirus disease 2019 (COVID-19) and non-COVID-19 inpatients from 2019 to 2020: A multicenter ecological study.  Infect Control Hosp Epidemiol  2024 Mar;45(3):335-342. doi:10.1017/ice.2023.180
  27. Narcisse DI, Kim H, Wruck LM, Stebbins AL, Muñoz D, Kripalani S, Effron MB, Gupta K, Anderson RD, Jain SK  et al.  Comparative Effectiveness of Aspirin Dosing in Cardiovascular Disease and Diabetes Mellitus: A Subgroup Analysis of the ADAPTABLE Trial.  Diabetes Care  2024 Jan 01;47(1):81-88. doi:10.2337/dc23-0749
  28. Salerno C, Pack QR, Jurkowski B, McAnally K, Dejong C, Ahmad FS, Lagu T  "I Just Wanted Nothing More Than to Get in a Real Shower": Patient Experience of the Inpatient Wait for a Heart Transplant.  J Card Fail  2023 Dec;29(12):1672-1677. doi:10.1016/j.cardfail.2023.05.020
  29. Wehbe RM, Katsaggelos AK, Hammond KJ, Hong H, Ahmad FS, Ouyang D, Shah SJ, McCarthy PM, Thomas JD  Deep Learning for Cardiovascular Imaging: A Review.  JAMA Cardiol  2023 Nov 01;8(11):1089-1098. doi:10.1001/jamacardio.2023.3142
  30. Swat SA, Helmkamp LJ, Tietbohl C, Thompson JS, Fitzgerald M, McIlvennan CK, Harger G, Ho PM, Ahmad FS, Ahmad T  et al.  Clinical Inertia Among Outpatients With Heart Failure: Application of Treatment Nonintensification Taxonomy to EPIC-HF Trial.  JACC Heart Fail  2023 Nov;11(11):1579-1591. doi:10.1016/j.jchf.2023.06.022
  31. Girotra S, Stebbins A, Wruck L, Marquis-Gravel G, Gupta K, Farrehi P, Benziger CP, Effron MB, Whittle J, Muñoz D  et al.  Aspirin Dosing for Secondary Prevention of Atherosclerotic Cardiovascular Disease in Patients Treated With P2Y12 Inhibitors.  J Am Heart Assoc  2023 Oct 17;12(20):e030385. pii:e030385
  32. Hosseini M, Gao CA, Liebovitz DM, Carvalho AM, Ahmad FS, Luo Y, MacDonald N, Holmes KL, Kho A  An exploratory survey about using ChatGPT in education, healthcare, and research.  PLoS One  2023;18(10):e0292216. pii:e0292216
  33. Franklin D, Tzavelis A, Lee JY, Chung HU, Trueb J, Arafa H, Kwak SS, Huang I, Liu Y, Rathod M  et al.  Synchronized wearables for the detection of haemodynamic states via electrocardiography and multispectral photoplethysmography.  Nat Biomed Eng  2023 Oct;7(10):1229-1241. doi:10.1038/s41551-023-01098-y
  34. Nargesi AA, Adejumo P, Dhingra L, Rosand B, Hengartner A, Coppi A, Benigeri S, Sen S, Ahmad T, Nadkarni GN  et al.  Automated Identification of Heart Failure with Reduced Ejection Fraction using Deep Learning-based Natural Language Processing.  medRxiv  2023 Sep 11;. pii:2023.09.10.23295315
  35. Jang SY, Park JJ, Adler E, Eshraghian E, Ahmad FS, Campagnari C, Yagil A, Greenberg B  Mortality Prediction in Patients With or Without Heart Failure Using a Machine Learning Model.  JACC Adv  2023 Sep;2(7):100554. pii:100554
  36. Chuzi S, Tanaka Y, Bavishi A, Bruce M, Van Wagner LB, Wilcox JE, Ahmad FS, Ladner DP, Lagu T, Khan SS  Association Between End-Stage Liver Disease and Incident Heart Failure in an Integrated Health System.  J Gen Intern Med  2023 Aug;38(11):2445-2452. doi:10.1007/s11606-023-08199-z
  37. Canning C, Guo J, Narang A, Thomas JD, Ahmad FS  The Emerging Role of Artificial Intelligence in Valvular Heart Disease.  Heart Fail Clin  2023 Jul;19(3):391-405. doi:10.1016/j.hfc.2023.03.001
  38. Schepart A, Burton A, Durkin L, Fuller A, Charap E, Bhambri R, Ahmad FS  Artificial intelligence-enabled tools in cardiovascular medicine: A survey of current use, perceptions, and challenges.  Cardiovasc Digit Health J  2023 Jun;4(3):101-110. doi:10.1016/j.cvdhj.2023.04.003
  39. DeRemer DL, Nguyen NK, Guha A, Ahmad FS, Cooper-DeHoff RM, Pepine CJ, Fradley MG, Gong Y  Racial and Ethnic Differences in Cardiac Surveillance Evaluation of Patients Treated With Anthracycline-Based Chemotherapy.  J Am Heart Assoc  2023 May 16;12(10):e027981. pii:e027981
  40. Chamberlain AM, Cooper-DeHoff RM, Fontil V, Nilles EK, Shaw KM, Smith M, Lin F, Vittinghoff E, Maeztu C, Todd JV  et al.  Disruption in Blood Pressure Control With the COVID-19 Pandemic: The PCORnet Blood Pressure Control Laboratory.  Mayo Clin Proc  2023 May;98(5):662-675. doi:10.1016/j.mayocp.2022.12.024
  41. Nilles EK, Champon X, Mulder H, Shaw KM, Smith M, Lampron ZM, Wozniak G, Chamberlain AM, Carton T, Viera AJ  et al.  Seasonal variation in blood pressure control across US health systems.  J Hypertens  2023 May 01;41(5):751-758. doi:10.1097/HJH.0000000000003396
  42. Hosseini M, Gao CA, Liebovitz D, Carvalho A, Ahmad FS, Luo Y, MacDonald N, Holmes K, Kho A  An exploratory survey about using ChatGPT in education, healthcare, and research.  medRxiv  2023 Apr 03;. pii:2023.03.31.23287979
  43. Gay HC, Yu J, Persell SD, Linder JA, Srivastava A, Isakova T, Huffman MD, Khan SS, Mutharasan RK, Petito LC  et al.  Comparison of Sodium-Glucose Cotransporter-2 Inhibitor and Glucagon-Like Peptide-1 Receptor Agonist Prescribing in Patients With Diabetes Mellitus With and Without Cardiovascular Disease.  Am J Cardiol  2023 Feb 15;189:121-130. doi:10.1016/j.amjcard.2022.10.041
  44. Ahmad FS, Ahmad T, Allen LA  When the Whole Is the Sum of Its Parts: Validation of the Heart Failure Collaboratory Medication Composite Score in Denmark.  Circ Heart Fail  2023 Feb;16(2):e010309. doi:10.1161/CIRCHEARTFAILURE.122.010309
  45. Li Y, Wehbe RM, Ahmad FS, Wang H, Luo Y  A comparative study of pretrained language models for long clinical text.  J Am Med Inform Assoc  2023 Jan 18;30(2):340-347. doi:10.1093/jamia/ocac225
  46. Adekkanattu P, Rasmussen LV, Pacheco JA, Kabariti J, Stone DJ, Yu Y, Jiang G, Luo Y, Brandt PS, Xu Z  et al.  Prediction of left ventricular ejection fraction changes in heart failure patients using machine learning and electronic health records: a multi-site study.  Sci Rep  2023 Jan 06;13(1):294. pii:294
  47. Ahmad FS, Persell SD  Nudging to Improve Cardiovascular Care-Clinicians, Patients, or Both.  JAMA Cardiol  2023 Jan 01;8(1):31-32. doi:10.1001/jamacardio.2022.4382
  48. Tibrewala A, Wehbe RM, Wu T, Harap R, Ghafourian K, Wilcox JE, Okwuosa IS, Vorovich EE, Ahmad FS, Yancy C  et al.  Hyponatremia Is a Powerful Predictor of Poor Prognosis in Left Ventricular Assist Device Patients.  ASAIO J  2022 Dec 01;68(12):1475-1482. doi:10.1097/MAT.0000000000001691
  49. Cheema B, Mutharasan RK, Sharma A, Jacobs M, Powers K, Lehrer S, Wehbe FH, Ronald J, Pifer L, Rich JD  et al.  Augmented Intelligence to Identify Patients With Advanced Heart Failure in an Integrated Health System.  JACC Adv  2022 Oct;1(4). pii:100123
  50. Ahmad FS, Jackson KL, Yount SE, Rothrock NE, Kallen MA, Lacson L, Bilimoria KY, Kho AN, Mutharasan RK, McCullough PA  et al.  The development and initial validation of the PROMIS®+HF-27 and PROMIS+HF-10 profiles.  ESC Heart Fail  2022 Oct;9(5):3380-3392. doi:10.1002/ehf2.14061