About Our Lab
The Oliver Lab focuses on understanding how each specific cell type and organ acquires all its specific and unique morphological and functional characteristics during embryogenesis. Alterations in the cellular and molecular mechanisms controlling organ formation can result in major defects and pathological alterations. Our rationale is that a better knowledge of the basic processes controlling normal organogenesis will facilitate our understanding of disease. Our goal is to dissect the specific stepwise molecular processes that make each organ unique and perfect. Our major research interests are the forebrain, visual system and the lymphatic vasculature and to address those questions we use a combination of animal models and 3D organ culture systems, stem cells and iPS cells.
- See our recent publication, "Lymphangiogenesis: Origin, Specification, and Cell Fate Determination."
- Dr. XiaoLei Liu receives Lymphatic Education & Research Network (LE&RN) Young Investigator Conference Scholarship Award.
- Postdoctoral positions available in the Oliver lab!
- June 8- June 11, 2017: Join us at the Lymphatic Conference hosted by Northwestern University in Chicago. More information can be found here.
Srinivasan, S., Escobedo, N., Yang, Y., Interiano, A., Dillard, M.E., Finkelstein, D., Mukatira, S., Gil, HJ., Nurmi, H., Alitalo, K., and Oliver, G. (2014). Prox1-Vegfr3 feedback loop maintains the identity and the number of lymphatic endothelial cell progenitors (Genes & Dev, 28, 2175-2187).
Lavado, A., and Oliver, G. (2014). Jagged1 is necessary for postnatal and adult neurogenesis in the dentate gyrus. Developmental Biology 388, 11-21.
Srinivasan, S. and Oliver, G. (2011). Prox1 dosage controls the number of lymphatic endothelial cell progenitors and the formation of the lympho-venous valves. Genes & Dev 25, 2187-97.View more publications