Northwestern University Feinberg School of Medicine

Guillermo Oliver Lab

About Our Lab

The Oliver Lab focuses on understanding how each specific cell type and organ acquires all its specific and unique morphological and functional characteristics during embryogenesis. Alterations in the cellular and molecular mechanisms controlling organ formation can result in major defects and pathological alterations. Our rationale is that a better knowledge of the basic processes controlling normal organogenesis will facilitate our understanding of disease. Our goal is to dissect the specific stepwise molecular processes that make each organ unique and perfect. Our major research interests are the forebrain, visual system and the lymphatic vasculature and to address those questions we use a combination of animal models and 3D organ culture systems, including ES and iPS cells. 


Selected Publications

Srinivasan, S., Escobedo, N., Yang, Y., Interiano, A., Dillard, M.E., Finkelstein, D., Mukatira, S., Gil, HJ., Nurmi, H., Alitalo, K., and Oliver, G. (2014). Prox1-Vegfr3 feedback loop maintains the identity and the number of lymphatic endothelial cell progenitors (Genes & Dev, 28, 2175-2187).

Lavado, A., and Oliver, G. (2014). Jagged1 is necessary for postnatal and adult neurogenesis in the dentate gyrus. Developmental Biology 388, 11-21.

Srinivasan, S. and Oliver, G. (2011). Prox1 dosage controls the number of lymphatic endothelial cell progenitors and the formation of the lympho-venous valves. Genes & Dev 25, 2187-97.

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Guillermo Oliver, PhD

Guillermo Oliver, PhD
Director, Center for Vascular and Developmental Biology

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