Northwestern University Feinberg School of Medicine

Shahabi Laboratory

Recent Publications

Learn more about the work that we do in the Shahabi Laboratory through our recent publications.

  1. Goodman CR, Seagle BL, Kocherginsky M, Donnelly ED, Shahabi S, Strauss JB  21-gene recurrence score assay predicts benefit of post-mastectomy radiotherapy in T1-2 N1 breast cancer.  Clin Cancer Res  2018 Apr 23;. pii:clincanres.3169.2017
  2. Luo CH, Zhao M, Tang YX, Shahabi S, Fang KN, Chen Y, Tang Y, Chen XY, Wang J, Zhou HH  Increased HE4 mRNA Expression Correlates with High Level Of eIF3a mRNA And Better Survival in Women with Epithelial Ovarian Cancer.  J Cancer  2018;9(6):1088-1095. doi:10.7150/jca.23639
  3. Almassalha LM, Bauer GM, Wu W, Cherkezyan L, Zhang D, Kendra A, Gladstein S, Chandler JE, VanDerway D, Seagle BL, Ugolkov A, Billadeau DD, O'Halloran TV, Mazar AP, Roy HK, Szleifer I, Shahabi S, Backman V  Macrogenomic engineering via modulation of the scaling of chromatin packing density.  Nat Biomed Eng  2017 Nov;1(11):902-913. doi:10.1038/s41551-017-0153-2
  4. Zhang Q, Kanis MJ, Ubago J, Liu D, Scholtens DM, Strohl AE, Lurain JR, Shahabi S, Kong B, Wei JJ  The selected biomarker analysis in five types of uterine smooth muscle tumors.  Hum Pathol  2017 Dec 16;. pii:S0046-8177(17)30471-9
  5. Seagle BL, Alexander AL, Lantsman T, Shahabi S  Prognosis and treatment of positive peritoneal cytology in early endometrial cancer: matched cohort analyses from the National Cancer Database.  Am J Obstet Gynecol  2018 Mar;218(3):329.e1-329.e15. pii:S0002-9378(17)32472-9
  6. Seagle BL, Alexander AL, Strohl AE, Shahabi S  Discussing sarcoma risks during informed consent for nonhysterectomy management of fibroids: an unmet need.  Am J Obstet Gynecol  2018 Jan;218(1):103.e1-103.e5. pii:S0002-9378(17)31129-8
  7. Seagle BL, Miller ES, Strohl AE, Hoekstra A, Shahabi S  Transversus abdominis plane block with liposomal bupivacaine compared to oral opioids alone for acute postoperative pain after laparoscopic hysterectomy for early endometrial cancer: a cost-effectiveness analysis.  Gynecol Oncol Res Pract  2017;4:12. doi:10.1186/s40661-017-0048-7
  8. Seagle BL, Graves S, Strohl AE, Shahabi S  Survival After Primary Debulking Surgery Compared With Neoadjuvant Chemotherapy in Advanced Ovarian Cancer: A National Cancer Database Study.  Int J Gynecol Cancer  2017 10;27(8):1610-1618. doi:10.1097/IGC.0000000000001072
  9. Seagle BL, Shilpi A, Buchanan S, Goodman C, Shahabi S  Low-grade and high-grade endometrial stromal sarcoma: A National Cancer Database study.  Gynecol Oncol  2017 08;146(2):254-262. pii:S0090-8258(17)30892-2
  10. Malagon-Blackwell EM, Seagle BL, Nieves-Neira W, Shahabi S  The Hispanic Paradox in endometrial cancer: A National Cancer Database study.  Gynecol Oncol  2017 08;146(2):351-358. pii:S0090-8258(17)30882-X
  11. Seagle BL, Ann P, Butler S, Shahabi S  Ovarian granulosa cell tumor: A National Cancer Database study.  Gynecol Oncol  2017 08;146(2):285-291. pii:S0090-8258(17)30873-9
  12. Seagle BL, Kanis M, Kocherginsky M, Strauss JB, Shahabi S  Stage I uterine carcinosarcoma: Matched cohort analyses for lymphadenectomy, chemotherapy, and brachytherapy.  Gynecol Oncol  2017 Apr;145(1):71-77. pii:S0090-8258(17)30048-3
  13. Seagle BL, Sobecki-Rausch J, Strohl AE, Shilpi A, Grace A, Shahabi S  Prognosis and treatment of uterine leiomyosarcoma: A National Cancer Database study.  Gynecol Oncol  2017 Apr;145(1):61-70. pii:S0090-8258(17)30123-3
  14. Seagle BL, Shahabi S  Cost-effectiveness analysis of dose-dense versus standard intravenous chemotherapy for ovarian cancer: An economic analysis of results from the Gynecologic Oncology Group protocol 262 randomized controlled trial.  Gynecol Oncol  2017 Apr;145(1):9-14. pii:S0090-8258(17)30125-7
  15. Graves S, Seagle BL, Strohl AE, Shahabi S, Nieves-Neira W  Survival After Pelvic Exenteration for Cervical Cancer: A National Cancer Database Study.  Int J Gynecol Cancer  2017 02;27(2):390-395. doi:10.1097/IGC.0000000000000884
  16. Seagle BL, Butler SK, Strohl AE, Nieves-Neira W, Shahabi S  Chemotherapy delay after primary debulking surgery for ovarian cancer.  Gynecol Oncol  2017 Feb;144(2):260-265. pii:S0090-8258(16)31578-5
  17. Seagle BL, Kanis M, Strohl AE, Shahabi S  Survival of women with Mullerian adenosarcoma: A National Cancer Data Base study.  Gynecol Oncol  2016 Dec;143(3):636-641. pii:S0090-8258(16)31485-8
  18. Seagle BL, Dayno M, Strohl AE, Graves S, Nieves-Neira W, Shahabi S  Survival after pelvic exenteration for uterine malignancy: A National Cancer Data Base study.  Gynecol Oncol  2016 Dec;143(3):472-478. pii:S0090-8258(16)31495-0
  19. Tanamai VW, Seagle BL, Yeh JY, Brady B, Miller CB, Sena S, Dodge J, Shahabi S, Samuelson R, Norwitz ER, Luo G  Urine Protein/Creatinine Ratios during Labor: A Prospective Observational Study.  PLoS One  2016;11(8):e0160453. doi:10.1371/journal.pone.0160453
  20. Seagle BL, Dandapani M, Yeh JY, Shahabi S  Wnt Signaling and Survival of Women With High-Grade Serous Ovarian Cancer: A Brief Report.  Int J Gynecol Cancer  2016 07;26(6):1078-80. doi:10.1097/IGC.0000000000000726
  21. Strohl AE, Feinglass JM, Shahabi S, Simon MA  Surgical wait time: A new health indicator in women with endometrial cancer.  Gynecol Oncol  2016 06;141(3):511-515. pii:S0090-8258(16)30146-9
  22. Seagle BL, Eng KH, Yeh JY, Dandapani M, Schiller E, Samuelson R, Odunsi K, Shahabi S  Discovery of candidate tumor biomarkers for treatment with intraperitoneal chemotherapy for ovarian cancer.  Sci Rep  2016 Feb 17;6:21591. doi:10.1038/srep21591
  23. Dandapani M, Seagle BL, Chacho MS, Shahabi S  Delayed and clinically isolated port site carcinosarcoma recurrence as an early indicator of disseminated disease.  Gynecol Oncol Rep  2015 Nov;14:12-5. doi:10.1016/j.gore.2015.08.003
  24. Shahabi S, Fazlalizadeh H, Stedman J, Chuang L, Shariftabrizi A, Ram R  The impact of international economic sanctions on Iranian cancer healthcare.  Health Policy  2015 Oct;119(10):1309-18. doi:10.1016/j.healthpol.2015.08.012
  25. Seagle BL, Eng KH, Dandapani M, Yeh JY, Odunsi K, Shahabi S  Survival of patients with structurally-grouped TP53 mutations in ovarian and breast cancers.  Oncotarget  2015 Jul 30;6(21):18641-52
  26. Dandapani M, Seagle BL, Abdullah A, Hatfield B, Samuelson R, Shahabi S  Metastatic Uterine Leiomyosarcoma Involving Bilateral Ovarian Stroma without Capsular Involvement Implies a Local Route of Hematogenous Dissemination.  Case Rep Obstet Gynecol  2015;2015:950373. doi:10.1155/2015/950373
  27. Seagle BL, Yang CP, Eng KH, Dandapani M, Odunsi-Akanji O, Goldberg GL, Odunsi K, Horwitz SB, Shahabi S  TP53 hot spot mutations in ovarian cancer: selective resistance to microtubule stabilizers in vitro and differential survival outcomes from The Cancer Genome Atlas.  Gynecol Oncol  2015 Jul;138(1):159-64. doi:10.1016/j.ygyno.2015.04.039