Northwestern University Feinberg School of Medicine

Mandel Laboratory



Henry CS, Rotman E, Lathem WW, Tyo KEJ, Hauser AR, Mandel MJ. 2017. Generation and validation of the iKp1289 metabolic model for Klebsiella pneumoniae KPPR1. J Infect Dis 215 (suppl_1): S37-S43.


Mandel MJ, Dunn AK. 2016. Impact and influence of the natural Vibrio-squid symbiosis in understanding bacterial-animal interactions. Frontiers in Microbiology. doi: 10.3389/fmicb.2016.01982

Brooks JF, Mandel MJ. 2016. The histidine kinase BinK is a negative regulator of biofilm formation and squid colonization. J Bacteriol 198:2596-2607.


Prince BT, Mandel MJ, Nadeau K, Singh AM. 2015. Gut microbiome and the development of food allergy and allergic disease. Pediatr Clin North Am 62:1479-92.

Dunn AK, Rader BA, Stabb EV, Mandel MJ. 2015. Regulation of bioluminescence in Photobacterium leiognathi strain KNH6. J Bacteriol 197:3676-85.

Singh P, Brooks JF, Ray VA, Mandel MJ, Visick KL. 2015. CysK Plays a Role in Biofilm Formation and Colonization by Vibrio fischeri. Appl Environ Microbiol 81:5223-34.

Brooks JF, Gyllborg MC, Kocher AA, Markey LEH, Mandel MJ. 2015. TfoX-based genetic mapping identifies Vibrio fischeri strain-level differences and reveals a common lineage of laboratory strains. J Bacteriol 197:1065-1074.


Brooks JF, Gyllborg MC, Cronin DC, Quillin SJ, Mallama CA, Foxall R, Whistler CA, Goodman AL, Mandel MJ. 2014. Global discovery of colonization determinants in the squid symbiont Vibrio fischeri. Proc Natl Acad Sci USA 111:17284–17289.

Wang N, Ozer EA, Mandel MJ, Hauser AR. 2014. Genome-wide identification of Acinetobacter baumannii genes necessary for persistence in the lung. mBio 5:e01163-14.

Zafar MA, Carabetta VJ, Mandel MJ, Silhavy TJ. 2014. Transcriptional occlusion caused by overlapping promoters. Proc Natl Acad Sci USA 111:1557-61.


Brennan CA, Mandel MJ, Gyllborg MC, Thomasgard KA, Ruby EG. 2013. Genetic determinants of swimming motility in the squid light-organ symbiont Vibrio fischeri. MicrobiologyOpen 2:576-94.

Brennan CA, DeLoney-Marino CL Mandel MJ. 2013. The chemoreceptor VfcA mediates amino acid chemotaxis in Vibrio fischeri. Appl Environ Microbiol 79:1889-1896.


Mandel MJ, Schaefer AL, Brennan CA, Heath-Heckman EAC, DeLoney-Marino CL, McFall-Ngai MJ, Ruby EG. 2012. Squid-derived chitin oligosaccharides are a chemotactic signal during colonization by Vibrio fischeri. Appl Environ Microbiol 78:4620-4626.

Naughton LM, Mandel MJ. 2012. Colonization of Euprymna scolopes squid by Vibrio fischeri. J Vis Exp 61:e3758, doi: 10.3791/3758.

Gyllborg MC, Sahl JW, Cronin III DC, Rasko DA, Mandel MJ. 2012. Draft genome sequence of Vibrio fischeri SR5, a strain isolated from the light organ of the Mediterranean squid Sepiola robusta. J Bacteriol 194:1639.

Pearce MM, Theodoropoulos N, Mandel MJ, Brown E, Reed KD, Cianciotto NP. 2012. Legionella cardiaca sp. nov., isolated from a case of native valve endocarditis in a human heart. Int J Syst Evol Microbiol 62:2946-2954.

Post DM, Yu L, Krasity BC, Choudhury B, Mandel MJ, Brennan CA, Ruby EG, McFall-Ngai MJ, Gibson BW, Apicella MA. 2012. The O-antigen and core carbohydrate of Vibrio fischeri lipopolysaccharide: Composition and analysis of their role in Euprymna scolopes light organ colonization. J Biol Chem 287:8515-30.


Bose JL, Wollenberg MS, Colton D, Mandel MJ, Septer AN, Dunn AK, Stabb EV. 2011. Contribution of rapid evolution of the luxR-luxI intergenic region to the diverse bioluminescence outputs of Vibrio fischeri strains isolated from different environments. Appl Environ Microbiol 77:2445-2457.


Mandel MJ. 2010. Models and approaches to dissect host-symbiont specificity. Trends Microbiol 18:504-511.

Wier AM, Nyholm SV, Mandel MJ, Massengo-Tiassé RP, Schaefer AL, Koroleva I, Splinter BonDurant S, Brown B, Manzella L, Snir E, Almabrazi H, Scheetz TE, Bonaldo Mde F, Casavant TL, Soares MB, Cronan JE, Reed JL, Ruby EG, McFall-Ngai MJ. 2010. Transcriptional patterns in both host and bacterium underlie a daily rhythm of ultrastructural and metabolic change in a beneficial symbiosis. Proc Natl Acad Sci USA 107:2259-2264.


Mandel MJ, Wollenberg MS, Stabb EV, Visick KL, Ruby EG. 2009. A single regulatory gene is sufficient to alter bacterial host range. Nature 458:215-218.


Studer SV, Mandel MJ, Ruby EG. 2008. AinS quorum sensing regulates the Vibrio fischeri acetate switch. J Bacteriol 190:5915-5923.

Mandel MJ, Stabb EV, Ruby EG. 2008. Comparative genomics-based investigation of resequencing targets in Vibrio fischeri: focus on point miscalls and artefactual expansions. BMC Genomics 9:138.


Gaal T, Mandel MJ, Silhavy TJ, Gourse RL. 2006. Crl facilitates RNA polymerase holoenzyme formation. J Bacteriol 188:7966-7970.


Peterson CN, Mandel MJ, Silhavy TJ. 2005. Escherichia coli starvation diets: essential nutrients weigh in distinctly. J Bacteriol 187:7549-7553.

Mandel MJ, Silhavy TJ. 2005. Starvation for different nutrients in Escherichia coli results in differential modulation of RpoS levels and stability. J Bacteriol 187:434-442.


Mandel MJ, Ross CL, Harrison RG. 2001. Do Wolbachia infections play a role in unidirectional incompatibilities in a field cricket hybrid zone? Mol Ecol 10:703-709.

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