The primary goal of our research is to use gene discovery and molecular biology approaches to identify new treatments for epilepsy. We aim to 1) identify the genetic causes of epilepsy, 2) use stem cell models to understand how genetic mutations can cause epilepsy, 3) develop and test new therapeutics for this condition. Our work is based on the promise of precision medicine where knowledge of an individual’s genetic makeup shapes a personalized approach to care and management of epilepsy.
Esterhuizen AI, Mefford HC, Ramesar RS, Wang S, Carvill GL, Wilmshurst JM Dravet syndrome in South African infants: Tools for an early diagnosis. Seizure 2018 Nov;62:99-105.
Calhoun JD, Carvill GL Unravelling the genetic architecture of autosomal recessive epilepsy in the genomic era. J Neurogenet 2018 Sep 24;:1-18.
- Follow us on twitter @CarvillLab
- Jeff and Gemma have published a new comprehensive review on recessive causes of genetic epilepsies published in Journal of Neurogenetics
- We're recruiting a research technologist to join our team, shoot us an email if you're keen to hear more!