Northwestern University Feinberg School of Medicine

Opal Laboratory



View the Opal Laboratory's publications in PubMed


Early activation of microglia and astrocytes in mouse models of spinocerebellar ataxia type 1. Neuroscience. Epub January 2015Cvetanovic M., Ingram M., Orr, H., and Opal P. PMID: 25595967

An investigation of diffusion imaging techniques in the evaluation of spinocerebellar ataxia and multisystem atrophyJ Clin Neurosci. 2015 Jan;22(1):166-72. doi: 10.1016/j.jocn.2014.08.006. Epub 2014 Nov 26. Rozenfeld MN, Nemeth AJ, Walker MT, Mohan P, Wang X, Parrish TB, Opal P. PMID: 25439745

The histone deacetylase HDAC3 is essential for Purkinje cell function, potentially complicating the use of HDAC inhibitors in SCA1. Hum Mol Genet. 2014 Jul 15;23(14):3733-45. Venkatraman A, Hu YS, Didonna A, Cvetanovic M, Krbanjevic A, Bilesimo P, Opal P. PMID: 24594842


Explaining intermediate filament accumulation in giant axonal neuropathyRare Dis. 2013 Jun 17;1:e25378. Opal P, Goldman RD. PMID: 25003002

Giant axonal neuropathy-associated gigaxonin mutations impair intermediate filament protein degradation. J Clin Invest. 2013 May 1;123(5):1964-75. Mahammad S, Murthy SN, Didonna A, Grin B, Israeli E, Perrot R, Bomont P, Julien JP, Kuczmarski E, Opal P, Goldman RD. PMID: 23585478


LANP mediates neuritic pathology in Spinocerebellar ataxia type 1. Neurobiol Dis. 2012 Dec;48(3):526-32. Cvetanovic M, Kular RK, Opal P. PMID: 22884877


Vascular endothelial growth factor ameliorates the ataxic phenotype in a mouse model of spinocerebellar ataxia type 1. Nat Med. 2011 Oct 16;17(11):1445-7. Cvetanovic M, Patel JM, Marti HH, Kini AR, Opal P. PMID: 22001907


Cpd-1 null mice display a subtle neurological phenotype. PLoS One. 2010 Sep 9;5(9). pii: e12649. Kular RK, Gogliotti RG, Opal P. PMID: 20844742


Neuronal differentiation is regulated by leucine-rich acidic nuclear protein (LANP), a member of the inhibitor of histone acetyltransferase complex. J Biol Chem. 2009 Mar 20;284(12):7783-92. Kular RK, Cvetanovic M, Siferd S, Kini AR, Opal P. PMID: 19136565


Association of spinocerebellar ataxia type 3 and spinocerebellar ataxia type 8 microsatellite expansions: genetic counseling implications. Mov Disord. 2008 Jan;23(1):154-5. Paganoni S, Seelaus CA, Ormond KE, Opal P. PMID: 17987652


The role of LANP and ataxin 1 in E4F-mediated transcriptional repression. EMBO Rep. 2007 Jul;8(7):671-7. Cvetanovic M, Rooney RJ, Garcia JJ, Toporovskaya N, Zoghbi HY, Opal P. PMC: 1905893

Huntington's disease presenting as postsurgical psychosis. Mov Disord. 2007 Jun 15;22(8):1209-10. Paganoni S, Naidech AM, Opal P. PMID: 17443707