Publications
Learn more about the work that we do in the McNally Laboratory through our selected publications below. For a comprehensive list, please visit PubMed.
- Linder JE, Allworth A, Bland HT, Caraballo PJ, Chisholm RL, Clayton EW, Crosslin DR, Dikilitas O, DiVietro A, Esplin ED, Forman S, Freimuth RR, Gordon AS, Green R, Harden MV, Holm IA, Jarvik GP, Karlson EW, Labrecque S, Lennon NJ, Limdi NA, Mittendorf KF, Murphy SN, Orlando L, Prows CA, Rasmussen LV, Rasmussen-Torvik L, Rowley R, Sawicki KT, Schmidlen T, Terek S, Veenstra D, Velez Edwards DR, Absher D, Abul-Husn NS, Alsip J, Bangash H, Beasley M, Below JE, Berner ES, Booth J, Chung WK, Cimino JJ, Connolly J, Davis P, Devine B, Fullerton SM, Guiducci C, Habrat ML, Hain H, Hakonarson H, Harr M, Haverfield E, Hernandez V, Hoell C, Horike-Pyne M, Hripcsak G, Irvin MR, Kachulis C, Karavite D, Kenny EE, Khan A, Kiryluk K, Korf B, Kottyan L, Kullo IJ, Larkin K, Liu C, Malolepsza E, Manolio TA, May T, McNally EM, Mentch F, Miller A, Mooney SD, Murali P, Mutai B, Muthu N, Namjou B, Perez EF, Puckelwartz MJ, Rakhra-Burris T, Roden DM, Rosenthal EA, Saadatagah S, Sabatello M, Schaid DJ, Schultz B, Seabolt L, Shaibi GQ, Sharp RR, Shirts B, Smith ME, Smoller JW, Sterling R, Suckiel SA, Thayer J, Tiwari HK, Trinidad SB, Walunas T, Wei WQ, Wells QS, Weng C, Wiesner GL, Wiley K, eMERGE Consortium, Peterson JF Returning integrated genomic risk and clinical recommendations: The eMERGE study. Genet Med 2023 Apr;25(4):100006 PMID: 36621880, PMCID: PMC10085845
- Levin MG, Tsao NL, Singhal P, Liu C, Vy HMT, Paranjpe I, Backman JD, Bellomo TR, Bone WP, Biddinger KJ, Hui Q, Dikilitas O, Satterfield BA, Yang Y, Morley MP, Bradford Y, Burke M, Reza N, Charest B, Regeneron Genetics Center, Judy RL, Puckelwartz MJ, Hakonarson H, Khan A, Kottyan LC, Kullo I, Luo Y, McNally EM, Rasmussen-Torvik LJ, Day SM, Do R, Phillips LS, Ellinor PT, Nadkarni GN, Ritchie MD, Arany Z, Cappola TP, Margulies KB, Aragam KG, Haggerty CM, Joseph J, Sun YV, Voight BF, Damrauer SM Genome-wide association and multi-trait analyses characterize the common genetic architecture of heart failure. Nat Commun 2022 Nov 14;13(1):6914 PMID: 36376295, PMCID: PMC9663424
- Dellefave-Castillo LM, Cirino AL, Callis TE, Esplin ED, Garcia J, Hatchell KE, Johnson B, Morales A, Regalado E, Rojahn S, Vatta M, Nussbaum RL, McNally EM Assessment of the Diagnostic Yield of Combined Cardiomyopathy and Arrhythmia Genetic Testing. JAMA Cardiol 2022 Sep 1;7(9):966-974 PMID: 35947370, PMCID: PMC9366660
- Fischer JA, Monroe TO, Pesce LL, Sawicki KT, Quattrocelli M, Bauer R, Kearns SD, Wolf MJ, Puckelwartz MJ, McNally EM Opposing effects of genetic variation in MTCH2 for obesity versus heart failure. Hum Mol Genet 2023 Jan 1;32(1):15-29 PMID: 35904451, PMCID: PMC9837833
- Demonbreun AR, Bogdanovic E, Vaught LA, Reiser NL, Fallon KS, Long AM, Oosterbaan CC, Hadhazy M, Page PG, Joseph PRB, Cowen G, Telenson AM, Khatri A, Sadleir KR, Vassar R, McNally EM A conserved annexin A6-mediated membrane repair mechanism in muscle, heart, and nerve. JCI Insight 2022 Jul 22;7(14) PMID: 35866481, PMCID: PMC9431694
- Barefield DY, Yamakawa S, Tahtah I, Sell JJ, Broman M, Laforest B, Harris S, Alvarez-Arce A, Araujo KN, Puckelwartz MJ, Wasserstrom JA, Fishman GI, McNally EM Partial and complete loss of myosin binding protein H-like cause cardiac conduction defects. J Mol Cell Cardiol 2022 Aug;169:28-40 PMID: 35533732, PMCID: PMC9329245
- Quattrocelli M, Wintzinger M, Miz K, Panta M, Prabakaran AD, Barish GD, Chandel NS, McNally EM Intermittent prednisone treatment in mice promotes exercise tolerance in obesity through adiponectin. J Exp Med 2022 May 2;219(5) PMID: 35363257, PMCID: PMC8980841
- Salamone IM, Quattrocelli M, Barefield DY, Page PG, Tahtah I, Hadhazy M, Tomar G, McNally EM Intermittent glucocorticoid treatment enhances skeletal muscle performance through sexually dimorphic mechanisms. J Clin Invest 2022 Mar 15;132(6) PMID: 35143417, PMCID: PMC8920338
- Glazer AM, Davogustto G, Shaffer CM, Vanoye CG, Desai RR, Farber-Eger EH, Dikilitas O, Shang N, Pacheco JA, Yang T, Muhammad A, Mosley JD, Van Driest SL, Wells QS, Shaffer LL, Kalash OR, Wada Y, Bland HT, Yoneda ZT, Mitchell DW, Kroncke BM, Kullo IJ, Jarvik GP, Gordon AS, Larson EB, Manolio TA, Mirshahi T, Luo JZ, Schaid D, Namjou B, Alsaied T, Singh R, Singhal A, Liu C, Weng C, Hripcsak G, Ralston JD, McNally EM, Chung WK, Carrell DS, Leppig KA, Hakonarson H, Sleiman P, Sohn S, Glessner J, eMERGE Network, Denny J, Wei WQ, George AL Jr, Shoemaker MB, Roden DM Arrhythmia Variant Associations and Reclassifications in the eMERGE-III Sequencing Study. Circulation 2022 Mar 22;145(12):877-891 PMID: 34930020, PMCID: PMC8940719
- Demonbreun AR, Fallon KS, Oosterbaan CC, Vaught LA, Reiser NL, Bogdanovic E, Velez MP, Salamone IM, Page PGT, Hadhazy M, Quattrocelli M, Barefield DY, Wood LD, Gonzalez JP, Morris C, McNally EM Anti-latent TGFβ binding protein 4 antibody improves muscle function and reduces muscle fibrosis in muscular dystrophy. Sci Transl Med 2021 Sep 8;13(610):eabf0376 PMID: 34516828, PMCID: PMC9559620
- Webster G, Puckelwartz MJ, Pesce LL, Dellefave-Castillo LM, Vanoye CG, Potet F, Page P, Kearns SD, Pottinger T, White S, Arunkumar P, Olson R, Kofman A, Ibrahim N, Ing A, Brew C, Yap KL, Kadri S, George AL Jr, McNally EM Genomic Autopsy of Sudden Deaths in Young Individuals. JAMA Cardiol 2021 Nov 1;6(11):1247-1256 PMID: 34379075, PMCID: PMC8358810
- Puckelwartz MJ, Pesce LL, Dellefave-Castillo LM, Wheeler MT, Pottinger TD, Robinson AC, Kearns SD, Gacita AM, Schoppen ZJ, Pan W, Kim G, Wilcox JE, Anderson AS, Ashley EA, Day SM, Cappola T, Dorn GW 2nd, McNally EM Genomic Context Differs Between Human Dilated Cardiomyopathy and Hypertrophic Cardiomyopathy. J Am Heart Assoc 2021 Apr 6;10(7):e019944 PMID: 33764162, PMCID: PMC8174318
- Gacita AM, Fullenkamp DE, Ohiri J, Pottinger T, Puckelwartz MJ, Nobrega MA, McNally EM Genetic Variation in Enhancers Modifies Cardiomyopathy Gene Expression and Progression. Circulation 2021 Mar 30;143(13):1302-1316 PMID: 33478249, PMCID: PMC8009836
- Liu J, Campagna J, John V, Damoiseaux R, Mokhonova E, Becerra D, Meng H, McNally EM, Pyle AD, Kramerova I, Spencer MJ A Small-Molecule Approach to Restore a Slow-Oxidative Phenotype and Defective CaMKIIβ Signaling in Limb Girdle Muscular Dystrophy. Cell Rep Med 2020 Oct 20;1(7):100122 PMID: 33205074, PMCID: PMC7659555
- Gacita AM, Dellefave-Castillo L, Page PGT, Barefield DY, Wasserstrom JA, Puckelwartz MJ, Nobrega MA, McNally EM Altered Enhancer and Promoter Usage Leads to Differential Gene Expression in the Normal and Failed Human Heart. Circ Heart Fail 2020 Oct;13(10):e006926 PMID: 32993371, PMCID: PMC7577963