About Our Lab
Research in the lab examines the neural and computational principles of reward-guided behavior, with a focus on odor-guided behavior. We study brain systems involved in reward processing, learning, generalization, and decision-making such as the striatum and the orbitofrontal cortex. For this, we use a combination of human olfactory psychophysics, computational modeling, fMRI and advanced multivariate analyses techniques borrowed from machine learning. This research may pave the way for understanding decision-making deficits in neurological diseases and addiction, and should ultimately lead to novel diagnostic markers and treatment strategies for these disorders.
Howard JD, Kahnt T. Identity-specific reward representations in orbitofrontal cortex are modulated by selective devaluation. Journal of Neuroscience 2017 Mar 8; 37(10):2627-2638. PMID: 28159906.
Kahnt T, Tobler PN. Dopamine modulates the functional organization of the orbitofrontal cortex. Journal of Neuroscience 2017 Feb 8; 37(6):1493-1504. PMID: 28069917.
Howard JD, Gottfried JA, Tobler PN, Kahnt T. Identity-specific coding of future rewards in the human orbitofrontal cortex. Proc Natl Acad Sci USA 2015, 112(16):5195-200. PMID: 25848032
News & Events
Our work in the news:
Giving Proof (New York Times Magazine, September 14, 2017)
After a Meal, Foods Aren't the Same in the Orbitofrontal Cortex (Neuronline.org, June 8, 2017)
Food Odors Are More Enticing to Sleep-Deprived Brains (ScienceNews.org, April 2, 2017)